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A Novel Task-Scheduling Algorithm of Cloud Computing Based on Particle Swarm Optimization
With the characteristics of low cost, high availability, and scalability, cloud computing has become a high demand platform in the field of information technology. Due to the dynamic and diversity of cloud computing system, the...
Published by: IGI Global Scientific Publishing
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Jan 22, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun
Daniel Baxter, Samuel Perry, Timothy Hill, Woan Kok, Nathan Zaccai, Leo Brady, David Fairlie, Jody Mason
Aug 18, 2017
The oncogenic transcription factor Activator Protein-1 (AP-1) is a DNA binding protein that assembles through dimerization of Fos and Jun protein subunits, their leucine-rich helical sequences entwining into a coiled coil...
c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation.
Sympathetic neurons depend on NGF binding to TrkA for their survival during vertebrate development. NGF deprivation initiates a transcription-dependent apoptotic response, which is suggested to require activation of the...
Animals Apoptosis Base Sequence Brain-Derived Neurotrophic Factor Cells Cultured Cycloheximide Gene Expression Regulation Developmental Genetic Vectors Green Fluorescent Proteins Immunohistochemistry Indicators and Reagents Integrases Luminescent Proteins Mice Mice Knockout Mutation Nerve Growth Factor Neurons Protein Synthesis Inhibitors Proto-Oncogene Proteins c-jun Receptor Nerve Growth Factor Superior Cervical Ganglion Transfection Viral Proteins
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun.
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Mar 15, 2021
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that...
Agent-based coordinated operation strategy for active distribution network with distributed energy resources
Shuai Hu, Yue Xiang, Junyong Liu, Chenghong Gu, Xin Zhang, Yuting Tian, Zhixuan Liu, Jun Xiong
Jul 01, 2019
With the development of distributed energy resources (DERs) and the increasing flexibility in active distribution networks (ADNs), the economic operation of ADN coordinating both generation and demand sides is required to be...
Agent-based Operation Strategy for Active Distribution Network Considering Energy Storage and Flexible Load
Yue Xiang, Junyong Liu, Shuai Hu, Yuting Tian, Chenghong Gu, Jun Xiong, Xin Zhang, Zhixuan Liu
Nov 29, 2018
With the development of distributed energy resources (DERs) and the increasing flexibility in active distribution networks (ADNs), the economic operation of ADN components on both generation and demand sides to improve power...
Agent-based coordinated operation strategy for active distribution network with distributed energy resources
Shuai Hu, Yue Xiang, Junyong Liu, Chenghong Gu, Xin Zhang, Yuting Tian, Zhixuan Liu, Jun Xiong
Jul 01, 2019
With the development of distributed energy resources (DERs) and the increasing flexibility in active distribution networks (ADNs), the economic operation of ADN coordinating both generation and demand sides is required to be...
Agent-based Operation Strategy for Active Distribution Network Considering Energy Storage and Flexible Load
Yue Xiang, Junyong Liu, Shuai Hu, Yuting Tian, Chenghong Gu, Jun Xiong, Xin Zhang, Zhixuan Liu
Nov 29, 2018
With the development of distributed energy resources (DERs) and the increasing flexibility in active distribution networks (ADNs), the economic operation of ADN components on both generation and demand sides to improve power...
Improved Yolov5 and Image Morphology Processing Based on UAV Platform for Dike Health Inspection
Dike health inspection is crucial in river channel regulating. The conventional manual collapse inspection is inefficient and costly so that the unmanned aerial vehicle (UAV)-based inspection has been widely applied. However...
Published by: IGI Global Scientific Publishing
BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers.
Rahul Roychoudhuri, David Clever, Peng Li, Yoshiyuki Wakabayashi, Kylie M Quinn, Christopher A Klebanoff, Yun Ji, Madhusudhanan Sukumar, Robert L Eil, Zhiya Yu, Rosanne Spolski, Douglas C Palmer, Jenny H Pan, Shashank J Patel, Derek C Macallan, Giulia Fabozzi, Han-Yu Shih, Yuka Kanno, Akihiko Muto, Jun Zhu, Luca Gattinoni, John J O'Shea, Klaus Okkenhaug, Kazuhiko Igarashi, Warren J Leonard, Nicholas P Restifo
Jun 27, 2018
T cell antigen receptor (TCR) signaling drives distinct responses depending on the differentiation state and context of CD8(+) T cells. We hypothesized that access of signal-dependent transcription factors (TFs) to enhancers is...
