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Results: 12748
GRB 171010A/SN 2017htp
Andrea Melandri, D.B. Malesani, L. Izzo, J. Japelj, S.D. Vergani, Patricia Schady, A. Sagues Carracedo, A. de Ugarte Postigo, J.P. Anderson, C. Barbarino, J. Bolmer, A. Breeveld, P. Calissendorff, S. Campana, Z. Cano, R. Carini, S. Covino, P. D'Avanzo, V. D'Elia, M. della Valle, M. De Pasquale, J.P.U. Fynbo, M. Gromadzki, F. Hammer, D.H. Hartmann, K.E Heintz, C. Inserra, P. Jakobsson, D.A. Kann, J. Kotilainen, K. Maguire, N. Masetti, M. Nicholl, F.E. Olivares, G. Pugliese, A. Rossi, R. Salvaterra, J. Sollerman, M.B. Stone, G. Tagliaferri, L. Tomasella, C.C. Thoene, D. Xu, D.R. Young
Dec 31, 2019
Global population structure and evolution of Bordetella pertussis and their relationship with vaccination.
Marieke J Bart, Simon R Harris, Abdolreza Advani, Yoshichika Arakawa, Daniela Bottero, Valérie Bouchez, Pamela K Cassiday, Chuen-Sheue Chiang, Tine Dalby, Norman K Fry, María Emilia Gaillard, Marjolein van Gent, Nicole Guiso, Hans O Hallander, Eric T Harvill, Qiushui He, Han GJ van der Heide, Kees Heuvelman, Daniela F Hozbor, Kazunari Kamachi, Gennady I Karataev, Ruiting Lan, Anna Lutyńska, Ram P Maharjan, Jussi Mertsola, Tatsuo Miyamura, Sophie Octavia, Andrew Preston, Michael A Quail, Vitali Sintchenko, Paola Stefanelli, M Lucia Tondella, Raymond SW Tsang, Yinghua Xu, Shu-Man Yao, Shumin Zhang, Julian Parkhill, Frits R Mooi
Jun 25, 2019
Bordetella pertussis causes pertussis, a respiratory disease that is most severe for infants. Vaccination was introduced in the 1950s, and in recent years, a resurgence of disease was observed worldwide, with significant...
Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population
Alexia Cardona, Felix R Day, John RB Perry, Marie Loh, Audrey Y Chu, Benjamin Lehne, Dirk S Paul, Luca A Lotta, Isobel D Stewart, Nicola D Kerrison, Robert A Scott, Kay-Tee Khaw, Nita G Forouhi, Claudia Langenberg, Chunyu Liu, Michael M Mendelson, Daniel Levy, Stephan Beck, R David Leslie, Josée Dupuis, James B Meigs, Jaspal S Kooner, Jussi Pihlajamäki, Allan Vaag, Alexander Perfilyev, Charlotte Ling, Marie-France Hivert, John C Chambers, Nicholas J Wareham, Ken K Ong
Sep 20, 2019
Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However...
British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic.
Nicholas A Kennedy, Gareth-Rhys Jones, Christopher A Lamb, Richard Appleby, Ian Arnott, R Mark Beattie, Stuart Bloom, Alenka J Brooks, Rachel Cooney, Robin J Dart, Cathryn Edwards, Aileen Fraser, Daniel R Gaya, Subrata Ghosh, Kay Greveson, Richard Hansen, Ailsa Hart, A Barney Hawthorne, Bu'Hussain Hayee, Jimmy K Limdi, Charles D Murray, Gareth C Parkes, Miles Parkes, Kamal Patel, Richard C Pollok, Nick Powell, Chris S Probert, Tim Raine, Shaji Sebastian, Christian Selinger, Philip J Smith, Catherine Stansfield, Lisa Younge, James O Lindsay, Peter M Irving, Charlie W Lees
Jun 26, 2020
The COVID-19 pandemic is putting unprecedented pressures on healthcare systems globally. Early insights have been made possible by rapid sharing of data from China and Italy. In the UK, we have rapidly mobilised inflammatory...
Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes.
Kirstyn Brunker, Gurdeep Jaswant, S M Thumbi, Kennedy Lushasi, Ahmed Lugelo, Anna M Czupryna, Fred Ade, Gati Wambura, Veronicah Chuchu, Rachel Steenson, Chanasa Ngeleja, Criselda Bautista, Daria L Manalo, Ma Ricci R Gomez, Maria Yna Joyce V Chu, Mary Elizabeth Miranda, Maya Kamat, Kristyna Rysava, Jason Espineda, Eva Angelica V Silo, Ariane Mae Aringo, Rona P Bernales, Florencio F Adonay, Michael J Tildesley, Denise A Marston, Daisy L Jennings, Anthony R Fooks, Wenlong Zhu, Luke W Meredith, Sarah C Hill, Radoslaw Poplawski, Robert J Gifford, Joshua B Singer, Mathew Maturi, Athman Mwatondo, Roman Biek, Katie Hampson
Mar 26, 2020
Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic disease transmission and control in low- and middle-income countries. Rabies is an almost...
Rabies virus SURVEILLANCE phylogenetic Zoonoses nanopore Lyssavirus Neglected tropical diseases whole genome sequencing MinION Dog-mediated Rabies Field Sequencing
Published by: Wellcome open research
Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition.
SG Yammine, I Huybrechts, C Biessy, L Dossus, S Panico, MJ Sánchez, V Benetou, R Turzanski-Fortner, V Katzke, A Idahl, G Skeie, K Standahl Olsen, A Tjønneland, J Halkjær, S Colorado-Yohar, AK Heath, E Sonestedt, H Sartor, MB Schulze, D Palli, M Crous-Bou, A Dorronsoro, K Overvad, A Barricarte Gurrea, G Severi, RCH Vermeulen, TM Sandanger, RC Travis, T Key, P Amiano, B Van Guelpen, M Johansson, M Sund, R Tumino, N Wareham, C Sacerdote, V Krogh, P Brennan, E Riboli, E Weiderpass, MJ Gunter, V Chajès
Mar 19, 2023
Proceedings of the GRAPPA 2022 Executive Retreat
Beverly Cheok Kuan Ng, Deepak Jadon, Adewale Adebajo, Gizem Ayan, Kristina Callis Duffin, Vinod Chandran, Laura C Coates, Maria Antonietta D'Agostino, Kurt de Vlam, Atul Deodhar, Lihi Eder, Amit Garg, Dafna D Gladman, Niti Goel, Alice B Gottlieb, M Elaine Husni, Arnon Katz, Arthur Kavanaugh, Ennio Lubrano, Philip J Mease, Joseph F Merola, Peter Nash, Alexis Ogdie, Stephen R Pennington, Lourdes M Perez-Chada, Fabian Proft, Cheryl F Rosen, Laura Savage, Claudia Goldenstein-Schainberg, Stefan Siebert, Enrique R Soriano, Ingrid Steinkoenig, William Tillett, April W Armstrong, Oliver FitzGerald
Nov 01, 2023
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) leadership congregated for a strategic planning meeting before the 2022 GRAPPA annual meeting in New York, USA. Meeting aims were to review...
Solving the conundrum of intra-specific variation in metabolic rate: A multidisciplinary conceptual and methodological toolkit: New technical developments are opening the door to an understanding of why metabolic rate varies among individual animals of a species
Neil B Metcalfe, Jakob Bellman, Pierre Bize, Pierre U Blier, Amélie Crespel, Neal J Dawson, Ruth E Dunn, Lewis G Halsey, Wendy R Hood, Mark Hopkins, Shaun S Killen, Darryl McLennan, Lauren E Nadler, Julie JH Nati, Matthew J Noakes, Tommy Norin, Susan E Ozanne, Malcolm Peaker, Amanda K Pettersen, Anna Przybylska-Piech, Alann Rathery, Charlotte Récapet, Enrique Rodríguez, Karine Salin, Antoine Stier, Elisa Thoral, Klaas R Westerterp, Margriet S Westerterp-Plantenga, Michał S Wojciechowski, Pat Monaghan
Apr 12, 2023
Researchers from diverse disciplines, including organismal and cellular physiology, sports science, human nutrition, evolution and ecology, have sought to understand the causes and consequences of the surprising variation in...
