Search
Results: 926
Ge/Si and Ge Isotope Fractionation During Glacial and Non-glacial Weathering
Glacial environments offer the opportunity to study the incipient stages of chemical weathering due to the high availability of finely ground sediments, low water temperatures, and typically short rock-water interaction...
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Jan 22, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
Structural properties of liquid Ge<sub>2</sub>Se<sub>3</sub>
Sébastien Le Roux, Anita Zeidler, Philip S Salmon, Mauro Boero, Matthieu Micoulaut, Carlo Massobrio
Jan 01, 0001
The structural properties of liquid Ge2Se3 were investigated by first-principles molecular dynamics using the Becke-Lee-Yang-Parr scheme for the treatment of the exchange-correlation functional in density functional theory. Our...
Structural properties of liquid Ge<sub>2</sub>Se<sub>3</sub>
Sébastien Le Roux, Anita Zeidler, Philip S Salmon, Mauro Boero, Matthieu Micoulaut, Carlo Massobrio
Jan 01, 0001
The structural properties of liquid Ge2Se3 were investigated by first-principles molecular dynamics using the Becke-Lee-Yang-Parr scheme for the treatment of the exchange-correlation functional in density functional theory. Our...
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation.
Sympathetic neurons depend on NGF binding to TrkA for their survival during vertebrate development. NGF deprivation initiates a transcription-dependent apoptotic response, which is suggested to require activation of the...
Animals Apoptosis Base Sequence Brain-Derived Neurotrophic Factor Cells Cultured Cycloheximide Gene Expression Regulation Developmental Genetic Vectors Green Fluorescent Proteins Immunohistochemistry Indicators and Reagents Integrases Luminescent Proteins Mice Mice Knockout Mutation Nerve Growth Factor Neurons Protein Synthesis Inhibitors Proto-Oncogene Proteins c-jun Receptor Nerve Growth Factor Superior Cervical Ganglion Transfection Viral Proteins
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Mar 15, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Face Dependence of Schottky Barriers Heights of Silicides and Germanides on Si and Ge.
Density functional supercell calculations of the Schottky barrier heights (SBH) of metal germanides and silicides on Si or Ge find that these vary with the facet, unlike those of elemental metals. In addition, silicides and...
Comment on " In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates".
Colm J McGinnity, Erik Årstad, Katherine Beck, David J Brooks, Jonathan P Coles, John S Duncan, Marian Galovic, Rainer Hinz, Ella Hirani, Oliver D Howes, Paul A Jones, Matthias J Koepp, Feng Luo, Daniela A Riaño Barros, Nisha Singh, William Trigg, Alexander Hammers
Oct 03, 2018
Schoenberger and colleagues ( Schoenberger et al. ( 2018 ) ACS Chem. Neurosci. 9 , 298 - 305 ) recently reported attempts to demonstrate specific binding of the positron emission tomography (PET) radiotracer, [18F]GE-179, to...
Users' Continuance Intention to Use a Mobile Application
This study examines factors that influence users' continuance intention to use a mobile application. There exist few empirical researches focused solely on examining factors influencing users' continuance intention of using...
Published by: IGI Global Scientific Publishing
Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI.
Marius de Groot, Neel Patel, Roido Manavaki, Robert L Janiczek, Mats Bergstrom, Andrew Östör, Danielle Gerlag, Alexandra Roberts, Martin J Graves, Yakshitha Karkera, Disala Fernando, Prafull Mistry, Adam Walker, Nicolas Wisniacki, Tim D Fryer, Pilar Jimenez-Royo
Feb 13, 2020
PURPOSE: While the aetiology of rheumatoid arthritis (RA) remains unclear, many of the inflammatory components are well characterised. For diagnosis and therapy evaluation, in vivo insight into these processes would be valuable....
Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI.
Marius de Groot, Neel Patel, Roido Manavaki, Robert L Janiczek, Mats Bergstrom, Andrew Östör, Danielle Gerlag, Alexandra Roberts, Martin J Graves, Yakshitha Karkera, Disala Fernando, Prafull Mistry, Adam Walker, Nicolas Wisniacki, Tim D Fryer, Pilar Jimenez-Royo
Jan 27, 2020
PURPOSE:While the aetiology of rheumatoid arthritis (RA) remains unclear, many of the inflammatory components are well characterised. For diagnosis and therapy evaluation, in vivo insight into these processes would be valuable....
Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18 F-GE-180 and comparison with 18 F-FDG and DCE-MRI
Marius de Groot, Neel Patel, Roido Manavaki, Robert L. Janiczek, Mats Bergstrom, Andrew Östör, Danielle Gerlag, Alexandra Roberts, Martin J. Graves, Yakshitha Karkera, Disala Fernando, Prafull Mistry, Adam Walker, Nicolas Wisniacki, Tim D. Fryer, Pilar Jimenez-Royo
Dec 22, 2020
Abstract: Purpose: While the aetiology of rheumatoid arthritis (RA) remains unclear, many of the inflammatory components are well characterised. For diagnosis and therapy evaluation, in vivo insight into these processes would be...
