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Results: 151
Freezing of Aqueous Solutions and Chemical Stability of Amorphous Pharmaceuticals
Evgenyi Shalaev, Alan Soper, J Axel Zeitler, Satoshi Ohtake, Christopher J Roberts, Michael J Pikal, Ke Wu, Elena Boldyreva
Sep 20, 2018
How release of phosphate from mammalian F1-ATPase generates a rotary substep.
The rotation of the central stalk of F1-ATPase is driven by energy derived from the sequential binding of an ATP molecule to its three catalytic sites and the release of the products of hydrolysis. In human F1-ATPase, each 360°...
ATP synthase Mitochondria phosphate release rotary substep Adenosine Diphosphate Animals Catalytic Domain Cattle Crystallography X-Ray Humans Hydrolysis Mitochondria Models Molecular Molecular Motor Proteins Phosphates Protein Binding Protein Structure Secondary Proton-Translocating ATPases Temperature
Ultrastructure and optics of the prism-like petal epidermal cells of Eschscholzia californica (California poppy).
Bodo D Wilts, Paula J Rudall, Edwige Moyroud, Tom Gregory, Yu Ogawa, Silvia Vignolini, Ullrich Steiner, Beverley J Glover
Aug 07, 2018
The petals of Eschscholzia californica (California poppy) are robust, pliable and typically coloured intensely orange or yellow owing to the presence of carotenoid pigments; they are also highly reflective at certain angles...
Spatial patterns and broad-scale weather cues of beech mast seeding in Europe.
Giorgio Vacchiano, Andrew Hacket-Pain, Marco Turco, Renzo Motta, Janet Maringer, Marco Conedera, Igor Drobyshev, Davide Ascoli
Dec 12, 2017
Mast seeding is a crucial population process in many tree species, but its spatio-temporal patterns and drivers at the continental scale remain unknown . Using a large dataset (8000 masting observations across Europe for years...
Controlled Oil/Water Partitioning of Hydrophobic Substrates Extending the Bioanalytical Applications of Droplet-Based Microfluidics.
Tomas Buryska, Michal Vasina, Fabrice Gielen, Pavel Vanacek, Liisa van Vliet, Jan Jezek, Zdenek Pilat, Pavel Zemanek, Jiri Damborsky, Florian Hollfelder, Zbynek Prokop
Jun 27, 2019
Temperature and pH-responsive nano-hydrogel drug delivery system based on lysine-modified poly (vinylcaprolactam).
Fatemeh Farjadian, Somayeh Rezaeifard, Mahsa Naeimi, Sahar Ghasemi, Soliman Mohammadi-Samani, Mark E Welland, Lobat Tayebi
Oct 28, 2019
BACKGROUND: Smart materials capable of responding to external stimuli are noteworthy candidates in designing drug delivery systems. In many of the recent research, temperature and pH have been recognized as the main stimulating...
DOX PVCL Raft Cancer Drug delivery Lysine Caprolactam Cell Death Doxorubicin Drug Carriers Drug Delivery Systems Drug Liberation Humans Hydrogels Hydrogen-Ion Concentration Lysine MCF-7 Cells Molecular Weight Nanoparticles Phase Transition Polymers Proton Magnetic Resonance Spectroscopy spectroscopy Fourier Transform Infrared Temperature Toxicity Tests
Temperature-Dependent Reproductive Enhancement of the Pea Aphid from Mutualistic Infection by the Symbiont Hamiltonella defensa
Ian T. Abrahams
Jan 01, 0001
Symbiosis between eukaryotes and prokaryotes is ubiquitous and has contributed to the origin of eukaryotes. Insects are the most abundant multicellular organisms and engage in symbiosis with diverse microbes, ranging from...
Published by: Ursinus College
Responsive Double Network Hydrogels of Interpenetrating DNA and CB[8] Host-Guest Supramolecular Systems.