Spectrum, risk factors and outcomes of neurological and psychiatric complications of COVID-19
Amy L Ross Russell, Marc Hardwick, Athavan Jeyanantham, Laura M White, Saumitro Deb, Girvan Burnside, Harriet M Joy, Craig J Smith, Thomas A Pollak, Timothy R Nicholson, Nicholas WS Davies, Hadi Manji, Ava Easton, Stephen Ray, Michael S Zandi, Jonathan P Coles, David K Menon, Aravinthan Varatharaj, Beth McCausland, Mark A Ellul, Naomi Thomas, Gerome Breen, Stephen Keddie, Michael P Lunn, John PS Burn, Graziella Quattrocchi, Luke Dixon, Claire M Rice, George Pengas, Rustam Al-Shahi Salman, Alan Carson, Eileen M Joyce, Martin R Turner, Laura A Benjamin, Tom Solomon, Rachel Kneen, Sarah Pett, Rhys H Thomas, Benedict D Michael, Ian Galea
Jun 16, 2021
SARS-CoV-2 is associated with new-onset neurological and psychiatric conditions. Detailed clinical data, including factors associated with recovery, are lacking, hampering prediction modelling and targeted therapeutic...
Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome
Eric Legius, Ludwine Messiaen, Pierre Wolkenstein, Patrice Pancza, Robert A Avery, Yemima Berman, Jaishri Blakeley, Dusica Babovic-Vuksanovic, Karin Soares Cunha, Rosalie Ferner, Michael J Fisher, Jan M Friedman, David H Gutmann, Hildegard Kehrer-Sawatzki, Bruce R Korf, Victor-Felix Mautner, Sirkku Peltonen, Katherine A Rauen, Vincent Riccardi, Elizabeth Schorry, Anat Stemmer-Rachamimov, David A Stevenson, Gianluca Tadini, Nicole J Ullrich, David Viskochil, Katharina Wimmer, Kaleb Yohay, International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), Susan M Huson, D Gareth Evans, Scott R Plotkin
Aug 11, 2021
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Juan D Matute, Jinzhi Duan, Magdalena B Flak, Paul Griebel, Jose A Tascon-Arcila, Shauni Doms, Thomas Hanley, Agne Antanaviciute, Jennifer Gundrum, Jessica L Mark Welch, Brandon Sit, Shabnam Abtahi, Gwenny M Fuhler, Joep Grootjans, Florian Tran, Stephanie T Stengel, James R White, Niklas Krupka, Dirk Haller, Simon Clare, Trevor D Lawley, Arthur Kaser, Alison Simmons, Jonathan N Glickman, Lynn Bry, Philip Rosenstiel, Gary Borisy, Matthew K Waldor, John F Baines, Jerrold R Turner, Richard S Blumberg
Dec 23, 2022
Published by: J Exp Med
Polymeric nanobiotics as a novel treatment for mycobacterial infections.
