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Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR.
Gottfried J Palm, Bui Khanh Chi, Paul Waack, Katrin Gronau, Dörte Becher, Dirk Albrecht, Winfried Hinrichs, Randy J Read, Haike Antelmann
May 11, 2020
Bacillus subtilis encodes redox-sensing MarR-type regulators of the OhrR and DUF24-families that sense organic hydroperoxides, diamide, quinones or aldehydes via thiol-based redox-switches. In this article, we characterize the...
Bacillus subtilis Bacterial Proteins Base Sequence Cysteine DNA-Binding Proteins Diamide Gene Expression Regulation Bacterial Models Molecular Molecular Sequence Data Nitroreductases Operator Regions Genetic Oxidation-Reduction Oxidoreductases Sodium Hypochlorite Stress Physiological Trans-Activators Transcriptional Activation
Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population.
Ranjit Manchanda, Oleg Blyuss, Faiza Gaba, Vladimir Sergeevich Gordeev, Chris Jacobs, Matthew Burnell, Carmen Gan, Rohan Taylor, Clare Turnbull, Rosa Legood, Alexey Zaikin, Antonis C Antoniou, Usha Menon, Ian Jacobs
Jun 18, 2018
BACKGROUND: BRCA carrier identification offers opportunities for early diagnoses, targeted treatment and cancer prevention. We evaluate BRCA- carrier detection rates in general and Ashkenazi Jewish (AJ) populations across...
Myosin II Controls Junction Fluctuations to Guide Epithelial Tissue Ordering.
Scott Curran, Charlotte Strandkvist, Jasper Bathmann, Marc de Gennes, Alexandre Kabla, Guillaume Salbreux, Buzz Baum
Nov 23, 2018
Under conditions of homeostasis, dynamic changes in the length of individual adherens junctions (AJs) provide epithelia with the fluidity required to maintain tissue integrity in the face of intrinsic and extrinsic forces. While...
The complexity of clinically-normal sinus-rhythm ECGs is decreased in equine athletes with a diagnosis of paroxysmal atrial fibrillation.
Vadim Alexeenko, James A Fraser, Mark Bowen, Christopher L-H Huang, Celia M Marr, Kamalan Jeevaratnam
May 24, 2020
Equine athletes have a pattern of exercise which is analogous to human athletes and the cardiovascular risks in both species are similar. Both species have a propensity for atrial fibrillation (AF), which is challenging to...
Published by: Scientific reports
The application of Lempel-Ziv and Titchener complexity analysis for equine telemetric electrocardiographic recordings.
Vadim Alexeenko, James A Fraser, Alexey Dolgoborodov, Mark Bowen, Christopher L-H Huang, Celia M Marr, Kamalan Jeevaratnam
Feb 27, 2019
Cardiac ion channel expression in the equine model - In-silico prediction utilising RNA sequencing data from mixed tissue samples.
Antoine Premont, Khalil Saadeh, Charlotte Edling, Rebecca Lewis, Celia M Marr, Kamalan Jeevaratnam
Sep 02, 2022
The Ursinus Weekly, November 6, 1922
F. Nelsen Schlegel
Jan 01, 0001
Albright conquers Ursinus in battle on Myerstown field Ursinus Woman's Club entertains senior girls Radio: a liberal education for the modern world Students give program at Ladies' Aid social Graham Marr and Valentina Crespi...
Ursinus College Collegeville Pennsylvania newspaper Football George Stibitz YMCA YWCA Schaff literary society Zwinglian literary society cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Effects of breeding history and crop management on the root architecture of wheat
N. Fradgley, G. Evans, J.M. Biernaskie, J. Cockram, E.C. Marr, A. G. Oliver, E. Ober, H. Jones
Jul 20, 2020
The complexity of clinically-normal sinus-rhythm ECGs is decreased in equine athletes with a diagnosis of paroxysmal atrial fibrillation.
Vadim Alexeenko, James A Fraser, Mark Bowen, Christopher L-H Huang, Celia M Marr, Kamalan Jeevaratnam
May 07, 2020
ECG Restitution Analysis and Machine Learning to Detect Paroxysmal Atrial Fibrillation
Ying H Huang, Vadim Alexeenko, Gary Tse, Christopher L-H Huang, Celia M Marr, Kamalan Jeevaratnam
Apr 25, 2022
Atrial fibrillation is the most frequent arrhythmia in both equine and human athletes. Currently, this condition is diagnosed via electrocardiogram (ECG) monitoring which lacks sensitivity in about half of cases when it presents...
