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Evolutionary plasticity in the allosteric regulator-binding site of pyruvate kinase isoform PykA from Pseudomonas aeruginosa.
Yassmin Abdelhamid, Paul Brear, Jack Greenhalgh, Xavier Chee, Taufiq Rahman, Martin Welch
Aug 29, 2019
Entner-Doudoroff Pathway Pseudomonas Pseudomonas aeruginosa PykA X-ray crystallography allostery bacterial metabolism Glycolysis pentose phosphate pathway (PPP) Pyruvate Kinase Allosteric Regulation Allosteric Site Bacterial Proteins Catalytic Domain Glucose-6-Phosphate Isoenzymes Models Molecular pentose phosphate pathway Pseudomonas aeruginosa Pyruvate Kinase
The return of metabolism
Anna Stincone, Alessandro Prigione, Thorsten Cramer, Mirjam MC Wamelink, Kate Campbell, Eric Cheung, Viridiana Olin-Sandoval, Nana-Maria Grüning, Antje Krüger, Mohammad Tauqeer Alam, Markus A Keller, Michael Breitenbach, Kevin M Brindle, Joshua D Rabinowitz, Markus Ralser
Sep 08, 2014
NADPH Cancer glucose 6‐phosphate dehydrogenase Glycolysis host–pathogen interactions inherited metabolic disease Metabolic Engineering metabolism of infection Metabolomics Oxidative Stress parasitic protozoa pentose phosphate pathway Stem Cells Humans Metabolic Diseases metabolism Pentose Phosphate Pathway
Glycolysis and the pentose phosphate pathway after human traumatic brain injury
Ibrahim Jalloh, Keri LH Carpenter, Peter Grice, Duncan J Howe, Andrew Mason, Clare N Gallagher, Adel Helmy, Michael P Murphy, David K Menon, T Adrian Carpenter, John D Pickard, Peter J Hutchinson
Sep 15, 2014
Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.
Gabriel Piedrafita, Sreejith J Varma, Cecilia Castro, Christoph B Messner, Lukasz Szyrwiel, Julian L Griffin, Markus Ralser
Jan 05, 2022
The structure of the metabolic network is highly conserved, but we know little about its evolutionary origins. Key for explaining the early evolution of metabolism is solving a chicken-egg dilemma, which describes that enzymes...
Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus
Karla D Passalacqua, Jia Lu, Ian Goodfellow, Abimbola O Kolawole, Jacob R Arche, Robert J Maddox, Kelly E Carnahan, Mary XD O’Riordan, Christiane E Wobus
Mar 14, 2019
calicivirus carbon metabolism Glycolysis noroviruses Oxidative Phosphorylation pentose phosphate pathway Animals Caco-2 Cells Caliciviridae Infections Glycolysis Host-Pathogen Interactions Humans MACROPHAGES Metabolomics Mice Norovirus Oxidative Phosphorylation pentose phosphate pathway RAW 264.7 Cells Virus Replication
The Pentose Phosphate Pathway Regulates the Circadian Clock.
Guillaume Rey, Utham K Valekunja, Kevin A Feeney, Lisa Wulund, Nikolay B Milev, Alessandra Stangherlin, Laura Ansel-Bollepalli, Vidya Velagapudi, John S O'Neill, Akhilesh B Reddy
Sep 22, 2016
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
13C acetate Energy Metabolism Glucose Glycolysis Mitochondria Oligodendroglia pyruvate carboxylation Acetates Acetyl Coenzyme A Animals Carbon Radioisotopes Cells Cultured Citric Acid Cycle Cytosol Glucose Lactic Acid Malates Mitochondria Neural Stem Cells Oligodendroglia Oxaloacetic Acid pentose phosphate pathway Phosphoenolpyruvate Pyruvic Acid Radiopharmaceuticals Rats Sprague-Dawley
A haploproficient interaction of the transaldolase paralogue NQM1 with the transcription factor VHR1 affects stationary phase survival and oxidative stress resistance.
Contextual Flexibility in Pseudomonas aeruginosa Central Carbon Metabolism during Growth in Single Carbon Sources.
Stephen K Dolan, Michael Kohlstedt, Stephen Trigg, Pedro Vallejo Ramirez, Clemens F Kaminski, Christoph Wittmann, Martin Welch
Feb 12, 2020