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Factors influencing Raynaud condition score diary outcomes in systemic sclerosis
Objective. Raynaud phenomenon (RP) in systemic sclerosis (SSc) could be influenced by clinical phenotype, environmental factors (e.g., season), and personal factors (e.g., coping strategies and ill-health perceptions). We...
Bioquality Hotspots in the Tropical African Flora.
Identifying areas of high biodiversity is an established way to prioritize areas for conservation [1-3], but global approaches have been criticized for failing to render global biodiversity value at a scale suitable for local...
Implications of the prevalence and magnitude of sustained declines for determining a minimum threshold for favourable population size.
We propose a new approach to quantifying a minimum threshold value for the size of an animal population, below which that population might be categorised as having unfavourable status. Under European Union law, the concept of...
Implications of the prevalence and magnitude of sustained declines for determining a minimum threshold for favourable population size.
We propose a new approach to quantifying a minimum threshold value for the size of an animal population, below which that population might be categorised as having unfavourable status. Under European Union law, the concept of...
Published by: PLOS ONE
The Role of Vascular Endothelial Growth Factor in Systemic Sclerosis
The pathological hallmarks of Systemic sclerosis (SSc) constitute an inter-related triad of autoimmunity, vasculopathy and tissue remodeling. Many signaling mediators have been implicated in SSc pathology; most focusing on...
Structure based drug design of angiotensin-i converting enzyme inhibitors
Cardiovascular disease (CVD) is responsible for ̃27% of deaths worldwide, with 80% of these occuring in developing countries. Hypertension is one of the most important treatable factors in the prevention of CVD. Angiotensin-I...
The Ursinus Weekly, January 10, 1916
University of Pennsylvania society debates Schaff Ursinus victim; Albright victor Death of Albert Vogel College spirit Christian associations Resolutions Inter-group basketball
Ursinus College Collegeville Pennsylvania newspaper Dwight O. Kerr Basketball Schaff literary society YMCA YWCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, February 26, 1940
"Design for understanding" is all-Ursinus conference theme Mr. Bailey improved Jan Peerce interview reveals past hardships, future plans Old England scene of pageant May 11 Dr. Philip reviews Jan Peerce concert Leads for...
Ursinus College Collegeville Pennsylvania newspaper May Day pageant Jan Peerce John Hart Ruby Henry L. Deimel Harvey L. Carter debate team International Relations Club John B. Price freshmen customs Basketball wrestling cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus
Several prior reports have identified peptides that are naturally associated with major histocompatibility complex (MHC) class II molecules on presenting cells. We have examined the delivery of a peptide from exogenous sources...
antigen presenting cell hybridoma Influenza virus major histocompatibility complex restriction protein isolation t lymphocyte activation
Published by: Rockefeller University
Enantioselective Intermolecular C-H Amination Directed by a Chiral Cation.
The enantioselective amination of C(sp3)-H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the...
Published by: Journal of the American Chemical Society
Retinal Ganglion Cells-Diversity of Cell Types and Clinical Relevance.
Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the visual processing centres within the central nervous system. There is a remarkable diversity of RGCs and the various subtypes have...
Epidemiology of systemic sclerosis in the UK
OBJECTIVES: We developed and tested a robust case ascertainment strategy within the Clinical Practice Research Datalink (CPRD), with the aim of assessing the incidence, prevalence, mortality and delay in diagnosis of SSc in...
Antibody Surface Coverage Drives Matrix Interference in Microfluidic Capillary Immunoassays
The performance of biosensors is often optimized in buffers, which brings inconsistencies during applications with biological samples. Current strategies for minimizing sample (matrix) interference are complex to automate and...
A mutual information approach to automate identification of neuronal clusters in Drosophila brain images.
Mapping neural circuits can be accomplished by labeling a small number of neural structures per brain, and then combining these structures across multiple brains. This sparse labeling method has been particularly effective in...
Human NDE1 splicing and mammalian brain development.
Exploring genetic and molecular differences between humans and other close species may be the key to explain the uniqueness of our brain and the selective pressures under which it evolves. Recent discoveries unveiled the...
Hollow-fiber membrane technology
Dermal bioavailability is currently estimated through skin penetration studies using ex vivo models, which lack any measure of capillary bed function, and thus do not fully reproduce physiological conditions. We propose a novel...
Optimizing the Cross-sectional Shapes of Extruded Aluminium Structural Members for Unitized Curtain Wall Facades
Curtain walls are lightweight, weathertight, exterior facades. They are capable of resisting wind loads, but provide no support for the building it to which they are attached. Although they are used to enclose many different...
Lightning parameters of sprites and diameter of halos over South Africa
Transient Luminous Events (TLEs) above thunderclouds have been previously associated with variables such as the lightning Charge Moment Change (CMC), charge height, charge transfer, and lightning current rise-time. We show...
Development and field trial of a driver assistance system to encourage eco-driving in light commercial vehicle fleets
Driver training schemes and eco-driving techniques can reduce fuel
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
consumption by 10% but their effectiveness depends on the willingness of drivers to change their behaviour, and changes may be short lived. On board driver...
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