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Dynamic interventions to control COVID-19 pandemic
Rajiv Chowdhury, Kevin Heng, Md Shajedur Rahman Shawon, Gabriel Goh, Daisy Okonofua, Carolina Ochoa-Rosales, Valentina Gonzalez-Jaramillo, Abbas Bhuiya, Daniel Reidpath, Shamini Prathapan, Sara Shahzad, Christian L Althaus, Nathalia Gonzalez-Jaramillo, Oscar H Franco, Global Dynamic Interventions Strategies for COVID-19 Collaborative Group
Aug 07, 2020
To date, non-pharmacological interventions (NPI) have been the mainstay for controlling the coronavirus disease-2019 (COVID-19) pandemic. While NPIs are effective in preventing health systems overload, these long-term measures...
Written Reminiscences of Dorothea Jansen
These written responses were completed by Dorothea Jansen as part of Project 2020: A Collaborative Oral History. These recollections provide insight into the COVID-19 pandemic and critical year 2020, notably from the perspective...
Published by: Winthrop University
How COVID-19 changed clinical research strategies
Annina Bauer, Anja Eskat, Atara Ntekim, Creany Wong, Deborah Eberle, Elham Hedayati, Fabian Tay, Henry Yau, Louise Stockley, María de Medina Redondo, Selçuk Şen, Silvia Egert-Schwender, Yağız Üresin, Regina Grossmann
May 28, 2022
OBJECTIVE: Clinical research has faced new challenges during the COVID-19 pandemic, leading to excessive operational demands affecting all stakeholders. We evaluated the impact of COVID-19 on clinical research strategies and...
How COVID-19 changed clinical research strategies
Annina Bauer, Anja Eskat, Atara Ntekim, Creany Wong, Deborah Eberle, Elham Hedayati, Fabian Tay, Henry Yau, Louise Stockley, María de Medina Redondo, Selçuk Şen, Silvia Egert-Schwender, Yağız Üresin, Regina Grossmann
Apr 28, 2022
OBJECTIVE: Clinical research has faced new challenges during the COVID-19 pandemic, leading to excessive operational demands affecting all stakeholders. We evaluated the impact of COVID-19 on clinical research strategies and...
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative
Jan 05, 2022
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of...
Autoimmunity Body Mass Index covid-19 Critical Illness Female Genetic Loci Genetic Predisposition to Disease Genome-Wide Association Study Geographic Mapping Hospitalization Host-Pathogen Interactions Humans Inflammation Information Dissemination Male Multifactorial Inheritance Racial Groups SARS-CoV-2 Smoking
Dynamic interventions to control COVID-19 pandemic
Rajiv Chowdhury, Kevin Heng, Md Shajedur Rahman Shawon, Gabriel Goh, Daisy Okonofua, Carolina Ochoa-Rosales, Valentina Gonzalez-Jaramillo, Abbas Bhuiya, Daniel Reidpath, Shamini Prathapan, Sara Shahzad, Christian L. Althaus, Nathalia Gonzalez-Jaramillo, Oscar H. Franco
May 20, 2021
Abstract: To date, non-pharmacological interventions (NPI) have been the mainstay for controlling the coronavirus disease-2019 (COVID-19) pandemic. While NPIs are effective in preventing health systems overload, these long-term...
Dynamic interventions to control COVID-19 pandemic
Rajiv Chowdhury, Kevin Heng, Md Shajedur Rahman Shawon, Gabriel Goh, Daisy Okonofua, Carolina Ochoa-Rosales, Valentina Gonzalez-Jaramillo, Abbas Bhuiya, Daniel Reidpath, Shamini Prathapan, Sara Shahzad, Christian L. Althaus, Nathalia Gonzalez-Jaramillo, Oscar H. Franco
Jun 06, 2020
Abstract: To date, non-pharmacological interventions (NPI) have been the mainstay for controlling the coronavirus disease-2019 (COVID-19) pandemic. While NPIs are effective in preventing health systems overload, these long-term...
The effect of human mobility and control measures on the COVID-19 epidemic in China.
