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Liver Disease Detection
In recent times, intelligent predictive systems are showing greater levels of accuracy and effectiveness in early detection of the critical diseases of cancer in the liver, lungs, etc. Predictive models assist medical...
Published by: IGI Global Scientific Publishing
RETRACTED: Liver Disease Detection
Intelligent predictive systems are showing a greater level of accuracy and effectiveness in early detection of critical diseases like cancer and liver and lung disease. Predictive models assist medical practitioners in...
Published by: IGI Global Scientific Publishing
Bayesian Inference in Nonparametric Dynamic State-Space Models
We introduce state-space models where the functionals of the observational and the evolutionary equations are unknown, and treated as random functions evolving with time. Thus, our model is nonparametric and generalizes the...
Evolution of Highly Magnetic White Dwarfs by Field Decay and Cooling
Abstract
We investigate the luminosity suppression and its effect on the mass–radius relation and cooling evolution of highly magnetized white dwarfs. Based on the effect of...
“You Are What You Watch?”
Considering that today's youth are inadvertently exposed to violence in all forms of media and video games, research shows that this affects the psyche, subsequently manifesting in aggressive behaviour. This research paper...
Published by: IGI Global Scientific Publishing
Inner-View of Nanomaterial Incited Protein Conformational Changes
Nanoparticle bioreactivity critically depends upon interaction between proteins and nanomaterials (NM). The formation of the "protein corona" (PC) is the effect of such nanoprotein interactions. PC has a wide usage in...
Bayesian Inference in Nonparametric Dynamic State-Space Models
We introduce state-space models where the functionals of the observational and the evolutionary equations are unknown, and treated as random functions evolving with time. Thus, our model is nonparametric and generalizes the...
Amyloid-Like Aggregation in Native Protein and its Suppression in the Bio-Conjugated Counterpart
Prevention of protein aggregation and thus stabilization of proteins has large biological and biotechnological implications. Here we introduce Dynamic Light Scattering (DLS) and DLS-based microrheology to show how native...
Visible light photocatalysts from low-grade iron ore
Muthaimanoj Periyasamy, Sumanta Sain, Eliza Ghosh, Kellie J Jenkinson, Andrew EH Wheatley, Sudipta Mukhopadhyay, Arik Kar
Sep 10, 2021
Magnetite (Fe3O4) nanoparticles coated with dextrose and gluconic acid possessing both super-paramagnetism and excellent optical properties have been productively synthesized through a straightforward, efficient and cost...
Security/Privacy Perceptions in Patient Use of Online Medical Records
Data breaches expose individuals to economic, mental, and social trauma. Electronic health information of individuals not only includes reports of medical diagnosis, medication histories but also comprises personally...
Published by: IGI Global Scientific Publishing
Virulence Regulation and Innate Host Response in the Pathogenicity of Vibrio cholerae.
Thandavarayan Ramamurthy, Ranjan K Nandy, Asish K Mukhopadhyay, Shanta Dutta, Ankur Mutreja, Keinosuke Okamoto, Shin-Ichi Miyoshi, G Balakrish Nair, Amit Ghosh
Oct 14, 2020
The human pathogen Vibrio cholerae is the causative agent of severe diarrheal disease known as cholera. Of the more than 200 "O" serogroups of this pathogen, O1 and O139 cause cholera outbreaks and epidemics. The rest of the...
Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed-batch fermentation.
M Lourdes Velez-Suberbie, Stephen A Morris, Kawaljit Kaur, John M Hickey, Sangeeta B Joshi, David B Volkin, Daniel G Bracewell, Tarit K Mukhopadhyay
Aug 26, 2020
To meet the challenges of global health, vaccine design and development must be reconsidered to achieve cost of goods as low as 15¢ per dose. A new recombinant protein-based rotavirus vaccine candidate derived from...
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump.
Georg Schneditz, Joshua E Elias, Ester Pagano, M Zaeem Cader, Svetlana Saveljeva, Kathleen Long, Subhankar Mukhopadhyay, Maryam Arasteh, Trevor D Lawley, Gordon Dougan, Andrew Bassett, Tom H Karlsen, Arthur Kaser, Nicole C Kaneider
Dec 20, 2018
Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic.
Thandavarayan Ramamurthy, Agila Kumari Pragasam, Alyce Taylor-Brown, Robert C Will, Karthick Vasudevan, Bhabatosh Das, Sunil Kumar Srivastava, Goutam Chowdhury, Asish K Mukhopadhyay, Shanta Dutta, Balaji Veeraraghavan, Nicholas R Thomson, Naresh C Sharma, Gopinath Balakrish Nair, Yoshifumi Takeda, Amit Ghosh, Gordon Dougan, Ankur Mutreja
Aug 06, 2022
Cholera is a life-threatening infectious disease that remains an important public health issue in several low and middle-income countries. In 1992, a newly identified O139 Vibrio cholerae temporarily displaced the O1 serogroup....
Structural dynamics of a metal-organic framework induced by CO2 migration in its non-uniform porous structure.
Pu Zhao, Hong Fang, Sanghamitra Mukhopadhyay, Aurelia Li, Svemir Rudić, Ian J McPherson, Chiu C Tang, David Fairen-Jimenez, SC Edman Tsang, Simon AT Redfern
Feb 15, 2019
Stimuli-responsive behaviors of flexible metal-organic frameworks (MOFs) make these materials promising in a wide variety of applications such as gas separation, drug delivery, and molecular sensing. Considerable efforts have...
Vedantic variations in the presence of Europe
Ankur Barua
May 05, 2017
Abstract
We will offer in this essay an analytic overview of four texts from the second half of the nineteenth century which elaborated different variations on the Hindu dharma. These are Rajnarayan Basu’s Hindu...
