Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.
Jonathan Gilley,
Kunie Ando,
Anjan Seereeram,
Teresa Rodríguez-Martín,
Amy M Pooler,
Laura Sturdee,
Brian H Anderton,
Jean-Pierre Brion,
Diane P Hanger,
Michael P Coleman
Jun 18, 2018
Hyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are key features of Alzheimer's disease and other tauopathies. To investigate the involvement of tau phosphorylation in the pathological...