Moritz UG Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R Faria, Ruoran Li, William P Hanage, John S Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G Pybus, Samuel V Scarpino
May 26, 2020
The ongoing coronavirus disease 2019 (COVID-19) outbreak expanded rapidly throughout China. Major behavioral, clinical, and state interventions were undertaken to mitigate the epidemic and prevent the persistence of the virus in...
Elective surgery cancellations due to the COVID-19 pandemic
COVIDSurg Collaborative
May 15, 2020
BACKGROUND: The COVID-19 pandemic has disrupted routine hospital services globally. This study estimated the total number of adult elective operations that would be cancelled worldwide during the 12 weeks of peak disruption due...
Reminiscences of Biology 213-214
This collection of written reminiscences includes seven written accounts relating to the COVID-19 pandemic and 2020 experience, notably from the student perspective. Seven college students from a Winthrop Biology course...
Published by: Winthrop University
Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients
Barbara Mühlemann, Charlotte Thibeault, David Hillus, Elisa T Helbig, Lena J Lippert, Pinkus Tober-Lau, Tatjana Schwarz, Marcel A Müller, Pa-COVID-19 collaborative study group, Martin Witzenrath, Norbert Suttorp, Leif E Sander, Christian Drosten, Terry C Jones, Victor M Corman, Florian Kurth
Jul 28, 2021
OBJECTIVES: Dexamethasone has become the standard of care for severe coronavirus disease 2019 (COVID-19), but its virological impact is poorly understood. The objectives of this work were to characterize the kinetics of severe...
Antibody COVID-19 Nucleic Acid Testing Coronavirus disease 2019 (COVID-19) Dexamethasone Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Viral concentration Anti-Inflammatory Agents Antibodies Viral covid-19 Dexamethasone Hospitalization Humans Immunoglobulin A Immunoglobulin G Kinetics Prospective Studies RNA Viral Respiratory System SARS-CoV-2 Seroconversion Viral Load COVID-19 Drug Treatment
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England.
Quentin J Leclerc, Naomi M Fuller, Ruth H Keogh, Karla Diaz-Ordaz, Richard Sekula, Malcolm G Semple, ISARIC4C investigators, CMMID COVID-19 working group, Katherine E Atkins, Simon R Procter, Gwenan M Knight
Aug 02, 2021
BACKGROUND: Predicting bed occupancy for hospitalised patients with COVID-19 requires understanding of length of stay (LoS) in particular bed types. LoS can vary depending on the patient's "bed pathway" - the sequence of...
Awareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic
Nguyen Tien Huy, R Matthew Chico, Vuong Thanh Huan, Hosam Waleed Shaikhkhalil, Vuong Ngoc Thao Uyen, Ahmad Taysir Atieh Qarawi, Shamael Thabit Mohammed Alhady, Nguyen Lam Vuong, Le Van Truong, Mai Ngoc Luu, Shyam Prakash Dumre, Atsuko Imoto, Peter N Lee, Dao Ngoc Hien Tam, Sze Jia Ng, Mohammad Rashidul Hashan, Mitsuaki Matsui, Nguyen Tran Minh Duc, Sedighe Karimzadeh, Nut Koonrungsesomboon, Chris Smith, Sharon Cox, Kazuhiko Moji, Kenji Hirayama, Le Khac Linh, Kirellos Said Abbas, Tran Nu Thuy Dung, Tareq Mohammed Ali Al-Ahdal, Emmanuel Oluwadare Balogun, Nguyen The Duy, Mennatullah Mohamed Eltaras, Trang Huynh, Nguyen Thi Linh Hue, Bui Diem Khue, Abdelrahman Gad, Gehad Mohamed Tawfik, Kazumi Kubota, Hoang-Minh Nguyen, Dmytro Pavlenko, Vu Thi Thu Trang, Le Thuong Vu, Tran Hai Yen, Nguyen Thi Yen-Xuan, Luong Thi Trang, Vinh Dong, Akash Sharma, Vu Quoc Dat, Mohammed Soliman, Jeza Abdul Aziz, Jaffer Shah, Pham Dinh Long Hung, Yap Siang Jee, Dang Thuy Ha Phuong, Tran Thuy Huong Quynh, Hoang Thi Nam Giang, Vy Thi Nhat Huynh, Nguyen Anh Thi, Nacir Dhouibi, Truc Phan, Vincent Duru, Nguyen Hai Nam, Sherief Ghozy, contributors of the TMGH-Global COVID-19 Collaborative, TMGH-Global COVID-19 Collaborative
Jan 28, 2022
BACKGROUND: Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time...