The Rab32/BLOC-3-dependent pathway mediates host defense against different pathogens in human macrophages.
Massimiliano Baldassarre, Virtu Solano-Collado, Arda Balci, Rosa A Colamarino, Ivy M Dambuza, Delyth M Reid, Heather M Wilson, Gordon D Brown, Subhankar Mukhopadhyay, Gordon Dougan, Stefania Spanò
Feb 19, 2021
Macrophages provide a first line of defense against microorganisms, and while some mechanisms to kill pathogens such as the oxidative burst are well described, others are still undefined or unknown. Here, we report that the...
Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic.
Thandavarayan Ramamurthy, Agila Kumari Pragasam, Alyce Taylor-Brown, Robert C Will, Karthick Vasudevan, Bhabatosh Das, Sunil Kumar Srivastava, Goutam Chowdhury, Asish K Mukhopadhyay, Shanta Dutta, Balaji Veeraraghavan, Nicholas R Thomson, Naresh C Sharma, Gopinath Balakrish Nair, Yoshifumi Takeda, Amit Ghosh, Gordon Dougan, Ankur Mutreja
Jul 05, 2022
Cholera is a life-threatening infectious disease that remains an important public health issue in several low and middle-income countries. In 1992, a newly identified O139 Vibrio cholerae temporarily displaced the O1 serogroup....
Chromatin interactome mapping at 139 independent breast cancer risk signals.
Jonathan Beesley, Haran Sivakumaran, Mahdi Moradi Marjaneh, Luize G Lima, Kristine M Hillman, Susanne Kaufmann, Natasha Tuano, Nehal Hussein, Sunyoung Ham, Pamela Mukhopadhyay, Stephen Kazakoff, Jason S Lee, Kyriaki Michailidou, Daniel R Barnes, Antonis C Antoniou, Laura Fachal, Alison M Dunning, Douglas F Easton, Nicola Waddell, Joseph Rosenbluh, Andreas Möller, Georgia Chenevix-Trench, Juliet D French, Stacey L Edwards
Feb 08, 2020
BACKGROUND:Genome-wide association studies have identified 196 high confidence independent signals associated with breast cancer susceptibility. Variants within these signals frequently fall in distal regulatory DNA elements...
Published by: Genome biology
Chromatin interactome mapping at 139 independent breast cancer risk signals.
Jonathan Beesley, Haran Sivakumaran, Mahdi Moradi Marjaneh, Luize G Lima, Kristine M Hillman, Susanne Kaufmann, Natasha Tuano, Nehal Hussein, Sunyoung Ham, Pamela Mukhopadhyay, Stephen Kazakoff, Jason S Lee, Kyriaki Michailidou, Daniel R Barnes, Antonis C Antoniou, Laura Fachal, Alison M Dunning, Douglas F Easton, Nicola Waddell, Joseph Rosenbluh, Andreas Möller, Georgia Chenevix-Trench, Juliet D French, Stacey L Edwards
Aug 06, 2019
Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells.
Jessica L Forbester, Emily A Lees, David Goulding, Sally Forrest, Amy Yeung, Anneliese Speak, Simon Clare, Eve L Coomber, Subhankar Mukhopadhyay, Judith Kraiczy, Fernanda Schreiber, Trevor D Lawley, Robert EW Hancock, Holm H Uhlig, Matthias Zilbauer, Fiona Powrie, Gordon Dougan
Feb 15, 2019
Intestinal epithelial cells (IECs) play a key role in regulating immune responses and controlling infection. However, the direct role of IECs in restricting pathogens remains incompletely understood. Here, we provide evidence...
Non-coding RNAs underlie genetic predisposition to breast cancer
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Jun 06, 2020
C13orf31 (FAMIN) is a central regulator of immunometabolic function.
M Zaeem Cader, Katharina Boroviak, Qifeng Zhang, Ghazaleh Assadi, Sarah L Kempster, Gavin W Sewell, Svetlana Saveljeva, Jonathan W Ashcroft, Simon Clare, Subhankar Mukhopadhyay, Karen P Brown, Markus Tschurtschenthaler, Tim Raine, Brendan Doe, Edwin R Chilvers, Jules L Griffin, Nicole C Kaneider, R Andres Floto, Mauro D'Amato, Allan Bradley, Michael JO Wakelam, Gordon Dougan, Arthur Kaser
Aug 15, 2016
Adenosine Triphosphate Animals Arthritis Juvenile Bacteriolysis Cells Cultured Crohn Disease Energy Metabolism Fatty Acid Synthase Type I Genetic Predisposition to Disease Humans Infections Inflammasomes Intracellular Signaling Peptides and Proteins Leprosy Lipid Metabolism MACROPHAGES Mice Mice Inbred C57BL Mice Knockout NADPH Oxidases Oxidation-Reduction Polymorphism Single Nucleotide Proteins risk Shock Septic
Chromatin interactome mapping at 139 independent breast cancer risk signals
Jonathan Beesley, Haran Sivakumaran, Mahdi Moradi Marjaneh, Luize G. Lima, Kristine M. Hillman, Susanne Kaufmann, Natasha Tuano, Nehal Hussein, Sunyoung Ham, Pamela Mukhopadhyay, Stephen Kazakoff, Jason S. Lee, Kyriaki Michailidou, Daniel R. Barnes, Antonis C. Antoniou, Laura Fachal, Alison M. Dunning, Douglas F. Easton, Nicola Waddell, Joseph Rosenbluh, Andreas Möller, Georgia Chenevix-Trench, Juliet D. French, Stacey L. Edwards
Jun 06, 2020
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