Iris L Batalha, Audrey Bernut, Mark Schiebler, Myriam M Ouberai, Charlotte Passemar, Catherine Klapholz, Sonja Kinna, Sarah Michel, Kasim Sader, Pablo Castro-Hartmann, Stephen A Renshaw, Mark E Welland, R Andres Floto
Oct 28, 2019
antibiotic clofazimine Isoniazid Mycobacterium tuberculosis Nanoparticles Polymer-drug conjugate Zebrafish Animals Antitubercular Agents clofazimine Delayed-Action Preparations Disease Models Animal Drug Combinations Drug Delivery Systems Humans Isoniazid MACROPHAGES Mycobacterium tuberculosis Nanoparticles Polymers Tuberculosis Zebrafish
Transcutaneous vagus nerve stimulation (t-VNS)
Katherine E Manning, Jessica A Beresford-Webb, Lucie C S Aman, Howard A Ring, Peter C Watson, Stephen W Porges, Chris Oliver, Sally R Jennings, Anthony J Holland
Jan 06, 2020
Temper outbursts are a severe problem for people with Prader-Willi Syndrome (PWS). Previous reports indicate that vagus nerve stimulation (VNS) may reduce maladaptive behaviour in neurodevelopmental disorders, including PWS. We...
Novel Approach to Imaging Active Takayasu Arteritis Using Somatostatin Receptor Positron Emission Tomography/Magnetic Resonance Imaging.
Jason M Tarkin, Christopher Wall, Deepa Gopalan, Luigi Aloj, Roido Manavaki, Tim D Fryer, Eric O Aboagye, Martin R Bennett, James E Peters, James HF Rudd, Justin C Mason
Jan 08, 2020
Takayasu arteritis Aortic Diseases Molecular Imaging positron emission tomography Vasculitis Adult Aorta Biomarkers Female Fluorodeoxyglucose F18 Glucocorticoids Humans Immunosuppressive Agents Magnetic Resonance Imaging Middle Aged Molecular Imaging Organometallic Compounds Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Receptors Somatostatin Takotsubo cardiomyopathy Treatment Outcome
Comparative Cell Surface Proteomic Analysis of the Primary Human T Cell and Monocyte Responses to Type I Interferon.
Lior Soday, Martin Potts, Leah M Hunter, Benjamin J Ravenhill, Jack W Houghton, James C Williamson, Robin Antrobus, Mark R Wills, Nicholas J Matheson, Michael P Weekes
Feb 24, 2021
The cellular response to interferon (IFN) is essential for antiviral immunity, IFN-based therapy and IFN-related disease. The plasma membrane (PM) provides a critical interface between the cell and its environment, and is the...
The potential shared role of inflammation in insulin resistance and schizophrenia
Benjamin I. Perry, Stephen Burgess, Hannah J. Jones, Stan Zammit, Rachel Upthegrove, Amy M. Mason, Felix R. Day, Claudia Langenberg, Nicholas J. Wareham, Peter B. Jones, Golam M. Khandaker
Mar 12, 2021
Background: Insulin resistance predisposes to cardiometabolic disorders, which are commonly comorbid with schizophrenia and are key contributors to the significant excess mortality in schizophrenia. Mechanisms for the...
Catalyst-Mediated Enhancement of Carbon Nanotube Textiles by Laser Irradiation
Thurid S. Gspann, Adarsh Kaniyoor, Wei Tan, Philipp A. Kloza, John S. Bulmer, Jennifer Mizen, Giorgio Divitini, Jeronimo Terrones, Daniel Tune, John D. Cook, Fiona R. Smail, James A. Elliott
Mar 12, 2021
The photonic post-processing of suspended carbon nanotube (CNT) ribbons made by floating catalyst chemical vapor deposition (FC-CVD) results in selective sorting of the carbon nanotubes present. Defective, thermally...
Phenotypic and functional characterization of first-trimester human placental macrophages, Hofbauer cells.
Orvinols with mixed kappa/mu opioid receptor agonist activity
Ben M Greedy, F Bradbury, Mark P Thomas, K Grivas, Gerta Cami-Kobeci, Ashley Archambeau, Kelly Bosse, Mary J Clark, Mario Aceto, John W Lewis, John R Traynor, Stephen M Husbands
Jan 01, 0001
Dual-acting kappa opioid receptor (KOR) agonist and mu opioid receptor (MOR) partial agonist ligands have been put forward as potential treatment agents for cocaine and other psychostimulant abuse. Members of the orvinol...