Impact of COVID-19 pandemic on surgical neuro-oncology multi-disciplinary team decision making
Stephen John Price, Alexis Joannides, Puneet Plaha, Fardad Taghizadeh Afshari, Erminia Albanese, Neil U Barua, Huan Wee Chan, Giles Critchley, Thomas Flannery, Daniel M Fountain, Ryan K Mathew, Rory J Piper, Michael TC Poon, Chittoor Rajaraman, Ola Rominiyi, Stuart Smith, Georgios Solomou, Anna Solth, Surash Surash, Victoria Wykes, Colin Watts, Helen Bulbeck, Peter Hutchinson, Michael D Jenkinson, COVID-CNSMDT study group
Aug 17, 2020
OBJECTIVES: Pressures on healthcare systems due to COVID-19 has impacted patients without COVID-19 with surgery disproportionally affected. This study aims to understand the impact on the initial management of patients with...
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, Giuseppe Citerio, Andy Conway Morris, Gennaro De Pascale, Frantisek Duska, Paul Elbers, Sharon Einav, Lui Forni, Laura Galarza, Armand RJ Girbes, Giacomo Grasselli, Vitaly Gusarov, Alasdair Jubb, Jozef Kesecioglu, Andrea Lavinio, Maria Cruz Martin Delgado, Johannes Mellinghoff, Sheila Nainan Myatra, Marlies Ostermann, Mariangela Pellegrini, Pedro Povoa, Stefan J Schaller, Jean-Louis Teboul, Adrian Wong, Jan J De Waele, Maurizio Cecconi, ESICM UNITE-COVID investigators
Jul 07, 2022
PURPOSE: To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously...
Interview with Deitre Owens Helvy
This interview was conducted by Winthrop student Michaela Bessinger with Deitre Owens Helvy as part of Project 2020: A Collaborative Oral History. Helvy details her experiences as a Black female educator in Greenville County...
Covid-19 pandemic 2020 Education Virtual learning Greenville County School District social justice race
Published by: Winthrop University
Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY)
RECOVERY Collaborative Group
May 25, 2021
BACKGROUND: In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. METHODS: This randomised, controlled, open-label...
Clinical and organizational factors associated with mortality during the peak of first COVID-19 wave
Massimiliano Greco, Thomas De Corte, Ari Ercole, Massimo Antonelli, Elie Azoulay, Giuseppe Citerio, Andy Conway Morris, Gennaro De Pascale, Frantisek Duska, Paul Elbers, Sharon Einav, Lui Forni, Laura Galarza, Armand RJ Girbes, Giacomo Grasselli, Vitaly Gusarov, Alasdair Jubb, Jozef Kesecioglu, Andrea Lavinio, Maria Cruz Martin Delgado, Johannes Mellinghoff, Sheila Nainan Myatra, Marlies Ostermann, Mariangela Pellegrini, Pedro Povoa, Stefan J Schaller, Jean-Louis Teboul, Adrian Wong, Jan J De Waele, Maurizio Cecconi, ESICM UNITE-COVID investigators
Jun 17, 2022
PURPOSE: To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously...
Pricing Strategies of Multinationals for Global Markets – Considerations and Initiatives
Pratap Mandal
Jan 01, 2020
Multinationals require analyzing a number of pricing considerations while competing in globally. Firms require setting different and appropriate prices of their products for each of the markets they operate in. The price of a...
Published by: IGI Global Scientific Publishing
COVID-19 Vaccine Global Information Management Through Bibliometrics
Vaccination is nowadays the most used option to stem the covid-19 pandemic. The global impact of the pandemic has triggered an unprecedented frenzy for research axis related to COVID-19 vaccine. Since 2019, the volume of...
