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Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.
Miriam R Berry, Rebeccah J Mathews, John R Ferdinand, Chenzhi Jing, Kevin W Loudon, Elizabeth Wlodek, Thomas W Dennison, Christoph Kuper, Wolfgang Neuhofer, Menna R Clatworthy
Jun 22, 2018
Lower urinary tract infections are among the most common human bacterial infections, but extension to the kidneys is rare. This has been attributed to mechanical forces, such as urine flow, that prevent the ascent of bladder...
CCL2 NAFT5 Diabetes Insipidus Kidney macrophage monocyte salt sodium Urinary tract infection uropathogenic E. coli Animals Cell Line Chemokine CCL2 Chemokines Diabetes Insipidus Humans Kidney Kidney Medulla Lipopolysaccharide Receptors Mice Mice Inbred C57BL Monocytes Phagocytes salinity sodium Transcription Factors Urinary Tract Infections Urine Uropathogenic Escherichia coli
Identification of Structural and Molecular Signatures Mediating Adaptive Changes in the Mouse Kidney in Response to Pregnancy.
Jorge Lopez-Tello, Maria Angeles Jimenez-Martinez, Esteban Salazar-Petres, Ritik Patel, Amy L George, Richard G Kay, Amanda N Sferruzzi-Perri
Jul 10, 2022
Pregnancy is characterized by adaptations in the function of several maternal body systems that ensure the development of the fetus whilst maintaining health of the mother. The renal system is responsible for water and...