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SOX9 Cell of origin collagen IV Extracellular Matrix Histopathology in vivo models metastasis Non-Small Cell Lung Cancer Animals Carcinoma Non-Small-Cell Lung Disease Progression Humans Lung Neoplasms Mice SOX9 Transcription Factor

Neurodegenerative disorders, including Alzheimer's (AD) and Parkinson's diseases (PD), are characterised by the formation of aberrant assemblies of misfolded proteins. The discovery of disease-modifying drugs for these disorders...

Alzheimer's Disease Parkinson's Disease biophysical methods in vivo models protein misfolding Alzheimer Disease Amyloid beta-Peptides Animals Animals Genetically Modified Disease Models Animal Gene Expression Parkinson Disease Protein Aggregates Protein Folding ALPHA-SYNUCLEIN tau Proteins

RPL24 cancer biology Cell Biology eEF2K in vivo models Intestinal cancer MOUSE protein sythesis Translation Animals Colorectal Neoplasms Disease Models Animal Elongation Factor 2 Kinase Female Male Mice Mice Transgenic Mutation Phosphorylation Ribosomal Proteins Signal Transduction

RESEARCH ARTICLE cancer biology Cell Biology Translation protein sythesis Intestinal cancer in vivo models RPL24 eEF2K MOUSE

Through advances in the past decades, the central role of aberrant protein aggregation has been established in many neurodegenerative diseases. Crucially, however, the molecular mechanisms that underlie aggregate proliferation...

Amyloid chemical kinetics in vivo models Mechanistic models Neurodegenerative disease protein aggregation