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The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site.
Jonathan H Clarke, Maria-Luisa Giudici, John E Burke, Roger L Williams, David J Maloney, Juan Marugan, Robin F Irvine
Feb 18, 2015
Amino Acid Substitution Animals Binding Sites Cell Differentiation Cell Line Cell Membrane Cell Polarity Deuterium Exchange Measurement Enzyme Inhibitors Isoenzymes Kidney Cortex Mice Models Molecular Mutant Proteins Phosphatidylinositol Phosphates Phosphotransferases (Alcohol Group Acceptor) Protein Conformation Protein Transport Quinazolines RNA Interference Recombinant Proteins Thiophenes