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Results: 1
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Revealing hidden complexities of genomic rearrangements generated with Cas9.
Katharina Boroviak
,
Beiyuan Fu
,
Fengtang Yang
,
Brendan Doe
,
Allan Bradley
Oct 14, 2020
Modelling human diseases caused by large genomic rearrangements has become more accessible since the utilization of CRISPR/Cas9 in mammalian systems. In a previous study, we showed that genomic rearrangements of up to one...
Animals
CRISPR-Associated Protein 9
Female
Gene Duplication
Gene Rearrangement
Genome
In Situ Hybridization
Fluorescence
Mice
Inbred C57BL
NADPH Oxidase 4
Sequence Deletion
Sequence Inversion
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