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Results: 505
Automatic analysis (aa)
Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J Mitchell, Conor J Wild, Tibor Auer, Annika C Linke, Jonathan E Peelle
Jun 26, 2018
Recent years have seen neuroimaging data sets becoming richer, with larger cohorts of participants, a greater variety of acquisition techniques, and increasingly complex analyses. These advances have made data analysis pipelines...
Drawing attention to a neglected injecting‐related harm
Magdalena Harris, Rachel Brathwaite, Jennifer Scott, Gail Gilchrist, Dan Ciccarone, Vivian Hope, Catherine R. McGowan
Oct 01, 2018
Background and Aims: Chronic skin and soft tissue infections (SSTI) among people who inject drugs (PWID) can lead to AA amyloidosis: a serious, yet neglected, multi-organ disease. We aim to synthesize findings on the...
Drawing attention to a neglected injecting‐related harm
Magdalena Harris, Rachel Brathwaite, Jennifer Scott, Gail Gilchrist, Dan Ciccarone, Vivian Hope, Catherine R. McGowan
Oct 01, 2018
Background and Aims: Chronic skin and soft tissue infections (SSTI) among people who inject drugs (PWID) can lead to AA amyloidosis: a serious, yet neglected, multi-organ disease. We aim to synthesize findings on the...
Abdominal versus perineal approach for external rectal prolapse
Gianluca Pellino, Giacomo Fuschillo, Costantinos Simillis, Lucio Selvaggi, Giuseppe Signoriello, Danilo Vinci, Christos Kontovounisios, Francesco Selvaggi, Guido Sciaudone
May 09, 2022
BACKGROUND: External rectal prolapse (ERP) is a debilitating condition in which surgery plays an important role. The aim of this study was to evaluate the outcomes of abdominal approaches (AA) and perineal approaches (PA) to...
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jul 23, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people.
Nevio Taglieri, Rachele Bonfiglioli, Isabella Bon, Pietro Malosso, Andrej Corovic, Matteo Bruno, Elizabeth Le, Bianca Granozzi, Tullio Palmerini, Gabriele Ghetti, Martina Tamburello, Antonio Giulio Bruno, Francesco Saia, Jason Tarkin, James Rudd, Leonardo Calza, Stefano Fanti, Maria Carla Re, Nazzareno Galié
Jan 04, 2021
STUDY DESIGN: To compare arterial inflammation (AI) between people living with HIV (PLWH) and uninfected people as assessed by 18F-Fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET). METHODS: We prospectively...
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jul 01, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola De' Angelis, Dieter G Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B Peitzman, Gustavo P Fraga, Ronald V Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi De' Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Apr 15, 2021
BACKGROUND AND AIMS: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and...
acute appendicitis Adult Appendicitis Score Alvarado score Antibiotics Appendectomy Appendiceal abscess Appendicitis diagnosis score Appendicitis guidelines CT scan appendicitis Complicated appendicitis Consensus conference Diagnostic laparoscopy Imaging Jerusalem guidelines Laparoscopic appendectomy non-operative management Phlegmon Abdominal Pain Acute Disease Anti-Bacterial Agents Appendectomy Appendicitis Evidence-Based Medicine Humans laparoscopy Practice Guidelines as Topic
Genetically predicted plasma phospholipid arachidonic acid concentrations and 10 site-specific cancers in UK biobank and genetic consortia participants
Susanna C Larsson, Paul Carter, Mathew Vithayathil, Amy M Mason, Karl Michaëlsson, John A Baron, Stephen Burgess
Nov 03, 2020
BACKGROUND & AIMS: Arachidonic acid (AA) is metabolized by cyclooxygenases and lipoxygenases to pro-inflammatory eicosanoids, which according to experimental research modulate tumor cell proliferation, differentiation, and...
Annular versus supra-annular sizing for transcatheter aortic valve replacement in bicuspid aortic valve disease.
