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Results: 29
Patient survival and tumor characteristics associated with CHEK2
Taru A Muranen, Carl Blomqvist, Thilo Dörk, Anna Jakubowska, Päivi Heikkilä, Rainer Fagerholm, Dario Greco, Kristiina Aittomäki, Stig E Bojesen, Mitul Shah, Alison M Dunning, Valerie Rhenius, Per Hall, Kamila Czene, Judith S Brand, Hatef Darabi, Jenny Chang-Claude, Anja Rudolph, Børge G Nordestgaard, Fergus J Couch, Steven N Hart, Jonine Figueroa, Montserrat García-Closas, Peter A Fasching, Matthias W Beckmann, Jingmei Li, Jianjun Liu, Irene L Andrulis, Robert Winqvist, Katri Pylkäs, Arto Mannermaa, Vesa Kataja, Annika Lindblom, Sara Margolin, Jan Lubinski, Natalia Dubrowinskaja, Manjeet K Bolla, Joe Dennis, Kyriaki Michailidou, Qin Wang, Douglas F Easton, Paul DP Pharoah, Marjanka K Schmidt, Heli Nevanlinna
Nov 16, 2016
1100delC Breast Cancer CHEK2 CHK2 Gene Expression I157T Pathology survival Amino Acid Substitution Biomarkers Tumor Breast Neoplasms Checkpoint Kinase 2 Cluster Analysis Codon Europe Female Gene Expression Profiling Genetic Association Studies Heterozygote Humans Mutation Missense Neoplasm Grading Neoplasm Metastasis Neoplasm Staging Prognosis Transcriptome
A new methodologic approach for clinico-pathologic correlations in invasive placenta previa accreta.
Eric Jauniaux, Ahmed M Hussein, Nurit Zosmer, Rana M Elbarmelgy, Rasha A Elbarmelgy, Hizbullah Shaikh, Graham J Burton
Nov 27, 2019
BACKGROUND: The development of new management strategies for women presenting with placenta accreta spectrum requires quality epidemiology data, which have so far been limited by the high variability in clinical and...
Grading Histopathology increta percreta placenta previa accreta Adult blood vessels Cesarean Section dissection Female Histological Techniques Humans Hysterectomy Myometrium Pathology Photography Placenta Accreta Placenta Previa Pregnancy Prospective Studies Serous Membrane Time Factors Ultrasonography Prenatal
The NeST (neoadjuvant systemic therapy in breast cancer) study - Protocol for a prospective multi-centre cohort study to assess the current utilization and short-term outcomes of neoadjuvant systemic therapies in breast cancer.
GW Irwin, F Bannon, CE Coles, E Copson, RI Cutress, RV Dave, M Grayson, C Holcombe, S Irshad, C O'Brien, RL O'Connell, C Palmieri, AM Shaaban, N Sharma, J Singh, I Whitehead, S Potter, SA McIntosh
Feb 04, 2020
INTRODUCTION: Neoadjuvant systemic therapy (NST) has several potential advantages in the treatment of breast cancer. However, there is currently considerable variation in NST use across the UK. The NeST study is a national...
Establishing the Japan-Store House of Animal Radiobiology Experiments (J-SHARE), a large-scale necropsy and histopathology archive providing international access to important radiobiology data
Paul Schofield, Takamitsu Morioka, Benjamin Blyth, Tatsuhiko Imaoka, Mayumi Nishimura, Hiroshi Takeshita, Takeo Shimomura, Jun Ohtake, Atsuro Ishida, Paul Schofield, Bernd Grosche, Ulrike Kulka, Yutaka Yamada, Shizuko Kakinuma
Aug 09, 2019
Purpose: Projects evaluating the effects of radiation, within the National Institutes of Quantum and Radiological Science and Technology (QST), National Institute of Radiological Sciences (NIRS), have focused on risk analyses...
Animal experiments archive DATABASE Pathology tissue specimen Access to Information Animal Experimentation Animals archives Carcinogenesis Databases Factual Histology Humans Japan Medical Records Mice Neoplasms Neoplasms Radiation-Induced Program Development Radiobiology Research Research Design Risk Assessment
High Prevalence of Pre-Existing Liver Abnormalities Identified Via Autopsies in COVID-19
Yuri Hirayama, Natasha Faye Daniels, Shelley Evans, David Clarke, Stephenie Purvis, Charlotte Oliver, Stephen Woodmansey, Joy Staniforth, Elizabeth J. Soilleux
Sep 19, 2021
A high prevalence of hepatic pathology (in 17 of 19 cases) was reported in post-mortem (PM) examinations of COVID-19 patients, undertaken between March 2020 and February 2021 by a single autopsy pathologist in two English...
Development and Pathology of the Equine Mammary Gland
Katherine Hughes
Jun 26, 2021
Abstract: An understanding of the anatomy, histology, and development of the equine mammary gland underpins study of the pathology of diseases including galactorrhoea, agalactia, mastitis, and mammary tumour development. This...
High Prevalence of Pre-Existing Liver Abnormalities Identified Via Autopsies in COVID-19
Yuri Hirayama, Natasha Faye Daniels, Shelley Evans, David Clarke, Stephenie Purvis, Charlotte Oliver, Stephen Woodmansey, Joy Staniforth, Elizabeth J Soilleux
Nov 25, 2021
A high prevalence of hepatic pathology (in 17 of 19 cases) was reported in post-mortem (PM) examinations of COVID-19 patients, undertaken between March 2020 and February 2021 by a single autopsy pathologist in two English...
