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Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation.
Fay M Allen, Ana SH Costa, Anja V Gruszczyk, Georgina R Bates, Hiran A Prag, Efterpi Nikitopoulou, Carlo Viscomi, Christian Frezza, Andrew M James, Michael P Murphy
Oct 27, 2022
The compartmentation and distribution of metabolites between mitochondria and the rest of the cell is a key parameter of cell signalling and pathology. Here, we have developed a rapid fractionation procedure that enables us to...