Jonathan R Weir-McCall, Adrian Attinger-Toller, Philipp Blanke, Gidon Y Perlman, Stephanie L Sellers, David Wood, John G Webb, Jonathon Leipsic
Sep 28, 2020
BACKGROUND: CT measurement of supra-annular area (SA) has been proposed as an alternative to annular area (AA) for sizing of trancatheter valves in biscuspid aortic valves (BAV). This study examines the reproducibility of SA and...
Aortic stenosis Bicuspid aortic valve Computer tomography Tavr Valvular disease Aged Aged 80 and over Aortic Valve aortic valve stenosis Bicuspid Aortic Valve Disease Computed Tomography Angiography Coronary Angiography Echocardiography Female Heart Valve Diseases Heart valve prosthesis Humans Male Middle Aged Multidetector Computed Tomography Predictive Value of Tests Prosthesis Design Retrospective Studies Severity of Illness Index transcatheter aortic valve replacement Treatment Outcome
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jun 06, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T R Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E Adolph
May 16, 2020
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with...
Published by: Nature Communications
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Marc Clément, Joel Chappell, Juliette Raffort, Fabien Lareyre, Marie Vandestienne, Annabel L Taylor, Alison Finigan, James Harrison, Martin R Bennett, Patrick Bruneval, Soraya Taleb, Helle F Jørgensen, Ziad Mallat
Mar 29, 2019
Objective- Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However, lineage-tracing studies are still lacking, and the...
Angiotensin II Autophagy clones Endoplasmic Reticulum Inflammation Mice Smooth muscle cells Adult Aged aortic dissection Angiotensin II Animals Aorta Aortic Aneurysm Autophagy Autophagy-Related Protein 5 Cell Lineage Cell Plasticity Cells Cultured Disease Models Animal Endoribonucleases Female Humans Male Mice 129 Strain Mice Inbred C57BL Mice Knockout ApoE Middle Aged Muscle Smooth Vascular Myocytes Smooth Muscle Phenotype Protein Serine-Threonine Kinases Signal Transduction
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai TR Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E Adolph
Apr 08, 2020
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with...
Metastatic chromophobe renal cell carcinoma treated with targeted therapies
E Colomba, G Le Teuff, T Eisen, GD Stewart, K Fife, J Larkin, A Biondo, L Pickering, A Srinivasan, H Boyle, L Derosa, CN Sternberg, F Recine, C Ralph, C Saldana, P Barthelemy, JC Bernhard, H Gurney, G Verhoest, E Vauleon, P Bigot, J Berger, C Pfister, G Gravis, J-M Rodier, S Culine, A Caty, F Rolland, F Priou, B Escudier, L Albiges
Jul 31, 2017
$\textbf{Background}$
Treatment of non–clear cell renal cell carcinoma (RCC) remains controversial despite several recent prospective studies of targeted therapies (TT). Often Vascular Endothelial growth Factor (VEGF) and...
Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid
Sarah E Bohndiek, Mikko I Kettunen, De-En Hu, Brett WC Kennedy, Joan Boren, Ferdia A Gallagher, Kevin M Brindle
Aug 09, 2017
Dynamic nuclear polarization (DNP) of (13)C-labeled metabolic substrates in vitro and their subsequent intravenous administration allow both the location of the hyperpolarized substrate and the dynamics of its subsequent...
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T. R. Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R. Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A. Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R. Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Apr 14, 2021
Abstract: The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by...
Molecular characterization of cbfβ gene and identification of new transcription variants
The CBFβ gene encodes a transcription factor that, in combination with CBFα (also called Runx, runt-related transcription factor) regulates expression of several target genes. CBFβ interacts with all Runx family members, such...
Molecular characterization of cbfβ gene and identification of new transcription variants
The CBFβ gene encodes a transcription factor that, in combination with CBFα (also called Runx, runt-related transcription factor) regulates expression of several target genes. CBFβ interacts with all Runx family members, such...
