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Cover Image for Indirect serum biomarkers perform sub optimally in screening for significant liver fibrosis among HIV-infected and uninfected adults in Uganda.

Indirect serum biomarkers perform sub optimally in screening for significant liver fibrosis among HIV-infected and uninfected adults in Uganda.

Clara Wekesa, Rosalind Parkes-Ratanshi, Gregory D Kirk, Jim Aizire, Ponsiano Ocama

Apr 12, 2023

INTRODUCTION: Indirect serum bio-markers present an acceptable noninvasive and cheap alternative for screening of significant liver fibrosis (SLF). Evaluation of their use in resource limited settings is important to determine...

Fibroscan® HIV/AIDS liver fibrosis sub Saharan Africa serum bio-markers Humans Adult Cross-Sectional Studies Uganda Platelet Count Severity of Illness Index Liver Cirrhosis Biomarkers ROC Curve Aspartate Aminotransferases HIV Infections Liver

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Determinants of QuantiFERON Plus-diagnosed tuberculosis infection in adult Ugandan TB contacts

Jonathan Mayito, Adrian R Martineau, Divya Tiwari, Lydia Nakiyingi, David P Kateete, Stephen T Reece, Irene Andia Biraro

Apr 17, 2023

Background

The tuberculin skin test is commonly used to diagnose latent tuberculosis infection (LTBI) in resource-limited settings, but its specificity is limited by factors including cross-reactivity with BCG vaccine...

Humans Tuberculosis HIV Infections Tuberculin Test Cross-Sectional Studies Adult Uganda Female Male Latent Tuberculosis Interferon-gamma Release Tests

Published by: PLOS ONE