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Thought and Language
Lourdes Flamarique
May 04, 2009
Published by: Memorial University of Newfoundland
Thought and Language
Lourdes Flamarique
May 04, 2009
Published by: Memorial University of Newfoundland
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
Theoretical and Practical Concerns Regarding Digital Texts in Literacy Instruction
The role of literacy and learning is easily incorporated into many areas of using technology in the classroom. The purpose of this book chapter is to share results from a research study that provides a framework for teachers to...
Published by: IGI Global Scientific Publishing
Short-Term Response of Cytosolic N O 3 - to Inorganic Carbon Increase in Posidonia oceanica Leaf Cells.
The concentration of CO2 in the atmosphere has increased over the past 200 years and is expected to continue rising in the next 50 years at a rate of 3 ppm·year-1. This increase has led to a decrease in seawater pH that has...
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
Persisting benefits 12-18 months after discontinuation of pubertal metformin therapy in low birthweight girls.
BACKGROUND: Discontinuation of metformin therapy, if started beyond menarche in adolescents or young women with hyperinsulinaemia following low birthweight, is rapidly followed by rebound deteriorations in body fat, insulin...
Short-Term Response of Cytosolic N O 3 − to Inorganic Carbon Increase in Posidonia oceanica Leaf Cells
The concentration of CO2 in the atmosphere has increased over the past 200 years and is expected to continue rising in the next 50 years at a rate of 3 ppm·year−1. This increase has led to a decrease in seawater pH that has...
Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia.
Ana Rivera-Barahona, Esmeralda Alonso-Barroso, Belén Pérez, Michael P Murphy, Eva Richard, Lourdes R Desviat
Jun 18, 2018
Oxidative stress contributes to the pathogenesis of propionic acidemia (PA), a life threatening disease caused by the deficiency of propionyl CoA-carboxylase, in the catabolic pathway of branched-chain amino acids, odd-number...
Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea.
Jose M Bermúdez-Muñoz, Adelaida M Celaya, Ángela García-Mato, Daniel Muñoz-Espín, Lourdes Rodríguez-de la Rosa, Manuel Serrano, Isabel Varela-Nieto
Oct 29, 2021
Stress-activated protein kinases (SAPK) are associated with sensorineural hearing loss (SNHL) of multiple etiologies. Their activity is tightly regulated by dual-specificity phosphatase 1 (DUSP1), whose loss of function leads to...
The Transcription Factor ERG Regulates Super-Enhancers Associated with an Endothelial-Specific Gene Expression Program
Viktoria Kalna, Youwen Yang, Claire Peghaire, Karen Frudd, Rebecca Hannah, Aarti V Shah, Lourdes Osuna Almagro, Joseph J Boyle, Berthold Göttgens, Jorge Ferrer, Anna M Randi, Graeme M Birdsey
Apr 03, 2019
Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed-batch fermentation.
M Lourdes Velez-Suberbie, Stephen A Morris, Kawaljit Kaur, John M Hickey, Sangeeta B Joshi, David B Volkin, Daniel G Bracewell, Tarit K Mukhopadhyay
Aug 26, 2020
To meet the challenges of global health, vaccine design and development must be reconsidered to achieve cost of goods as low as 15¢ per dose. A new recombinant protein-based rotavirus vaccine candidate derived from...
Acute Pharmacological Effects and Oral Fluid Biomarkers of the Synthetic Cannabinoid UR-144 and THC in Recreational Users.
Nunzia La Maida, Esther Papaseit, Lucia Martínez, Clara Pérez-Mañá, Lourdes Poyatos, Manuela Pellegrini, Simona Pichini, Roberta Pacifici, Mireia Ventura, Liliana Galindo, Francesco Paolo Busardò, Magí Farré
Mar 26, 2021
Synthetic cannabinoids (SCs) are one of the most frequent classes of new psychoactive substances monitored by the EU Early Warning System and World Health Organization. UR-144 is a SC with a relative low affinity for the CB1...
