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Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration-probing the role of PPARα.
James A Horscroft, Katie A O'Brien, Anna D Clark, Ross T Lindsay, Alice Strang Steel, Nathan EK Procter, Jules Devaux, Michael Frenneaux, Stephen DR Harridge, Andrew J Murray
Feb 27, 2019
Dietary inorganic nitrate prevents aspects of cardiac mitochondrial dysfunction induced by hypoxia, although the mechanism is not completely understood. In both heart and skeletal muscle, nitrate increases fatty acid oxidation...