Adaptive Immunity Animals Basic-Leucine Zipper Transcription Factors CD8-Positive T-Lymphocytes Cell Differentiation Cells Cultured Enhancer Elements Genetic Gene Expression Regulation Immunologic Memory Lymphocyte Activation Mice Mice Inbred C57BL Mice Knockout Oncogene Protein p65(gag-jun) Signal Transduction Transcription Factor AP-1 Vaccinia vaccinia virus
A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair.
Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco-Serna, Juana Gallar, Peter Arthur-Farraj, Jose A Gomez-Sanchez, Hugo Cabedo
Feb 17, 2022
The class IIa histone deacetylases (HDACs) have pivotal roles in the development of different tissues. Of this family, Schwann cells express Hdac4, 5 and 7 but not Hdac9. Here we show that a transcription factor regulated...
An M-Learning Model in the Context of the Blended Synchronous Learning Environment
Mobile learning provides more flexibility and holds considerable promise for improving the learning process and promoting lifelong learning. In order to reduce the sense of isolation felt by the learners, this research...
Published by: IGI Global Scientific Publishing
Exploration on Innovation Path of Precise Ideological and Political Work in Colleges and Universities Under the Background of Big Data Driving
Xiong Luo
Jan 01, 2024
However, although existing models for evaluating the effectiveness of universities provide a large number of modeling solutions, it is difficult to objectively evaluate dynamic coefficients based on the differences in precision...
Published by: IGI Global Scientific Publishing
Mechanics of neural tube morphogenesis.
The neural tube is an important model system of morphogenesis representing the developmental module of out-of-plane epithelial deformation. As the embryonic precursor of the central nervous system, the neural tube also holds...
Room Temperature Ferrimagnetism and Ferroelectricity in Strained, Thin Films of BiFe0.5Mn0.5O3.
Eun-Mi Choi, Thomas Fix, Ahmed Kursumovic, Christy J Kinane, Darío Arena, Suman-Lata Sahonta, Zhenxing Bi, Jie Xiong, Li Yan, Jun-Sik Lee, Haiyan Wang, Sean Langridge, Young-Min Kim, Albina Y Borisevich, Ian MacLaren, Quentin M Ramasse, Mark G Blamire, Quanxi Jia, Judith L Macmanus-Driscoll
Sep 12, 2014
Risk Assessment Modeling of Urban Railway Investment and Financing Based on Improved SVM Model for Advanced Intelligent Systems
A risk assessment method for urban railway investment and financing based on an improved SVM model under big data is proposed. First, the inner product in the traditional SVM is replaced by a kernel function to obtain a more...
Published by: IGI Global Scientific Publishing
A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco-Serna, Juana Gallar Gallar, Peter Arthur-Farraj, Jose Gomez-Sanchez, Hugo Cabedo
Feb 25, 2022
The class IIa histone deacetylases (HDACs) have pivotal roles in the development of different tissues. Of this family, Schwann cells express Hdac4, 5 and 7 but not Hdac9. Here we show that a transcription factor regulated...
Generalized Ordered Weighted Simplified Neutrosophic Cosine Similarity Measure for Multiple Attribute Group Decision Making
Jun Ye
Jan 01, 2020
The paper proposes a generalized ordered weighted simplified neutrosophic cosine similarity (GOWSNCS) measure by combining the cosine similarity measure of simplified neutrosophic sets (SNSs) with the generalized ordered...
Published by: IGI Global Scientific Publishing
The Source of the Current of Injury
Jacques Loeb and Reinhard Beutner. The source of the current of injury
Reprinted from Science, 1912, Jun 21, 35(912):970-971
Published by: Rockefeller University
Facile synthesis of crack-free metal-organic framework films on alumina by a dip-coating route in the presence of polyethylenimine
A facile polyethylenimine (PEI)-assisted dip-coating method allows crack-free films of MIL-101(Cr) and MIL-101(Cr)-NH2 to be prepared on alumina supports. The presence of PEI enhances the selectivity of the films...
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