Modulation of the potassium channel KcsA by anionic phospholipids
José A Poveda, A Marcela Giudici, M Lourdes Renart, Oscar Millet, Andrés Morales, José M González-Ros, Victoria Oakes, Simone Furini, Carmen Domene
Oct 01, 2019
The role of arginines R64 and R89 at non-annular lipid binding sites of KcsA, on the modulation of channel activity by anionic lipids has been investigated. In wild-type (WT) KcsA reconstituted into asolectin lipid membranes...
Ion channel inactivation Ion channel kinetics Membrane lipid-protein interactions molecular dynamics simulations Patch-clamp recordings /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
Methylation of the C19MC microRNA locus in the placenta
Anna Prats-Puig, Sílvia Xargay-Torrent, Gemma Carreras-Badosa, Berta Mas-Parés, Judit Bassols, Clive J Petry, Michael Girardot, Francis D E Zegher, Lourdes Ibáñez, David B Dunger, Robert Feil, Abel López-Bermejo
Jul 12, 2019
Lorcaserin improves glycemic control via a melanocortin neurocircuit.
Luke K Burke, Emmanuel Ogunnowo-Bada, Teodora Georgescu, Claudia Cristiano, Pablo B Martinez de Morentin, Lourdes Valencia Torres, Giuseppe D'Agostino, Christine Riches, Nicholas Heeley, Yue Ruan, Marcelo Rubinstein, Malcolm J Low, Martin G Myers, Justin J Rochford, Mark L Evans, Lora K Heisler
Sep 11, 2018
OBJECTIVE: The increasing prevalence of type 2 diabetes (T2D) and associated morbidity and mortality emphasizes the need for a more complete understanding of the mechanisms mediating glucose homeostasis to accelerate the...
5-HT2C receptor Hypothalamus Lorcaserin Melanocortin4 receptor (Mc4r) Pro-opiomelanocortin (POMC) Type 2 diabetes Animals Benzazepines Blood Glucose Body Weight Diabetes mellitus Type 2 Disease Models Animal Eating Energy Metabolism Glucose Glucose Tolerance Test Homeostasis Humans Insulin Resistance Melanocortins Mice Mice Transgenic obesity Receptor Serotonin 5-HT2C Receptors Melanocortin Weight Loss
Modulation of the potassium channel KcsA by anionic phospholipids
José A Poveda, A Marcela Giudici, M Lourdes Renart, Oscar Millet, Andrés Morales, José M González-Ros, Victoria Oakes, Simone Furini, Carmen Domene
Oct 01, 2019
The role of arginines R64 and R89 at non-annular lipid binding sites of KcsA, on the modulation of channel activity by anionic lipids has been investigated. In wild-type (WT) KcsA reconstituted into asolectin lipid membranes...
Ion channel inactivation Ion channel kinetics Membrane lipid-protein interactions molecular dynamics simulations Patch-clamp recordings /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology
Acute Pharmacological Effects and Oral Fluid Concentrations of the Synthetic Cannabinoids JWH-122 and JWH-210 in Humans After Self-Administration
Lucia Martínez, Nunzia La Maida, Esther Papaseit, Clara Pérez-Mañá, Lourdes Poyatos, Manuela Pellegrini, Simona Pichini, Mireia Ventura, Liliana Galindo, Francesco Paolo Busardò, Magí Farré
Sep 08, 2021
Synthetic cannabinoids (SCs) are a group of new psychoactive drugs used recreationally with potential health risks. They are monitored by the EU Early Warning System since 2010 due to severe adverse effects on consumers. JWH-122...
Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS.
Nunzia La Maida, Manuela Pellegrini, Esther Papaseit, Clara Pérez-Mañá, Lourdes Poyatos, Mireia Ventura, Liliana Galindo, Francesco Paolo Busardò, Simona Pichini, Magí Farré, Emilia Marchei
Dec 11, 2020
The consumption of synthetic cannabinoids (SCs) has significantly increased in the last decade and the analysis of SCs and their metabolites in human specimens is gaining interest in clinical and forensic toxicology. A pilot...
