Search

This chapter presents an international state-of-the-art literature review of abusive trolling experienced by workers in the creative and cultural industries (CCIs), bringing target experiences and organizational/occupational...

Cyber Behavior Media and Communications Digital Communications Social Sciences and Humanities Computer Science and Information Technology

This chapter presents an international state-of-the-art literature review of abusive trolling experienced by workers in the creative and cultural industries (CCIs), bringing target experiences and organizational/occupational...

Human Aspects of Business Business and Management Human Aspects of Business Social Sciences and Humanities

UCTD diagnostic delays medical support misdiagnoses Patient views Patient–physician interaction Quality of life Symptoms Systemic Lupus Erythematosus

Lupus is a multi-system autoimmune rheumatic disease with increased morbidity and mortality. Some manifestations are life-threatening with many aspects of living with the disease, difficulties in diagnosis and accessing...

Holistic care lupus Misdiagnosis Patient views Patient–physician interaction Quality of life Adaptation Physiological Diagnostic Errors Female Health Knowledge Attitudes practice Health Services Accessibility Humans Lupus Erythematosus Systemic Physician-Patient Relations qualitative research Quality of life resilience Psychological social support United Kingdom

OBJECTIVE: To compare the responsiveness of BILAG-2004 and SLEDAI-2000 disease activity indices and determine if there was any added value in combining BILAG-2004, BILAG System Tally (BST) or simplified BST (sBST) with...

OBJECTIVES: The Covid-19 pandemic necessitated a rapid global transition towards telemedicine; yet much remains unknown about telemedicine's acceptability and safety in rheumatology. To help address this gap and inform practice...

digital technology in medicine mixed-methods pandemic patient–physician interactions rare autoimmune rheumatic diseases Rheumatology Telemedicine covid-19 Humans Pandemics Rheumatology Surveys and Questionnaires Telemedicine

OBJECTIVE: To compare the responsiveness of BILAG-2004 and SLEDAI-2000 disease activity indices and determine if there was any added value in combining BILAG-2004, BILAG System Tally (BST) or simplified BST (sBST) with...

Background

Patients with non-severe ANCA-associated vasculitis (AAV) are often prescribed immunosuppressive medications that are associated with severe side effects and a reduced quality of life. There is an unmet need...

AAV Vasculitis Hydroxychloroquine Prednisolone ANCA Auto-immune conditions Humans Immunosuppressive Agents Antibodies Antineutrophil Cytoplasmic Treatment Outcome Double-Blind Method Quality of life Multicenter Studies as Topic Randomized Controlled Trials as Topic Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis covid-19 SARS-CoV-2

The current global pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has taken a substantial number of lives across the world. Although few vaccines have been rolled-out, a number of vaccine candidates...

SARS-CoV-2 bio-informatics immuno-informatics Peptide vaccine COVID-19 Vaccines Epitopes B-Lymphocyte Epitopes T-Lymphocyte Humans Molecular Docking Simulation SARS-CoV-2 vaccines Subunit

BACKGROUND: Patients with non-severe ANCA-associated vasculitis (AAV) are often prescribed immunosuppressive medications that are associated with severe side effects and a reduced quality of life. There is an unmet need for...

AAV ANCA Auto-immune conditions Hydroxychloroquine Prednisolone Vasculitis

OBJECTIVES: To describe the baseline characteristics of SLE patients requiring biologic therapy in the UK and to explore short term efficacy and infection rates associated with rituximab (RTX) use. METHODS: Patients commencing...

Adult Antirheumatic Agents Biological Products Case-Control Studies Female Glucocorticoids Humans Infections Lupus Erythematosus Systemic Male Middle Aged Rituximab Severity of Illness Index Time Factors Treatment Outcome United Kingdom

Adult Ethnicity Humans Lupus Erythematosus Systemic Rheumatology Societies Medical

The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults.

assessment biologics Diagnosis EFFICACY immunosuppressants lupus Management Monitoring non-biologics Treatment Adult Disease Management Female Humans Lupus Erythematosus Systemic Male Middle Aged Rheumatology Symptom Assessment United Kingdom

B cells emerge from the bone marrow as transitional (TS) B cells that differentiate through T1, T2, and T3 stages to become naive B cells. We have identified a bifurcation of human B cell maturation from the T1 stage forming...

Adult Aged Blood Donors Case-Control Studies Cell Differentiation Cell Lineage Cells Cultured Female Gastrointestinal Tract Humans Immunoglobulin M Integrin beta Chains Interleukin-4 Receptor alpha Subunit Lupus Nephritis Lymphoid Tissue Male Middle Aged Phenotype Precursor Cells B-Lymphoid Sequence Analysis RNA Single-Cell Analysis Transcriptome Young Adult

OBJECTIVES: Relapsing polychondritis is a rare, multi-systemic and inflammatory condition of unknown origin. We currently lack a core set of measures to assess and follow damage in patients suffering from this condition. Our...

autoinflammatory diseases Damage index Relapsing polychondritis Adult Age Factors Cohort Studies Consensus Delphi Technique Disability Evaluation Expert Testimony Female Humans Internationality Male Middle Aged Polychondritis Relapsing Reproducibility of Results Risk Assessment Severity of Illness Index Sex Factors

The British Society for Rheumatology guideline for the management of systemic lupus erythematosus in adults: Executive Summary.

assessment biologics Diagnosis EFFICACY immunosuppressants lupus Management Monitoring non-biologics Treatment Adult Humans Lupus Erythematosus Systemic Rheumatology Societies Medical United Kingdom