International Harmonization of Nomenclature and Diagnostic Criteria (INHAND)
Alys E Bradley, Lyn Miller Wancket, Matthias Rinke, Margarita M Gruebbel, Brett H Saladino, Kenneth Schafer, Osamu Katsuta, Begonya Garcia, Franck Chanut, Katherine Hughes, Keith Nelson, Lauren Himmel, Elizabeth McInnes, Adrienne Schucker, Kazuyuki Uchida
Oct 01, 2021
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain...
Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy.
Vishruti Makani, Bin Zhang, Heeoon Han, Yuemang Yao, Pierrik Lassalas, Kevin Lou, Ian Paterson, Virginia MY Lee, John Q Trojanowski, Carlo Ballatore, Amos B Smith, Kurt R Brunden
Sep 08, 2018
Neurodegenerative disorders referred to as tauopathies, which includes Alzheimer's disease (AD), are characterized by insoluble deposits of the tau protein within neuron cell bodies and dendritic processes in the brain. Tau is...
The Key Factors Predicting Dementia in Individuals With Alzheimer's Disease-Type Pathology.
Dementia affects millions of individuals worldwide, yet there are no effective treatments. Alzheimer's disease, the most common form of dementia, is characterized by amyloid and tau pathology with amyloid accumulation thought to...
Published by: Frontiers in aging neuroscience
Understanding hip pathology in ballet dancers.
Yash Singh, Matthew Pettit, Osama El-Hakeem, Rachel Elwood, Alan Norrish, Emmanuel Audenaert, Vikas Khanduja
Sep 10, 2022
PURPOSE: The literature on hip injuries in ballet dancers was systematically evaluated to answer (1) whether the prevalence of morphological abnormalities and pathology of hip injuries in dancers differs from the general...
Long-term follow-up of owned, free-roaming dogs in South Africa naturally exposed to Babesia rossi.
MK Morters, J Archer, D Ma, O Matthee, A Goddard, AL Leisewitz, PT Matjila, JLN Wood, JP Schoeman
Feb 20, 2020
Babesia rossi is an important, tick-borne intraerythrocytic protozoan parasite; however, its natural history and epidemiology is poorly understood. Babesia rossi is the most virulent Babesia sp. in domestic dogs and is generally...
Acquired immunity Babesia rossi Malaria Plasmodium South Africa Adaptive Immunity Animals Arthropod Vectors Babesia Babesiosis Dog Diseases Dogs Follow-Up Studies Longitudinal Studies Pathology Molecular Polymerase Chain Reaction Seroepidemiologic Studies Serologic Tests South Africa Tick Control Ticks
Peyton Rous
The Rockefeller University
Jan 01, 0001
Peyton Rous: A notable career in finding out
This is OCCASIONAL PAPER SIXTEEN of which fifteen hundred copies have been set in Garamond type and printed by The Rockefeller University Press in April 1971 for the family and...
Peyton Rous James S. Henderson Rous sarcoma virus Pathology Phillip D. McMaster John G. Kidd Charles Huggins
Published by: The Rockefeller University Press
The ProtecT trial
Richard J Bryant, Jon Oxley, Grace J Young, Janet A Lane, Chris Metcalfe, Michael Davis, Emma L Turner, Richard M Martin, John R Goepel, Murali Varma, David F Griffiths, Ken Grigor, Nick Mayer, Anne Y Warren, Selina Bhattarai, John Dormer, Malcolm Mason, John Staffurth, Eleanor Walsh, Derek J Rosario, James WF Catto, David E Neal, Jenny L Donovan, Freddie C Hamdy, ProtecT study group
May 19, 2020
OBJECTIVE: To test the hypothesis that the baseline clinico-pathological features of the men with localized prostate cancer (PCa) included in the ProtecT (Prostate Testing for Cancer and Treatment) trial who progressed (n = 198)...
Atypical, non-standard functions of the microtubule associated Tau protein.
Ioannis Sotiropoulos, Marie-Christine Galas, Joana M Silva, Efthimios Skoulakis, Susanne Wegmann, Mahmoud Bukar Maina, David Blum, Carmen Laura Sayas, Eva-Maria Mandelkow, Eckhard Mandelkow, Maria Grazia Spillantini, Nuno Sousa, Jesus Avila, Miguel Medina, Amrit Mudher, Luc Buee
Jan 24, 2018
Since the discovery of the microtubule-associated protein Tau (MAPT) over 40 years ago, most studies have focused on Tau's role in microtubule stability and regulation, as well as on the neuropathological consequences of Tau...
High Prevalence of Pre-Existing Liver Abnormalities Identified Via Autopsies in COVID-19
Yuri Hirayama, Natasha Faye Daniels, Shelley Evans, David Clarke, Stephenie Purvis, Charlotte Oliver, Stephen Woodmansey, Joy Staniforth, Elizabeth J Soilleux
Oct 29, 2021
A high prevalence of hepatic pathology (in 17 of 19 cases) was reported in post-mortem (PM) examinations of COVID-19 patients, undertaken between March 2020 and February 2021 by a single autopsy pathologist in two English...
A Novel Transcriptome Approach to the Investigation of the Molecular Pathology of Vitreous and Retinal Detachment.
Retinal detachment (RD) is one of the most common, sight-threatening ocular conditions requiring emergency intervention. Posterior vitreous detachment (PVD) occurs in the majority of an aging population whereby the vitreous body...
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