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Results: 860
A Double-blind, Randomized, Placebo-controlled Trial of Lactobacillus acidophilus for the Treatment of Acute Watery Diarrhea in Vietnamese Children.
Tran Thi Hong Chau, Nguyen Ngoc Minh Chau, Nhat Thanh Hoang Le, Hao Chung The, Phat Voong Vinh, Nguyen Thi Nguyen To, Nguyen Minh Ngoc, Ha Manh Tuan, Tang Le Chau Ngoc, Marion-Eliette Kolader, Jeremy J Farrar, Marcel Wolbers, Guy E Thwaites, Stephen Baker, Oxford-Vietnam Probiotics Study Group
Aug 02, 2019
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Nov 28, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis.
Nguyen TT Thuong, Dorothee Heemskerk, Trinh TB Tram, Le TP Thao, Lalita Ramakrishnan, Vu TN Ha, Nguyen D Bang, Tran TH Chau, Nguyen H Lan, Maxine Caws, Sarah J Dunstan, Nguyen VV Chau, Marcel Wolbers, Nguyen TH Mai, Guy E Thwaites
Nov 21, 2018
BACKGROUND: Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that the genotype of leukotriene A4 hydrolase (encoded by LTA4H), which...
Leukotriene A4 hydrolase genotype Cytokines inflammatory response survival. Tuberculous meningitis Adolescent Adult Aged Aged 80 and over Antiretroviral Therapy Highly Active Antitubercular Agents Cerebrum Cytokines Epoxide Hydrolases Female Genotype HIV Infections Humans Inflammation Kaplan-Meier Estimate Leukocytes Male Middle Aged Multivariate Analysis Mycobacterium tuberculosis Polymorphism Single Nucleotide Proportional Hazards Models Survival Analysis Tuberculosis Meningeal Young Adult
Invasive Non-typhoidal Salmonella Infections in Asia
Nguyen Phu Huong Lan, Tu Le Thi Phuong, Hien Nguyen Huu, Le Thuy, Alison E Mather, Se Eun Park, Florian Marks, Guy E Thwaites, Nguyen Van Vinh Chau, Corinne N Thompson, Stephen Baker
Feb 19, 2019
Invasive non-typhoidal Salmonella (iNTS) infections are now a well-described cause of morbidity and mortality in children and HIV-infected adults in sub-Saharan Africa. In contrast, the epidemiology and clinical manifestations...
Adult Aged Anti-Infective Agents Ceftriaxone Drug Therapy Combination Female Fluoroquinolones HIV Infections Hospitals Humans Logistic Models Male Middle Aged Multilocus Sequence Typing Multivariate Analysis Retrospective Studies Salmonella Infections Salmonella enterica Serogroup Sex Factors Trimethoprim Sulfamethoxazole Drug Combination Typhoid Fever Vietnam
Viral Metagenomic Analysis of Cerebrospinal Fluid from Patients with Acute Central Nervous System Infections of Unknown Origin, Vietnam.
Nguyen To Anh, Le Nguyen Truc Nhu, Nguyen Thi Thu Hong, Tran My Phuc, Pham Thi Thanh Tam, Dang Thao Huong, Tran Tuan Anh, Xutao Deng, Ho Dang Trung Nghia, Tran Thua Nguyen, Nguyen Van Hung, Nguyen Dac Thuan, Pham Thi Hong Phuong, Nguyen Van Vinh Chau, Stephen Baker, Eric Delwart, Guy Thwaites, Le Van Tan, VIZIONS Consortium1
May 17, 2021
Central nervous system (CNS) infection is a serious neurologic condition, although the etiology remains unknown in >50% of patients. We used metagenomic next-generation sequencing to detect viruses in 204 cerebrospinal fluid...
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Jul 28, 2021
Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients.
Hoang NH Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E Thwaites, Lindsay J Hall, Daniel J Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The
Oct 29, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker. Despite its significance in the promotion of...
The Control of Typhoid Fever in Vietnam.
Tran Vu Thieu Nga, Pham Thanh Duy, Nguyen Phu Huong Lan, Nguyen Van Vinh Chau, Stephen Baker
Apr 10, 2019
Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), is a diminishing public health problem in Vietnam, and this process may represent a prototype for typhoid elimination in Asia. Here, we review typhoid...
An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao People´s Democratic Republic.
Lisa Hefele, Antony P Black, Trinh Van Tan, Nguyen Tri Minh, Nguyen Duc Hoang, Siriphone Virachith, Claude P Muller, Judith M Hübschen, Paula Russell, Josefin Bartholdson Scott, Chau Nguyen Ngoc Minh, Tran Vu Thieu Nga, Stephen Baker
Jan 28, 2022
The epidemiology of typhoid fever in Lao People`s Democratic Republic is poorly defined. Estimating the burden of typhoid fever in endemic countries is complex due to the cost and limitations of population-based surveillance;...
A universal genome sequencing method for rotavirus A from human fecal samples which identifies segment reassortment and multi-genotype mixed infection.