Decreased Fatty Acid Transporter FABP1 and Increased Isoprostanes and Neuroprostanes in the Human Term Placenta
Livia Belcastro, Carolina S. Ferreira, Marcelle A. Saraiva, Daniela B. Mucci, Antonio Murgia, Carla Lai, Claire Vigor, Camille Oger, Jean-Marie Galano, Gabriela D. A. Pinto, Julian L. Griffin, Alexandre G. Torres, Thierry Durand, Graham J. Burton, Fátima L. C. Sardinha, Tatiana El-Bacha
Aug 13, 2021
The rise in prevalence of obesity in women of reproductive age in developed and developing countries might propagate intergenerational cycles of detrimental effects on metabolic health. Placental lipid metabolism is disrupted by...
Design of adaptive autoreclosure schemes for 132 kV with high penetration of wind - Part I
This paper is the first of a series of publications detailing the development of an AI-based adaptive autoreclosing (AA) algorithm. In part 1, a detailed model of the Scottish 132 kV network has been constructed on a real-time...
Association of genetic variation with systolic and diastolic blood pressure among African Americans
Ervin R Fox, J Hunter Young, Yali Li, Albert W Dreisbach, Brendan J Keating, Solomon K Musani, Kiang Liu, Alanna C Morrison, Santhi Ganesh, Abdullah Kutlar, Vasan S Ramachandran, Josef F Polak, Richard R Fabsitz, Daniel L Dries, Deborah N Farlow, Susan Redline, Adebowale Adeyemo, Joel N Hirschorn, Yan V Sun, Sharon B Wyatt, Alan D Penman, Walter Palmas, Jerome I Rotter, Raymond R Townsend, Ayo P Doumatey, Bamidele O Tayo, Thomas H Mosley, Helen N Lyon, Sun J Kang, Charles N Rotimi, Richard S Cooper, Nora Franceschini, J David Curb, Lisa W Martin, Charles B Eaton, Sharon LR Kardia, Herman A Taylor, Mark J Caulfield, Georg B Ehret, Toby Johnson, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Aravinda Chakravarti, Xiaofeng Zhu, Daniel Levy
Sep 06, 2019
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic...
Contribution of cod liver oil-related nutrients (vitamins A, D, E and eicosapentaenoic acid and docosahexaenoic acid) to daily nutrient intake and their associations with plasma concentrations in the EPIC-Norfolk cohort.
Biomarkers cohort study dietary assessment Dietary Supplements total nutrient exposure Adult Aged Cod Liver Oil Cohort Studies Diet Dietary Supplements Docosahexaenoic Acids Eating Eicosapentaenoic Acid Europe Female Humans Male Middle Aged Nutrition Surveys Prospective Studies United Kingdom Vitamin A vitamin D Vitamin E Vitamins
Decreased Fatty Acid Transporter FABP1 and Increased Isoprostanes and Neuroprostanes in the Human Term Placenta
Livia Belcastro, Carolina S Ferreira, Marcelle A Saraiva, Daniela B Mucci, Antonio Murgia, Carla Lai, Claire Vigor, Camille Oger, Jean-Marie Galano, Gabriela DA Pinto, Julian L Griffin, Alexandre G Torres, Thierry Durand, Graham J Burton, Fátima LC Sardinha, Tatiana El-Bacha
Oct 27, 2021
The rise in prevalence of obesity in women of reproductive age in developed and developing countries might propagate intergenerational cycles of detrimental effects on metabolic health. Placental lipid metabolism is disrupted by...
Arachidonic Acid docosahexaenoic acid fatty acid transporter proteins Isoprostanes isoprostanoids Lipid Metabolism maternal pre-gestational obesity neuroprostanes Placenta Adult Birth Weight Fatty Acid-Binding Proteins Female Humans Inflammation Isoprostanes Lipid Metabolism Maternal Nutritional Physiological Phenomena Neuroprostanes obesity Maternal Placenta Pregnancy
Assessing the sources of reionization
We present a detailed spectroscopic analysis of a galaxy at $z \simeq 4.88$
that is, by chance, magnified $\sim 30 \times$ by gravitational lensing. Only
three sources at $z \gtrsim 5$ are known with such high magnification....
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