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D. melanogaster developmental biology Optic Lobe physics of living systems proneural wave reaction-diffusion system sequential patterning Animals Cell Differentiation Drosophila Drosophila Proteins ErbB Receptors Gene Expression Regulation Developmental Neuroepithelial Cells Neurons Optic Lobe Nonmammalian Receptors Invertebrate Peptide Signal Transduction

The prevalence of multicellular organisms is due in part to their ability to form complex structures. How cells pack in these structures is a fundamental biophysical issue, underlying their functional properties. However, much...

S. cerevisiae Snowflake yeast Volvox Entropy multicellularity physics of living systems Cell Size Directed Molecular Evolution Phylogeny Volvox Yeasts

Suction is widely used by animals for strong controllable underwater adhesion but is less well understood than adhesion of terrestrial climbing animals. Here we investigate the attachment of aquatic insect larvae...

RESEARCH ARTICLE Ecology physics of living systems biomechanics Adhesion underwater adhesion aquatic invertebrate Surface roughness Other

actin Cytoskeleton mathematical modeling Microtubules molecular motors None physics of living systems Actomyosin Computer Simulation Cytoskeleton Microtubules Models Biological Molecular Motor Proteins

developmental biology Diffusion interkinetic nuclear migration nuclear crowding physics of living systems Zebrafish Animals Cell Movement Cell Nucleus Diffusion Embryo Nonmammalian Retina Zebrafish

Suction is widely used by animals for strong controllable underwater adhesion but is less well understood than adhesion of terrestrial climbing animals. Here we investigate the attachment of aquatic insect larvae...

Adhesion aquatic invertebrate biomechanics Ecology physics of living systems Surface roughness underwater adhesion Adhesiveness Animals aquatic organisms Biomechanical Phenomena Larva Nematocera rivers

Tissue mechanics is important for development; however, the spatio-temporal dynamics of in vivo tissue stiffness is still poorly understood. We here developed tiv-AFM, combining time-lapse in vivo atomic force microscopy with...

Atomic force microscopy Axon guidance developmental biology durotaxis Mechanics Mechanotransduction physics of living systems Stiffness Xenopus Animals Axons Biomechanical Phenomena Brain Cell Body Cell Count Embryo Nonmammalian Mitosis Optic Tract Retinal Ganglion Cells Xenopus laevis

RESEARCH ARTICLE developmental biology physics of living systems nuclear crowding Diffusion interkinetic nuclear migration Zebrafish

Spermatozoa of marine invertebrates are attracted to their conspecific female gamete by diffusive molecules, called chemoattractants, released from the egg investments in a process known as chemotaxis. The information from the...

cell motility Fertilization physics of living systems sperm chemotaxis Animals Calcium Calcium Signaling Chemotactic Factors Chemotaxis Male Oligopeptides Ovum Receptors Cell Surface Sea Urchins Species Specificity Sperm Motility Sperm Tail Spermatozoa Strongylocentrotus purpuratus

One of the great challenges in biology is to understand the mechanisms by which morphogenetic processes arise from molecular activities. We investigated this problem in the context of actomyosin-based cortical flow in C. elegans...

C. elegans RNAi screen Actomyosin Cell Biology cortical flow degeneracy hydrodynamics physics of living systems Actins Actomyosin Animals Caenorhabditis elegans Caenorhabditis elegans Proteins Embryo Nonmammalian Fluorescence hydrodynamics Microfilament Proteins Models Biological Morphogenesis Myosins RNA Interference Rheology

D. melanogaster Axons microtubule orientation microtubule polarity Neurons physics of living systems Animals Axons Drosophila melanogaster Dyneins Microtubules Neurons

The prevalence of multicellular organisms is due in part to their ability to form complex structures. How cells pack in these structures is a fundamental biophysical issue, underlying their functional properties....

RESEARCH ARTICLE physics of living systems multicellularity Snowflake yeast Volvox Entropy S. cerevisiae Other

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Interdisciplinary Research mathematical modeling Physics physics of living systems scientific publishing Theory Humans Models Theoretical

Artificial Intelligence Cell Biology kymograms kymographs Machine Learning Neurons None physics of living systems transport Automation Laboratory Deep learning Kymography Software

Magnetococcus marinus dark-field microscopy magnetotactic bacteria microswimmer path tracking physics of living systems Alphaproteobacteria Flagella hydrodynamics Models Biological Movement Rotation

RESEARCH ARTICLE physics of living systems Axons Neurons microtubule orientation microtubule polarity D. melanogaster

During dynamic instability, self-assembling microtubules (MTs) stochastically alternate between phases of growth and shrinkage. This process is driven by the presence of two distinct states of MT subunits, GTP- and GDP-bound...

Dynamic instability Kinetics microtubule None physics of living systems Computer Simulation Guanosine Diphosphate Guanosine Triphosphate Kinetics Microtubules Models Molecular Protein Binding Tubulin