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Cover Image for Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells

Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells

W Chen, LJ Young, M Lu, A Zaccone, F Ströhl, N Yu, GS Kaminski Schierle, CF Kaminski

Feb 24, 2017

FLIM SIM Self-quenching amyloid aggregation Super-resolution

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Cover Image for Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging.

Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging.

Meng Lu, Neil Williamson, Ajay Mishra, Claire H Michel, Clemens F Kaminski, Alan Tunnacliffe, Gabriele S Kaminski Schierle

May 14, 2019

3D structure of amyloid aggregates Alzheimer's Disease arctic mutant SIM Amyloid-β amyloid-β (Aβ) microscopic imaging Molecular dynamics neurodegeneration protein aggregation structural model Amyloid beta-Peptides Humans Kinetics Microscopy Confocal Microscopy Fluorescence Models Molecular Mutation Optical Imaging Protein Conformation Protein Multimerization

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