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Fast, reliable docking of models into cryo-EM maps requires understanding of the errors in the maps and the models. Likelihood-based approaches to errors have proven to be powerful and adaptable in experimental structural...

cryo-EM docking Information Gain likelihood Cryoelectron Microscopy Likelihood Functions Models Molecular Crystallography

Optimized docking of models into cryo-EM maps requires exploiting an understanding of the signal expected in the data to minimize the calculation time while maintaining sufficient signal. The likelihood-based rotation function...

cryo-EM docking Information Gain likelihood Proteins Likelihood Functions Models Molecular Cryoelectron Microscopy Crystallography X-Ray Protein Conformation