Pilgrimage and Visual Genre
As Roman Catholics gained confidence in twentieth-century Scotland, they revived pre-Reformation shrines and pilgrimages and created new shrines with transnational connections to the modern Catholic world. Three sites in this...
Pilgrimage and Visual Genre
As Roman Catholics gained confidence in twentieth-century Scotland, they revived pre-Reformation shrines and pilgrimages and created new shrines with transnational connections to the modern Catholic world. Three sites in this...
Complement component 3 as biomarker of disease activity and cardiometabolic risk factor in rheumatoid arthritis and spondyloarthritis.
Iván Arias de la Rosa, Pilar Font, Alejandro Escudero-Contreras, María Dolores López-Montilla, Carlos Pérez-Sánchez, María Carmen Ábalos-Aguilera, Lourdes Ladehesa-Pineda, Alejandro Ibáñez-Costa, Carmen Torres-Granados, Yolanda Jimenez-Gomez, Alejandra Patiño-Trives, María Luque-Tévar, María Carmen Castro-Villegas, Jerusalem Calvo-Gutiérrez, Rafaela Ortega-Castro, Chary López-Pedrera, Eduardo Collantes-Estévez, Nuria Barbarroja
Oct 23, 2020
Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation.
Delphine Cuchet-Lourenço, Davide Eletto, Changxin Wu, Vincent Plagnol, Olivier Papapietro, James Curtis, Lourdes Ceron-Gutierrez, Chris M Bacon, Scott Hackett, Badr Alsaleem, Mailis Maes, Miguel Gaspar, Ali Alisaac, Emma Goss, Eman AlIdrissi, Daniela Siegmund, Harald Wajant, Dinakantha Kumararatne, Mofareh S AlZahrani, Peter D Arkwright, Mario Abinun, Rainer Doffinger, Sergey Nejentsev
Sep 08, 2018
RIPK1 (receptor-interacting serine/threonine kinase 1) is a master regulator of signaling pathways leading to inflammation and cell death and is of medical interest as a drug target. We report four patients from three unrelated...
The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling.
Graeme M Birdsey, Aarti V Shah, Neil Dufton, Louise E Reynolds, Lourdes Osuna Almagro, Youwen Yang, Irene M Aspalter, Samia T Khan, Justin C Mason, Elisabetta Dejana, Berthold Göttgens, Kairbaan Hodivala-Dilke, Holger Gerhardt, Ralf H Adams, Anna M Randi
Feb 16, 2015
Animals Antigens CD Blotting Western Cadherins Cells Cultured Chromatin Immunoprecipitation Endothelium Vascular Female Frizzled Receptors Human Umbilical Vein Endothelial Cells Humans Integrases Lung Mice Mice Transgenic Neovascularization Physiologic Oncogene Proteins Pregnancy Real-Time Polymerase Chain Reaction Signal Transduction Transcription Factors Transcriptional Regulator ERG Vascular Endothelial Growth Factor A Wnt Proteins beta Catenin
Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing.
Lourdes Ortiz-Fernández, Elio G Carmona, Martin Kerick, Paul Lyons, Francisco David Carmona, Raquel López Mejías, Chiea Chuen Khor, Peter C Grayson, Enrico Tombetti, Lindi Jiang, Haner Direskeneli, Guher Saruhan-Direskeneli, José-Luis Callejas-Rubio, Augusto Vaglio, Carlo Salvarani, Jose Hernández-Rodríguez, Maria Cinta Cid, Ann W Morgan, Peter A Merkel, David Burgner, Kenneth GC Smith, Miguel Angel Gonzalez-Gay, Amr H Sawalha, Javier Martin, Ana Marquez
Feb 21, 2023
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