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Results: 24
Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Jacinta I Kalisch-Smith, Nikita Ved, Dorota Szumska, Jacob Munro, Michael Troup, Shelley E Harris, Helena Rodriguez-Caro, Aimée Jacquemot, Jack J Miller, Eleanor M Stuart, Magda Wolna, Emily Hardman, Fabrice Prin, Eva Lana-Elola, Rifdat Aoidi, Elizabeth MC Fisher, Victor LJ Tybulewicz, Timothy J Mohun, Samira Lakhal-Littleton, Sarah De Val, Eleni Giannoulatou, Duncan B Sparrow
Jul 28, 2021
Congenital heart disease (CHD) is the most common class of human birth defects, with a prevalence of 0.9% of births. However, two-thirds of cases have an unknown cause, and many of these are thought to be caused by in utero...
Animals Aorta Thoracic Biomarkers cardiovascular system Cell Differentiation Coronary Vessels Dietary Supplements Edema Embryo Mammalian Embryonic Development Female Gene Expression Profiling Gene-Environment Interaction Green Fluorescent Proteins Iron Iron Deficiencies Lymphatic Vessels Mice Inbred C57BL Myocardium Myocytes Cardiac Penetrance Phenotype Pregnancy Signal Transduction Stem Cells Transgenes Tretinoin
C5a anaphylatoxin and its role in critical illness-induced organ dysfunction.
Alexander Jt Wood, Arlette Vassallo, Charlotte Summers, Edwin R Chilvers, Andrew Conway-Morris
Nov 19, 2018
C5a complement Critical Illness immunosuppression Infection neutrophil Anaphylatoxins Blood Coagulation Blood Platelets cardiovascular system Cell Communication Complement C5a Critical Illness Endothelium Vascular Humans Immune System Diseases Immunity Innate Multiple Organ Failure Receptor Anaphylatoxin C5a
Hypertension Programmed in Adult Hens by Isolated Effects of Developmental Hypoxia In Ovo.
Katie L Skeffington, Christian Beck, Nozomi Itani, Youguo Niu, Caroline J Shaw, Dino A Giussani
May 11, 2020
Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals.
Human epidemiological and animal studies have revealed the long-term effects of malnutrition during gestation and early life on the health of the offspring. The aim of the current review is to survey the different means of...
Maternal and fetal cardiovascular and metabolic effects of intra-operative uterine handling under general anesthesia during pregnancy in sheep.
Effects of 4-Week Lifestyle Intervention on Cardiovascular Health and Fitness Levels of Adults
Tia R. Wisdo
Jan 01, 0001
Cardiovascular disease (CVD) has been identified as a leading cause of death in the United States, with more than two million Americans having a heart attack or a stroke and close to a million deaths each year. Research shows...
Cardiovascular Exercise Intervention FITNESS HEALTH Body Mass Index blood cholesterol Blood Glucose Cardiology Cardiovascular Diseases cardiovascular system Exercise Physiology Medicine and Health Sciences
Published by: Ursinus College
The Morphology and Contractility of the Postpartum Heart
Aaron R. Nelson
Jan 01, 0001
The female heart has previously been found to adapt to physiological stresses, one being pregnancy and the structural and hemodynamic adaptations that the female heart undergoes prior to delivery. Due to hormonal and hemodynamic...
pregnancy-induced hypertrophy pathological hypertrophy physiological hypertrophy Postpartum morphological adaptations contractile function Biology cardiovascular system Life Sciences
Published by: Ursinus College
The Effects of Multiple Pregnancies on the Murine Heart: Are Changes in Pregnancy-Induced Cardiac Function Exacerbated After Multiple Pregnancies?
Marcus J Wagner
Jan 01, 0001
Hypertrophy, or the enlargement of the heart, can be induced in two forms. A physiological hypertrophy occurs when the heart becomes stronger and can handle increased blood volume and pressure loads because of an increase in...