Published by: IGI Global Scientific Publishing
Multidisciplinary research priorities for the COVID-19 pandemic
Emily A Holmes, Rory C O'Connor, V Hugh Perry, Irene Tracey, Simon Wessely, Louise Arseneault, Clive Ballard, Helen Christensen, Roxane Cohen Silver, Ian Everall, Tamsin Ford, Ann John, Thomas Kabir, Kate King, Ira Madan, Susan Michie, Andrew K Przybylski, Roz Shafran, Angela Sweeney, Carol M Worthman, Lucy Yardley, Katherine Cowan, Claire Cope, Matthew Hotopf, Ed Bullmore
May 19, 2020
The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health. We explore the psychological, social, and neuroscientific effects of COVID-19...
Impact of COVID-19-related disruptions to measles, meningococcal A, and yellow fever vaccination in 10 countries.
Katy AM Gaythorpe, Kaja Abbas, John Huber, Andromachi Karachaliou, Niket Thakkar, Kim Woodruff, Xiang Li, Susy Echeverria-Londono, VIMC Working Group on COVID-19 Impact on Vaccine Preventable Disease, Matthew Ferrari, Michael L Jackson, Kevin McCarthy, T Alex Perkins, Caroline Trotter, Mark Jit
Sep 13, 2021
BACKGROUND: Childhood immunisation services have been disrupted by the COVID-19 pandemic. WHO recommends considering outbreak risk using epidemiological criteria when deciding whether to conduct preventive vaccination campaigns...
covid-19 EPIDEMIOLOGY Global Health human Mathematical modelling Measles Medicine Meningococcal disease Vaccination Yellow Fever Adolescent Adult Africa Bangladesh covid-19 Child Child Preschool Disease Outbreaks Humans Immunization Programs Infant Measles Measles Vaccine Meningococcal Infections Meningococcal Vaccines Pandemics Risk Assessment SARS-CoV-2 Vaccination Yellow Fever Yellow Fever Vaccine Young Adult
Decreasing hospital burden of COVID-19 during the first wave in Regione Lombardia
Francesca Maria Grosso, Anne Margaret Presanis, Kevin Kunzmann, Chris Jackson, Alice Corbella, Giacomo Grasselli, Aida Andreassi, Annalisa Bodina, Maria Gramegna, Silvana Castaldi, Danilo Cereda, Daniela De Angelis, Covid-19 Lombardy Working Group
Jan 04, 2022
BACKGROUND: The aim of this study is to quantify the hospital burden of COVID-19 during the first wave and how it changed over calendar time; to interpret the results in light of the emergency measures introduced to manage the...
Key questions for modelling COVID-19 exit strategies
Robin N Thompson, T Déirdre Hollingsworth, Valerie Isham, Daniel Arribas-Bel, Ben Ashby, Tom Britton, Peter Challenor, Lauren H K Chappell, Hannah Clapham, Nik J Cunniffe, A Philip Dawid, Christl A Donnelly, Rosalind M Eggo, Sebastian Funk, Nigel Gilbert, Paul Glendinning, Julia R Gog, William S Hart, Hans Heesterbeek, Thomas House, Matt Keeling, István Z Kiss, Mirjam E Kretzschmar, Alun L Lloyd, Emma S McBryde, James M McCaw, Trevelyan J McKinley, Joel C Miller, Martina Morris, Philip D O'Neill, Kris V Parag, Carl A B Pearson, Lorenzo Pellis, Juliet R C Pulliam, Joshua V Ross, Gianpaolo Scalia Tomba, Bernard W Silverman, Claudio J Struchiner, Michael J Tildesley, Pieter Trapman, Cerian R Webb, Denis Mollison, Olivier Restif
Aug 12, 2020
Combinations of intense non-pharmaceutical interventions (lockdowns) were introduced worldwide to reduce SARS-CoV-2 transmission. Many governments have begun to implement exit strategies that relax restrictions while...
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