Tran Thi Ngoc Dung, Pham Thanh Duy, October M Sessions, Uma K Sangumathi, Voong Vinh Phat, Pham Thi Thanh Tam, Nguyen Thi Nguyen To, Tran My Phuc, Tran Thi Hong Chau, Nguyen Ngoc Minh Chau, Ngoc Nguyen Minh, Guy E Thwaites, Maia A Rabaa, Stephen Baker
Apr 10, 2019
BACKGROUND: Genomic characterization of rotavirus (RoV) has not been adopted at large-scale due to the complexity of obtaining sequences for all 11 segments, particularly when feces are used as starting material. METHODS: To...
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh.
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Oct 04, 2021
BACKGROUND: Hepatitis E virus (HEV) infection is endemic in Bangladesh and there are occasional outbreaks. The molecular characteristics and pathogenesis of endemic and outbreak HEV strains are poorly understood. We compared the...
A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh.
Trang Nguyen Hoa, Saif Ullah Munshi, Khanh Nguyen Ngoc, Chau Le Ngoc, Thanh Tran Thi Thanh, Tahmina Akther, Shahina Tabassum, Nilufa Parvin, Stephen Baker, Motiur Rahman
Aug 26, 2021
Background
Hepatitis E virus (HEV) infection is endemic in Bangladesh and there are occasional outbreaks. The molecular characteristics and pathogenesis of endemic and outbreak HEV strains are poorly understood. We...
Published by: PLOS ONE
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
Chau Le Ngoc, Thanh Tran Thi Thanh, Phuong Tran Thi Lan, Trinh Nguyen Mai, Trang Nguyen Hoa, Ngoc Nghiem My, Tan Le Van, Hung Le Manh, Phuong Le Thanh, Chau Nguyen Van Vinh, Guy Thwaites, Graham Cooke, Gabrielle M Heilek, Cecilia Shikuma, Thuy Le, Stephen Baker, Motiur Rahman, VIZIONS consortium
Apr 10, 2019
BACKGROUND: The highest burden of disease from hepatitis C virus (HCV) is found in Southeast Asia, but our understanding of the epidemiology of infection in many heavily burdened countries is still limited. In particular, there...
An age-stratified serosurvey against purified Salmonella enterica serovar Typhi antigens in the Lao People´s Democratic Republic.
Lisa Hefele, Antony P Black, Trinh Van Tan, Nguyen Tri Minh, Nguyen Duc Hoang, Siriphone Virachith, Claude P Muller, Judith M Hübschen, Paula Russell, Josefin Bartholdson Scott, Chau Nguyen Ngoc Minh, Tran Vu Thieu Nga, Stephen Baker
Jan 05, 2022
The epidemiology of typhoid fever in Lao People`s Democratic Republic is poorly defined. Estimating the burden of typhoid fever in endemic countries is complex due to the cost and limitations of population-based surveillance;...
Prognostic models for 9 month mortality in tuberculous meningitis
Le Thi Phuong Thao, A Dorothee Heemskerk, Ronald B Geskus, Nguyen Thi Hoang Mai, Dang Thi Minh Ha, Tran Thi Hong Chau, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Maxine Caws, Nguyen Huu Lan, Do Dang Anh Thu, Nguyen Thuy Thuong Thuong, Jeremy Day, Jeremy J Farrar, M Estee Torok, Nguyen Duc Bang, Guy E Thwaites, Marcel Wolbers
May 02, 2018
Dynamic Prediction of Death in Patients With Tuberculous Meningitis Using Time-updated Glasgow Coma Scale and Plasma Sodium Measurements.
Le Thi Phuong Thao, Marcel Wolbers, A Dorothee Heemskerk, Nguyen Thi Hoang Mai, Dang Thi Minh Ha, Tran Thi Hong Chau, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Maxine Caws, Nguyen Huu Lan, Do Dang Anh Thu, Nguyen Thuy Thuong Thuong, Jeremy Day, M Estee Torok, Nguyen Duc Bang, Guy E Thwaites, Ronald B Geskus
Apr 16, 2019
Pathogenic Escherichia coli Possess Elevated Growth Rates under Exposure to Sub-Inhibitory Concentrations of Azithromycin
Tran Tuan-Anh, Ha Thanh Tuyen, Nguyen Ngoc Minh Chau, Nguyen Duc Toan, Tran Hanh Triet, Le Minh Triet, Nguyen Hoang Thu Trang, Nguyen Thi Nguyen To, Josefin Bartholdson Scott, Hao Chung The, Duy Pham Thanh, Hannah Clapham, Stephen Baker
Oct 29, 2020
Antimicrobial resistance (AMR) has been identified by the World Health Organization (WHO) as one of the ten major threats to global health. Advances in technology, including whole-genome sequencing, have provided new insights...
Dexamethasone and long-term outcome of tuberculous meningitis in Vietnamese adults and adolescents.