The Grizzly, September 22, 2011
Liz Kilmer, Nick Pane, Jordan Demcher, Rosie Clark, Lisa Jobe, Michael Schmidt, Jenna Yaich, Sarah Bollert, James Noebels, Annabel Clarance, Connor Gregory, Sara Mohler, Sabrina McGettigan, Christiana Gross, R. Erich Bassler, Marina McCann, Victoria Cameron
Jan 01, 0001
Hundreds Gather for Family Day Fefu Offers Questions, not Answers Phonathon Raising the Bar Internship Profile: The Hill School New Psychology Professor Looks to Promote Research Woman to Watch: Kelly Reynolds Campus...
Ursinus College Collegeville Pennsylvania newspaper Family Day theater fundraising Jennifer Stevenson The Hill School Kelly Reynolds cyber-bullying alcohol policy Skin We're In Volleyball Diana Clavin Homecoming Patterson Field field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration.
Jana Koth, Xiaonan Wang, Abigail C Killen, William T Stockdale, Helen G Potts, Andrew Jefferson, Florian Bonkhofer, Paul R Riley, Roger K Patient, Berthold Göttgens, Mathilda TM Mommersteeg
Mar 06, 2020
Heart Regeneration RUNX1 scRNA-seq Zebrafish Animals Annexin A2 Cell Proliferation Cicatrix Core Binding Factor Alpha 2 Subunit endocardium Gene Expression Regulation Developmental Heart Muscle Smooth Mutation Myocardium Myofibroblasts Myosin Heavy Chains Regeneration Up-Regulation Zebrafish Zebrafish Proteins
Type I interferon induces CXCL13 to support ectopic germinal center formation.
Alice E Denton, Silvia Innocentin, Edward J Carr, Barry M Bradford, Fanny Lafouresse, Neil A Mabbott, Urs Mörbe, Burkhard Ludewig, Joanna R Groom, Kim L Good-Jacobson, Michelle A Linterman
Sep 18, 2019
Ectopic lymphoid structures form in a wide range of inflammatory conditions, including infection, autoimmune disease, and cancer. In the context of infection, this response can be beneficial for the host: influenza A virus...
Intergenerational transmission of child maltreatment using a multi-informant multi-generation family design.
Renate SM Buisman, Katharina Pittner, Marieke S Tollenaar, Jolanda Lindenberg, Lisa JM van den Berg, Laura HCG Compier-De Block, Joost R van Ginkel, Lenneke RA Alink, Marian J Bakermans-Kranenburg, Bernet M Elzinga, Marinus H van IJzendoorn
Apr 12, 2020
In the current study a three-generational design was used to investigate intergenerational transmission of child maltreatment (ITCM) using multiple sources of information on child maltreatment: mothers, fathers and children. A...
Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner.
Liling Shan, Shuang Li, Jan Meeldijk, Bernadet Blijenberg, Astrid Hendriks, Karlijn J W M van Boxtel, Sara P H van den Berg, Ian J Groves, Martin Potts, Adriana Svrlanska, Thomas Stamminger, Mark R Wills, Niels Bovenschen
May 16, 2020
Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8+ T cells and NK cells) control HCMV infection by...
Published by: PLoS pathogens
Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes
Lalantha Leelarathna, Sibylle Dellweg, Julia K Mader, Katharine Barnard, Carsten Benesch, Martin Ellmerer, Lutz Heinemann, Harald Kojzar, Hood Thabit, Malgorzata E Wilinska, Tim Wysocki, Thomas R Pieber, Sabine Arnolds, Mark L Evans, Roman Hovorka, AP@home Consortium
Feb 14, 2020
INTRODUCTION: Despite therapeutic advances, many people with type 1 diabetes are still unable to achieve optimal glycaemic control, limited by the occurrence of hypoglycaemia. The objective of the present study is to determine...
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