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Adenosine Triphosphate Animals Arthritis Juvenile Bacteriolysis Cells Cultured Crohn Disease Energy Metabolism Fatty Acid Synthase Type I Genetic Predisposition to Disease Humans Infections Inflammasomes Intracellular Signaling Peptides and Proteins Leprosy Lipid Metabolism MACROPHAGES Mice Mice Inbred C57BL Mice Knockout NADPH Oxidases Oxidation-Reduction Polymorphism Single Nucleotide Proteins risk Shock Septic

Microglia neurodegeneration Neuroinflammation Phagocytosis Phagoptosis Amyloid beta-Peptides Carbazoles Carcinogens Cells Cultured Enzyme Activation Enzyme Inhibitors Humans Indoles Maleimides Microglia NADPH Oxidases Neurons Phagocytosis Protein Kinase C Tetradecanoylphorbol Acetate

Mutations in the human NBEAL2 gene cause gray platelet syndrome (GPS), a bleeding diathesis characterized by a lack of α granules in platelets. The functions of the NBEAL2 protein have not been explored outside platelet biology...

Animals Blood Platelets Blood Proteins Cytosol Gray Platelet Syndrome Humans Immune System Immunophenotyping Killer Cells Natural Mice Mice Knockout Mutation NADPH Oxidases Neutrophils Phenotype Staphylococcal Infections Staphylococcus aureus

Animals Cytochrome b Group Endoplasmic Reticulum HEK293 Cells Humans Immunity Innate MACROPHAGES Membrane Glycoproteins Membrane Proteins Mice Mice Inbred C57BL NADPH Oxidase 2 NADPH Oxidases Neutrophils Phagocytes Phagocytosis Reactive Oxygen Species Respiratory Burst

NADPH oxidase OST complex P2X receptor T cells chaperone immunology inflammasome Inflammation MOUSE Humans Animals Mice NADPH Oxidases Reactive Oxygen Species Phagocytes Granulomatous Disease Chronic Signal Transduction

Altitude Angiotensinogen Case-Control Studies Female Fetal Hypoxia Humans Hypoxia-Inducible Factor 1 NADPH Oxidases Oxidative Stress Placenta pre-eclampsia Pregnancy RNA Messenger Receptors Angiotensin Renin Renin-Angiotensin System

Understanding the molecular mechanisms that promote successful tissue regeneration is critical for continued advancements in regenerative medicine. Vertebrate amphibian tadpoles of the species Xenopus laevis and Xenopus...

Amputation Surgical Animals Animals Genetically Modified antioxidants Cell Proliferation Enzyme Inhibitors Fibroblast Growth Factors Gene Expression Regulation Hydrogen Peroxide Larva NADPH Oxidases Oligonucleotides Antisense Reactive Oxygen Species Regeneration Tail Time Factors Wnt Proteins Wnt Signaling Pathway Xenopus Proteins Xenopus laevis beta Catenin

Drosophila NADPH Oxidases Aquaporins Dendrites plasticity Reactive Oxygen Species

Chlamydomonas NADPH oxidase alga biophotovoltaic Energy biofuels Chlamydomonas reinhardtii Electricity Extracellular Space Genetic Complementation Test LIGHT NADPH Oxidases Plant Proteins Superoxides

Staphylococcus aureus is a major human pathogen causing multiple pathologies, from cutaneous lesions to life-threatening sepsis. Although neutrophils contribute to immunity against S. aureus, multiple lines of evidence suggest...

Autophagy NADPH oxidase ROS Staphylococcus aureus lc3-associated phagocytosis (LAP) neutrophil Zebrafish Animals Animals Genetically Modified Autophagy Intracellular Space Kinetics MACROPHAGES Microtubule-Associated Proteins NADPH Oxidases Neutrophils Phagocytosis Phagosomes Protein Aggregates Sequestosome-1 Protein Staphylococcus aureus Zebrafish Zebrafish Proteins

Animals Bone Marrow Transplantation Cells Cultured Gene Knockdown Techniques Granulomatous Disease Chronic Humans Lymphohistiocytosis Hemophagocytic Male Membrane Proteins Mice NADPH Oxidases Oxidation-Reduction Pedigree Phagocytes Reactive Oxygen Species Respiratory Burst T-Lymphocytes

Alleles Animals Bacterial Proteins Bacterial Vaccines Gene Expression Regulation Bacterial Immunocompromised Host Membrane Glycoproteins Mice Mice Inbred C57BL Mice Knockout Mutation NADPH Oxidase 2 NADPH Oxidases Salmonella Infections Animal Salmonella typhimurium Virulence

Atherosclerosis Mitochondria Oxidative Stress Animals Humans Oxidative Stress Reactive Oxygen Species NADPH Oxidases antioxidants Atherosclerosis

BLM NADPH oxidase insoluble tau nifedipine voltage-gated calcium channels Amyloid beta-Peptides Animals Animals Newborn Astrocytes Calcium Calcium Channels Cell Death Coculture Techniques Gene Expression Regulation Humans NADPH Oxidases Neurons Nifedipine Oxidation-Reduction Primary Cell Culture Protein Aggregates Rats Rats Sprague-Dawley Reactive Oxygen Species Thapsigargin Verapamil tau Proteins

Context: The DUOX2 enzyme generates hydrogen peroxide (H2O2), a crucial electron acceptor for the TPO-catalyzed iodination and coupling reactions mediating thyroid hormone biosynthesis. DUOX2 mutations result in...

Codon Nonsense Cohort Studies congenital hypothyroidism Dual Oxidases Female Genetic Predisposition to Disease genetic variation Genotype Humans Infant Infant Newborn Male NADPH Oxidases Pedigree Phenotype Retrospective Studies Severity of Illness Index Thyroid Function Tests

When exposed to high light, plants produce reactive oxygen species (ROS). In Arabidopsis thaliana, local stress such as excess heat or light initiates a systemic ROS wave in phloem and xylem cells dependent on NADPH...

bundle sheath strands high light Reactive Oxygen Species rice Benzidines Carbon Dioxide Gene Expression Regulation Plant LIGHT NADPH Oxidases Oryza Oxygen Photosynthesis Plant Leaves Plant Vascular Bundle RNA Messenger Reactive Oxygen Species Transcriptome