Chuang Li, Matthew J Rowland, Yu Shao, Tianyang Cao, Chun Chen, Haoyang Jia, Xu Zhou, Zhongqiang Yang, Oren A Scherman, Dongsheng Liu
Jun 01, 2015
Analyzing seasonality of tuberculosis across Indian states and union territories.
A significant seasonal variation in tuberculosis (TB) is observed in north India during 2006-2011, particularly in states like Himachal Pradesh, Haryana and Rajasthan. To quantify the seasonal variation, we measure average...
Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model.
Tatsuya Shonaka, Naoto Matsuno, Hiromichi Obara, Ryo Yoshikawa, Yuji Nishikawa, Yo Ishihara, Hiroki Bochimoto, Mikako Gochi, Masahide Otani, Hiroyuki Kanazawa, Hiroshi Azuma, Hiromi Sakai, Hiroyuki Furukawa
Dec 11, 2019
The recent clinical application of perfusion technology for the machine preservation of donation after cardiac death (DCD) grafts has some advantages. Oxygenation has been proposed for the preservation of DCD liver grafts. The...
Adenosine allopurinol Animals Aspartate Aminotransferases Female Glutathione Hemoglobins Hepatic Artery Humans Hydrogen-Ion Concentration Insulin Lactic Acid Liver Liver Transplantation Mitochondria Models Animal Organ Preservation Organ Preservation Solutions Oxygen Oxygen Consumption Raffinose Swine Temperature
Plants in the UK flower a month earlier under recent warming.
Global temperatures are rising at an unprecedented rate, but environmental responses are often difficult to recognize and quantify. Long-term observations of plant phenology, the annually recurring sequence of plant...
Benefits of protected areas for nonbreeding waterbirds adjusting their distributions under climate warming.
Elie Gaget, Diego Pavón-Jordán, Alison Johnston, Aleksi Lehikoinen, Wesley M Hochachka, Brett K Sandercock, Alaaeldin Soultan, Hichem Azafzaf, Nadjiba Bendjedda, Taulant Bino, Luka Božič, Preben Clausen, Mohamed Dakki, Koen Devos, Cristi Domsa, Vitor Encarnação, Kiraz Erciyas-Yavuz, Sándor Faragó, Teresa Frost, Clemence Gaudard, Lívia Gosztonyi, Fredrik Haas, Menno Hornman, Tom Langendoen, Christina Ieronymidou, Vasiliy A Kostyushin, Lesley J Lewis, Svein-Håkon Lorentsen, Leho Luigujõe, Włodzimierz Meissner, Tibor Mikuska, Blas Molina, Zuzana Musilová, Viktor Natykanets, Jean-Yves Paquet, Nicky Petkov, Danae Portolou, Jozef Ridzoň, Samir Sayoud, Marko Šćiban, Laimonas Sniauksta, Antra Stīpniece, Nicolas Strebel, Norbert Teufelbauer, Goran Topić, Danka Uzunova, Andrej Vizi, Johannes Wahl, Marco Zenatello, Jon E Brommer
May 27, 2021
Climate warming is driving changes in species distributions and community composition. Many species have a so-called climatic debt, that is, shifts in range lag behind shifts in temperature isoclines. Inside protected areas...
ajuste comunitario cambio de distribución colonización colonization community adjustment community temperature index extinción Extinction humedales range shift wetlands índice de temperatura comunitaria 定殖 湿地 灭绝 群落温度指数 群落调整 范围变化 Animals Biodiversity Birds climate change Conservation of Natural Resources Ecosystem Temperature
Equilibrium Constants of Various Polyol-borate Systems
Karen L. Wanner
Jan 01, 0001
This 26 page thesis examines the polyol-borate system.
polyols borates equilibrium constants ionic strength Temperature Glycerol Chemistry Physical Sciences and Mathematics
Published by: Ursinus College
Receptor-type Guanylyl Cyclases Confer Thermosensory Responses in C. elegans.
