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Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert™ MTB/RIF era
Sabine M Hermans, Juliet A Babirye, Olive Mbabazi, Francis Kakooza, Robert Colebunders, Barbara Castelnuovo, Christine Sekaggya-Wiltshire, Rosalind Parkes-Ratanshi, Yukari C Manabe
Apr 09, 2019
BACKGROUND: The Xpert™ MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high burden countries to increase case finding among HIV...
Empirical treatment HIV Infections/complications Molecular diagnostic techniques/methods Tuberculosis pulmonary/diagnosis Tuberculosis pulmonary/epidemiology Adult CD4 Lymphocyte Count Cohort Studies Coinfection Female HIV Infections Humans Male Microscopy Molecular Diagnostic Techniques Mycobacterium tuberculosis Prospective Studies Sensitivity and Specificity Sputum Tuberculosis Uganda