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Understanding the fundamentals of communication among neurons, known as neuro-spike communication, leads to reach bio-inspired nanoscale communication paradigms. In this paper, we focus on a part of neuro-spike communication...

Action Potentials Axons Cell Communication Hippocampus Models Neurological Nanotechnology Pyramidal Cells

Understanding the communication theoretical capabilities of information transmission among neurons, known as neuro-spike communication, is a significant step in developing bio-inspired solutions for nanonetworking. In this...

Action Potentials Animals Calcium Signaling Computational Biology Hippocampus Models Neurological Pyramidal Cells Synaptic Transmission Synaptic Vesicles

Fluctuation analysis is a method that allows measurement of the single-channel current of ion channels even when it is too small to be resolved directly with the patch-clamp technique. This is the case for voltage-gated calcium...

Animals Calcium Calcium Channels Dose-Response Relationship Drug Extracellular Space Models Neurological Pyramidal Cells Rats Rats Wistar

Animals Behavior Animal Brain Mapping CA3 Region Hippocampal Dependovirus Gene Silencing Halorhodopsins long-term potentiation Male Memory Mice Mice Inbred C57BL Neuronal Plasticity Pyramidal Cells Spatial Memory Synapses

15q13.3 animal model Chrna7 Cognition Copy number variation neurophysiology Prefrontal Cortex Animals Attention Deficit Disorder with Hyperactivity Behavior Animal Chromosome Deletion Chromosome Disorders Chromosomes Human Pair 15 Disease Models Animal Evoked Potentials Auditory Extinction Psychological GABA Antagonists Gene Deletion Humans Intellectual Disability Interneurons Male Mice Mice Inbred C57BL Prefrontal Cortex Pyramidal Cells Pyridazines Reaction Time Receptors GABA-A Reversal Learning Schizophrenia Schizophrenic Psychology Seizures

Recording from neural networks at the resolution of action potentials is critical for understanding how information is processed in the brain. Here, we address this challenge by developing an organic material-based...

Action Potentials Animals Cerebral Cortex Electrodes Electrophysiology Epilepsy Humans Interneurons Intraoperative Neurophysiological Monitoring Pyramidal Cells Rats

Limbic-predominant age-related TAR-DNA-binding protein-43 (TDP-43) encephalopathy with hippocampal sclerosis pathology (LATE-NC + HS) is a neurodegenerative disorder characterized by severe hippocampal CA1 neuron loss and...

ABCC9 GRN LATE-NC TDP-43 TMEM106b hippocampal sclerosis population study Aged Aged 80 and over Alleles Autopsy Brain Diseases CA1 Region Hippocampal Cohort Studies Female Genetic Predisposition to Disease Humans Male Membrane Proteins Nerve Tissue Proteins Neurodegenerative Diseases Polymorphism Single Nucleotide Progranulins Pyramidal Cells Risk Factors Sclerosis

Increasing levels of the cold-shock protein, RNA-binding motif 3 (RBM3), either through cooling or by ectopic over-expression, prevents synapse and neuronal loss in mouse models of neurodegeneration. To exploit this process...

Animals Biomarkers Brain-Derived Neurotrophic Factor Cold Temperature Membrane Glycoproteins Mice Neuroprotection Phosphorylation Prion Diseases Prions Protein Binding Protein-Tyrosine Kinases Pyramidal Cells RNA-Binding Proteins Signal Transduction Synapses

Animals Disks Large Homolog 4 Protein Electrical Synapses Hippocampus Mice Mice Knockout Mice Transgenic Microscopy NANOSTRUCTURES Protein Multimerization Pyramidal Cells Synaptic Transmission

NMDA receptor Hippocampus long-term potentiation MOUSE synaptic plasticity Animals Hippocampus Humans learning Memory Neuronal Plasticity Pyramidal Cells Synapses

There are currently a number of theories of rodent hippocampal function. They fall into two major groups that differ in the role they impute to space in hippocampal information processing. On one hand, the cognitive map theory...

cognitive map theory hippocampal units Hippocampus Memory place cells Animals Hippocampus Memory Place Cells Pyramidal Cells

Acetylcholine release in the hippocampus plays a central role in the formation of new memory representations. An influential but largely untested theory proposes that memory formation requires acetylcholine to enhance responses...

Acetylcholine Animals CA1 Region Hippocampal Carbachol Cholinergic Agonists Entorhinal Cortex Excitatory Postsynaptic Potentials Feedback Physiological Interneurons Male Mice Inbred C57BL Mice Knockout Patch-Clamp Techniques Pyramidal Cells Receptor Muscarinic M3 Synaptic Transmission