Pregnancy Mice Murine Heart cardiac hypertrophy Multiparous physiological pathological Biology cardiovascular system Life Sciences translational medical research
Published by: Ursinus College
Carotid Artery IMT, Blood Pressure, and Cardiovascular Risk Factors in Males and Females
Christina M Cromwell
Jan 01, 0001
Previous studies have investigated carotid artery intima-media thickness (IMT) and blood pressure and found a direct correlation between the two. Also, studies have examined IMT and blood glucose and cholesterol levels. It is...
blood pressure intima-media thickness Cardiovascular Cholesterol vascular health Glucose Cardiovascular Diseases cardiovascular system Circulatory and Respiratory Physiology Medicine and Health Sciences
Published by: Ursinus College
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology.
Alessandra Stangherlin, Joseph L Watson, David CS Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D Beale, Edward A Hayter, Alina Guna, Alison J Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M Voorhees, David A Bechtold, Emmanuel Derivery, Rachel S Edgar, Peter Newham, John S O'Neill
Dec 15, 2021
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic...
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.
Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K Hedman, Andrew Schork, Karen Page, Daria V Zhernakova, Yang Wu, James Peters, Niclas Eriksson, Sarah E Bergen, Thibaud S Boutin, Andrew D Bretherick, Stefan Enroth, Anette Kalnapenkis, Jesper R Gådin, Bianca E Suur, Yan Chen, Ljubica Matic, Jeremy D Gale, Julie Lee, Weidong Zhang, Amira Quazi, Mika Ala-Korpela, Seung Hoan Choi, Annique Claringbould, John Danesh, George Davey Smith, Federico De Masi, Sölve Elmståhl, Gunnar Engström, Eric Fauman, Celine Fernandez, Lude Franke, Paul W Franks, Vilmantas Giedraitis, Chris Haley, Anders Hamsten, Andres Ingason, Åsa Johansson, Peter K Joshi, Lars Lind, Cecilia M Lindgren, Steven Lubitz, Tom Palmer, Erin Macdonald-Dunlop, Martin Magnusson, Olle Melander, Karl Michaelsson, Andrew P Morris, Reedik Mägi, Michael W Nagle, Peter M Nilsson, Jan Nilsson, Marju Orho-Melander, Ozren Polasek, Bram Prins, Erik Pålsson, Ting Qi, Marketa Sjögren, Johan Sundström, Praveen Surendran, Urmo Võsa, Thomas Werge, Rasmus Wernersson, Harm-Jan Westra, Jian Yang, Alexandra Zhernakova, Johan Ärnlöv, Jingyuan Fu, J Gustav Smith, Tõnu Esko, Caroline Hayward, Ulf Gyllensten, Mikael Landen, Agneta Siegbahn, James F Wilson, Lars Wallentin, Adam S Butterworth, Michael V Holmes, Erik Ingelsson, Anders Mälarstig
Nov 26, 2020
Circulating proteins are vital in human health and disease and are frequently used as biomarkers for clinical decision-making or as targets for pharmacological intervention. Here, we map and replicate protein quantitative trait...
ATP Binding Cassette Transporter 1 Asthma cardiovascular system Chromosome Mapping Drug Delivery Systems Gene Knockdown Techniques Genome-Wide Association Study Genomics Humans Inflammatory Bowel Diseases Interleukin-1 Receptor-Like 1 Protein Intracellular Signaling Peptides and Proteins Linkage Disequilibrium Mendelian Randomization Analysis Protein Serine-Threonine Kinases Proteome Quantitative Trait Loci Receptors CCR2 Receptors CCR5
Cardiovascular and enjoyment comparisons after active videogame and running in type 1 diabetes patients
Jorge Luiz de Brito Gomes, Denise Maria Martins Vancea, Rodrigo Cappato de Araújo, Pooya Soltani, Fernando José de Sá Pereira Guimarães, Manoel da Cunha Costa
Oct 31, 2021
Background: Active videogames (AVGs) have been primarily studied in healthy individuals. To use the technology in type 1 diabetes mellitus (T1DM) patients, cardiovascular and enjoyment responses should be studied and compared...