M Estée Török, Duc Bang Nguyen, Thi Hong Chau Tran, Thi Bich Yen Nguyen, Guy E Thwaites, Thi Quy Hoang, Huy Dung Nguyen, Tinh Hien Tran, Tran Chinh Nguyen, Hoang Thi Thanh Hoang, Marcel Wolbers, Jeremy J Farrar
Jun 26, 2018
BACKGROUND: Dexamethasone has been shown to reduce mortality in patients with tuberculous meningitis but the long-term outcome of the disease is unknown. METHODS: Vietnamese adults and adolescents with tuberculous meningitis...
Pathogenic Escherichia coli Possess Elevated Growth Rates under Exposure to Sub-Inhibitory Concentrations of Azithromycin.
Tran Tuan-Anh, Ha Thanh Tuyen, Nguyen Ngoc Minh Chau, Nguyen Duc Toan, Tran Hanh Triet, Le Minh Triet, Nguyen Hoang Thu Trang, Nguyen Thi Nguyen To, Josefin Bartholdson Scott, Hao Chung The, Duy Pham Thanh, Hannah Clapham, Stephen Baker
Dec 07, 2020
Antimicrobial resistance (AMR) has been identified by the World Health Organization (WHO) as one of the ten major threats to global health. Advances in technology, including whole-genome sequencing, have provided new insights...
Hospital-acquired colonization and infections in a Vietnamese intensive care unit.
Duong Bich Thuy, James Campbell, Le Thanh Hoang Nhat, Nguyen Van Minh Hoang, Nguyen Van Hao, Stephen Baker, Ronald B Geskus, Guy E Thwaites, Nguyen Van Vinh Chau, C Louise Thwaites
Apr 10, 2019
Data concerning intensive care unit (ICU)-acquired bacterial colonization and infections are scarce from low and middle-income countries (LMICs). ICU patients in these settings are at high risk of becoming colonized and infected...
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia.
Kelly L Wyres, To NT Nguyen, Margaret MC Lam, Louise M Judd, Nguyen Van Vinh Chau, David AB Dance, Margaret Ip, Abhilasha Karkey, Clare L Ling, Thyl Miliya, Paul N Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R Thomson, Stephen Baker, Kathryn E Holt
Mar 02, 2020
BACKGROUND: Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment...
Aetiology and Potential Animal Exposure in Central Nervous System Infections in Vietnam.
Hannah E Brindle, Behzad Nadjm, Marc Choisy, Rob Christley, Michael Griffiths, Stephen Baker, Juliet E Bryant, James I Campbell, Van Vinh Chau Nguyen, Thi Ngoc Diep Nguyen, Ty Thi Hang Vu, Van Hung Nguyen, Bao Long Hoang, Xuan Luat Le, Ha My Pham, Thi Dieu Ngan Ta, Dang Trung Nghia Ho, Thua Nguyen Tran, Thi Han Ny Nguyen, My Phuc Tran, Thi Hong Phuong Pham, Van Tan Le, Dac Thuan Nguyen, Thi Thu Trang Hau, Ngoc Vinh Nguyen, Heiman FL Wertheim, Guy E Thwaites, H Rogier van Doorn, VIZIONS consortium
Nov 16, 2022
An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal...
Large-Scale Software-Defined IoT Platform for Provisioning IoT Services on Demand
Internet of things (IoT) has developed into an interconnected platform infrastructure for providing everyday services. Emerging end-to-end IoT services are being developed for local and multiple distributed regions. To realize...
Published by: IGI Global Scientific Publishing
Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia.
Kelly L Wyres, To N T Nguyen, Margaret M C Lam, Louise M Judd, Nguyen Van Vinh Chau, David A B Dance, Margaret Ip, Abhilasha Karkey, Clare L Ling, Thyl Miliya, Paul N Newton, Nguyen Phu Huong Lan, Amphone Sengduangphachanh, Paul Turner, Balaji Veeraraghavan, Phat Voong Vinh, Manivanh Vongsouvath, Nicholas R Thomson, Stephen Baker, Kathryn E Holt
Feb 19, 2020
BACKGROUND:Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment...
Published by: Genome medicine
Aetiology and Potential Animal Exposure in Central Nervous System Infections in Vietnam.
Hannah E Brindle, Behzad Nadjm, Marc Choisy, Rob Christley, Michael Griffiths, Stephen Baker, Juliet E Bryant, James I Campbell, Van Vinh Chau Nguyen, Thi Ngoc Diep Nguyen, Ty Thi Hang Vu, Van Hung Nguyen, Bao Long Hoang, Xuan Luat Le, Ha My Pham, Thi Dieu Ngan Ta, Dang Trung Nghia Ho, Thua Nguyen Tran, Thi Han Ny Nguyen, My Phuc Tran, Thi Hong Phuong Pham, Van Tan Le, Dac Thuan Nguyen, Thi Thu Trang Hau, Ngoc Vinh Nguyen, Heiman FL Wertheim, Guy E Thwaites, H Rogier van Doorn, VIZIONS consortium
Feb 03, 2023
An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal...
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