The complexity of clinically-normal sinus-rhythm ECGs is decreased in equine athletes with a diagnosis of paroxysmal atrial fibrillation
Vadim Alexeenko, James A. Fraser, Mark Bowen, Christopher L.-H. Huang, Celia M. Marr, Kamalan Jeevaratnam
Apr 22, 2021
Abstract: Equine athletes have a pattern of exercise which is analogous to human athletes and the cardiovascular risks in both species are similar. Both species have a propensity for atrial fibrillation (AF), which is...
Analysis of a Helmholtz preconditioning problem motivated by uncertainty quantification
This paper analyses the following question: let Aj, j = 1,2, be the Galerkin matrices corresponding to finite-element discretisations of the exterior Dirichlet problem for the heterogeneous Helmholtz equations ∇⋅ (Aj∇uj) +...
Analysis of a Helmholtz preconditioning problem motivated by uncertainty quantification
This paper analyses the following question: let Aj, j = 1,2, be the Galerkin matrices corresponding to finite-element discretisations of the exterior Dirichlet problem for the heterogeneous Helmholtz equations ∇⋅ (Aj∇uj) +...
Cardiac electrophysiological adaptations in the equine athlete-Restitution analysis of electrocardiographic features.
Mengye Li, Karan R Chadda, Gareth DK Matthews, Celia M Marr, Christopher L-H Huang, Kamalan Jeevaratnam
Sep 10, 2018
Exercising horses uniquely accommodate 7-8-fold increases in heart rate (HR). The present experiments for the first time analysed the related adaptations in action potential (AP) restitution properties recorded by in vivo...
Cardiac ion channel expression in the equine model - In-silico prediction utilising RNA sequencing data from mixed tissue samples.
Antoine Premont, Khalil Saadeh, Charlotte Edling, Rebecca Lewis, Celia M Marr, Kamalan Jeevaratnam
Jul 26, 2022
The Grizzly, May 2, 2019
Courtney A DuChene, Skylar Haas, Sam Isola, Johnny Myers, Shelsea Deravil, William Wehrs, Jen Joseph, David Mendelsohn, Tom Cardozo
Jan 01, 0001
Hollywood Actor Visits Ursinus UCDC Brings Dynamic Performances to COSA Ursinus Student Makes History by Being First Student to be Accepted in Major Program COSA Features Play About Racism on Campus "Calling All Textures"...
Ursinus College Collegeville Pennsylvania newspaper Colman Domingo CoSA dance Elisa Rodriguez Angela Bey White Feather Project Bonner leaders Hair St. Andrew's Society AJ Belville Kayla Quinn softball Football baseball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Plug-and-play genetic access to drosophila cell types using exchangeable exon cassettes.
Fengqiu Diao, Holly Ironfield, Haojiang Luan, Feici Diao, William C Shropshire, John Ewer, Elizabeth Marr, Christopher J Potter, Matthias Landgraf, Benjamin H White
May 11, 2015
Metabolic regulation of pluripotency and germ cell fate through α-ketoglutarate.
Julia Tischler, Wolfram H Gruhn, John Reid, Edward Allgeyer, Florian Buettner, Carsten Marr, Fabian Theis, Ben D Simons, Lorenz Wernisch, M Azim Surani
Nov 16, 2018
cell state transitions Germ Cells metabolism pseudotime analysis single‐cell analysis Animals Cell Differentiation Cells Cultured Embryo Mammalian Embryonic Stem Cells Epigenesis Genetic Female Gene Expression Regulation Developmental Germ Cells Ketoglutaric Acids Male Metabolic Networks and Pathways Mice Mice Inbred C57BL Mice Transgenic Pluripotent Stem Cells
Glucocorticoid maturation of mitochondrial respiratory capacity in skeletal muscle before birth.
In adults, glucocorticoids act to match the supply and demand for energy during physiological challenges, partly through actions on tissue mitochondrial oxidative phosphorylation (OXPHOS) capacity. However, little is known about...
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