cardiovascular system Diabetes mellitus Exercise motivation Running Videogames /dk/atira/pure/subjectarea/asjc/3300/3306 name=Health(social science) /dk/atira/pure/subjectarea/asjc/2700/2742 name=Rehabilitation /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Cardiovascular and enjoyment comparisons after active videogame and running in type 1 diabetes patients
Jorge Luiz de Brito Gomes, Denise Maria Martins Vancea, Rodrigo Cappato de Araújo, Pooya Soltani, Fernando José de Sá Pereira Guimarães, Manoel da Cunha Costa
Oct 31, 2021
Background: Active videogames (AVGs) have been primarily studied in healthy individuals. To use the technology in type 1 diabetes mellitus (T1DM) patients, cardiovascular and enjoyment responses should be studied and compared...
cardiovascular system Diabetes mellitus Exercise motivation Running Videogames /dk/atira/pure/subjectarea/asjc/3300/3306 name=Health(social science) /dk/atira/pure/subjectarea/asjc/2700/2742 name=Rehabilitation /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human
JJ Maguire, HR Kirby, EJ Mead, RE Kuc, X d'Anglemont de Tassigny, WH Colledge, AP Davenport
Apr 10, 2017
Adolescent Adult Aged Animals Aorta Cardiotonic Agents cardiovascular system Endothelium Vascular Female Gene Expression Regulation Heart Atria Heart Diseases Humans In Vitro Techniques Kisspeptins Male Mice Middle Aged Myocardium Myocytes Cardiac Protein Transport Puberty RNA Messenger Rats Receptors Cell Surface Vasoconstriction Young Adult
Blood Pressure of Firefighters and Emergency Medical Technicians (EMT) in Response to Emergency Calls
Cassandra C Derella
Jan 01, 0001
High levels of stress can lead to a higher resting blood pressure (BP) eventually leading to hypertension and increased risks for cardiovascular disease (CVD). Sources of stress can be a result of many factors but often stem...
Firefighters blood pressure emergency medical technician cardiovascular disease cardiovascular system Medicine and Health Sciences
Published by: Ursinus College
Early Asymmetric Cardio-Cerebral Causality and Outcome after Severe Traumatic Brain Injury.
The role of epoxyeicosatrienoic acids in the cardiovascular system.
Workshop to identify critical windows of exposure for children's health
The work group on cardiovascular and endocrine effects was asked to review the current state of knowledge about children's windows of vulnerability to developmental toxicants and to recommend how that information may be used to...
Neonatal glucocorticoid overexposure alters cardiovascular function in young adult horses in a sex-linked manner.
Orlando A Valenzuela, Juanita K Jellyman, Vanessa L Allen, Youguo Niu, Nicola B Holdstock, Alison J Forhead, Dino A Giussani, Abigail L Fowden, Emilio A Herrera
Apr 30, 2020
Combined Effects of Obesity and Pregnancy on Cardiac Function
Andrea Cando
Jan 01, 0001
Obesity has been linked to many cardiovascular disorders such as heart disease and diabetes. The development of obesity predominantly derives from a sedentary lifestyle and a high-fat diet (HFD). Cardiovascular disorders have...
Published by: Ursinus College
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Duuamene Nyimanu, Fiona A Chapman, Peter J Gallacher, Rhoda E Kuc, Thomas L Williams, David E Newby, Janet J Maguire, Anthony P Davenport, Neeraj Dhaun
Jul 20, 2022
AIMS: Chronic kidney disease (CKD) is common and cardiovascular disease (CVD) is its commonest complication. The apelin system is a potential therapeutic target for CVD but data relating to apelin in CKD are limited. We examined...