Structure of crystalline and amorphous materials in the NASICON system Na<sub>1+x</sub>Al<sub>x</sub>Ge<sub>2- x</sub>(PO<sub>4</sub>)<sub>3</sub>
Lawrence V.D. Gammond, Henry Auer, Rita Mendes Da Silva, Anita Zeidler, Jairo F. Ortiz-Mosquera, Adriana M. Nieto-Muñoz, Ana Candida M. Rodrigues, Igor D'Anciães Almeida Silva, Hellmut Eckert, Chris J. Benmore, Philip S. Salmon
Aug 21, 2021
The structure of crystalline and amorphous materials in the sodium (Na) super-ionic conductor system Na1+xAlxGe2-x(PO4)3 with x = 0, 0.4, and 0.8 was investigated by combining (i) neutron and x-ray powder diffraction and...
Structure of crystalline and amorphous materials in the NASICON system Na<sub>1+x</sub>Al<sub>x</sub>Ge<sub>2- x</sub>(PO<sub>4</sub>)<sub>3</sub>
Lawrence V.D. Gammond, Henry Auer, Rita Mendes Da Silva, Anita Zeidler, Jairo F. Ortiz-Mosquera, Adriana M. Nieto-Muñoz, Ana Candida M. Rodrigues, Igor D'Anciães Almeida Silva, Hellmut Eckert, Chris J. Benmore, Philip S. Salmon
Aug 21, 2021
The structure of crystalline and amorphous materials in the sodium (Na) super-ionic conductor system Na1+xAlxGe2-x(PO4)3 with x = 0, 0.4, and 0.8 was investigated by combining (i) neutron and x-ray powder diffraction and...
Systematic characterization of mutations altering protein degradation in human cancers.
Collin Tokheim, Xiaoqing Wang, Richard T Timms, Boning Zhang, Elijah L Mena, Binbin Wang, Cynthia Chen, Jun Ge, Jun Chu, Wubing Zhang, Stephen J Elledge, Myles Brown, X Shirley Liu
Feb 11, 2021
The ubiquitin-proteasome system (UPS) is the primary route for selective protein degradation in human cells. The UPS is an attractive target for novel cancer therapies, but the precise UPS genes and substrates important for...
High-temperature phase transitions in dense germanium.
Liam C Kelsall, Miriam Peña-Alvarez, Miguel Martinez-Canales, Jack Binns, Chris J Pickard, Philip Dalladay-Simpson, Ross T Howie, Eugene Gregoryanz
Apr 08, 2021
Through a series of high-pressure x-ray diffraction experiments combined with in situ laser heating, we explore the pressure-temperature phase diagram of germanium (Ge) at pressures up to 110 GPa and temperatures exceeding 3000...
Activation and Monitoring of mtDNA Damage in Cancer Cells via the "proton-Triggered" Decomposition of an Ultrathin Nanosheet
Jun W. Liu, Yong G. Yang, Kui Wang, Ge Wang, Cong C. Shen, Yue H. Chen, Yu F. Liu, Tony D. James, Kai Jiang, Hua Zhang
Jan 27, 2021
Mitochondrial DNA (mtDNA) damage is a very important molecular event, which has significant effects on living organisms. Therefore, a particularly important challenge for biomaterials research is to develop functionalized...
Role of Slogan in Political Mobilisation in Nigeria
Ibrahim Lawal Ahmed
Jun 30, 2021
One of the tasks of political parties in the modern democracy is political mobilization. In a competitive democracy political mobilization requires good strategy which demands exploitation of all the tools of mobilization....
Published by: Department of History, University of Karachi
Topological Ordering and Viscosity in the Glass-Forming Ge-Se System
The topological ordering of the network structure in vitreous GexSe1-x was investigated across most of the glass-forming region (0 < x < 0.4) by using high resolution neutron diffraction to measure...
Topological Ordering and Viscosity in the Glass-Forming Ge-Se System
The topological ordering of the network structure in vitreous GexSe1-x was investigated across most of the glass-forming region (0 < x < 0.4) by using high resolution neutron diffraction to measure...
Activation and Monitoring of mtDNA Damage in Cancer Cells via the "proton-Triggered" Decomposition of an Ultrathin Nanosheet
Jun W. Liu, Yong G. Yang, Kui Wang, Ge Wang, Cong C. Shen, Yue H. Chen, Yu F. Liu, Tony D. James, Kai Jiang, Hua Zhang
Jan 27, 2021
Mitochondrial DNA (mtDNA) damage is a very important molecular event, which has significant effects on living organisms. Therefore, a particularly important challenge for biomaterials research is to develop functionalized...
Experiential Metafunctional Analysis of Liu Xijun's “Bei Chou Ge” and Its English Versions
Cheng Huaming
Jan 01, 2023
This paper attempts to analyze and compare transitivity processes of “Bei Chou Ge” and its five English versions from the perspective of experiential function of Halliday's systemic-functional linguistics and makes a comment on...
Published by: IGI Global Scientific Publishing
Revealing the intrinsic nature of the mid-gap defects in amorphous Ge 2 Sb 2 Te 5
Abstract: Understanding the relation between the time-dependent resistance drift in the amorphous state of phase-change materials and the localised states in the band gap of the glass is crucial for the development of memory...
|
|< |
< |
1 |