Asuka Takeishi, Yanxun V Yu, Vera M Hapiak, Harold W Bell, Timothy O'Leary, Piali Sengupta
Feb 23, 2016
The Disintegration Process in Microcrystalline Cellulose Based Tablets, Part 1
Samy Yassin, Daniel J Goodwin, Andrew Anderson, Juraj Sibik, D Ian Wilson, Lynn F Gladden, J Axel Zeitler
Jun 17, 2015
formulation polymeric drug delivery systems Porosity solid dosage forms structure-transport relationship superdisintegrants swelling terahertz pulsed imaging Algorithms Cellulose Chemistry Pharmaceutical Dosage Forms Drug Delivery Systems excipients Kinetics Models Theoretical Porosity Solubility Tablets Temperature
The effect of the type of HA on the degradation of PLGA/HA composites.
Buffering effects Hydroxyapatite Particle-mediated water sorption Poly(d l lactide-co-glycolide (50:50)) Calcium Durapatite Elastic Modulus Hydrogen-Ion Concentration Lactic Acid Molecular Weight Particle Size Polyglycolic Acid Polylactic Acid-Polyglycolic Acid Copolymer Powders Solutions Temperature water X-Ray Diffraction
Functional hybrid rubisco enzymes with plant small subunits and algal large subunits
Algal Proteins Arabidopsis Base Sequence Blotting Western Chlamydomonas DNA Complementary Enzyme Stability Gene Expression Regulation Enzymologic Helianthus Kinetics Microscopy Electron Molecular Sequence Data Mutation Photosynthesis Plant Proteins Plasmids Protein Engineering Protein Subunits Recombinant Fusion Proteins Ribulose-Bisphosphate Carboxylase Temperature Transformation Genetic
Linking warming effects on phenology, demography, and range expansion in a migratory bird population.
Phenological changes in response to climate change have been recorded in many taxa, but the population-level consequences of these changes are largely unknown. If phenological change influences demography, it may underpin the...
Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold.
Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a series of enzyme active sites. Many...
Attempt to correlate simulations and measurements of turbine performance under pulsating flows for automotive turbochargers
The paper attempts to correlate simulations and measurements of turbine performance under pulsating flows for automotive turbochargers. Under real automotive powertrain conditions, turbochargers are subjected to pulsating...
Coarse-Grained Simulations Complemented by Atomistic Molecular Dynamics Provide New Insights into Folding and Unfolding of Human Telomeric G-Quadruplexes.
Petr Stadlbauer, Liuba Mazzanti, Tristan Cragnolini, David J Wales, Philippe Derreumaux, Samuela Pasquali, Jiří Šponer
Feb 15, 2019
G-quadruplexes are the most important noncanonical DNA architectures. Many quadruplex-forming sequences, including the human telomeric sequence d(GGGTTA)n, have been investigated due to their implications in cancer and other...
Pressure and Chemical Unfolding of an α-Helical Bundle Protein
Cécile Dubois, Vicente J Planelles-Herrero, Camille Tillatte-Tripodi, Stéphane Delbecq, Léa Mammri, Elena M Sirkia, Virginie Ropars, Christian Roumestand, Philippe Barthe
Mar 31, 2021
When combined with NMR spectroscopy, high hydrostatic pressure is an alternative perturbation method used to destabilize globular proteins that has proven to be particularly well suited for exploring the unfolding energy...
NMR high hydrostatic pressure Protein Folding Thermodynamic stability α-helical bundle Adaptor Proteins Signal Transducing Humans Kinetics Magnetic Resonance Spectroscopy Models Molecular Protein Conformation Protein Conformation alpha-Helical Protein Denaturation Protein Domains Protein Unfolding Temperature Thermodynamics
The impact of climate and antigenic evolution on seasonal influenza virus epidemics in Australia.
Although seasonal influenza viruses circulate globally, prevention and treatment occur at the level of regions, cities, and communities. At these scales, the timing, duration and magnitude of epidemics vary substantially, but...
Warming-induced tipping points of Arctic and alpine shrub recruitment.
Shrub recruitment, a key component of vegetation dynamics beyond forests, is a highly sensitive indicator of climate and environmental change. Warming-induced tipping points in Arctic and alpine treeless ecosystems are, however...
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