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Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population.
Ranjit Manchanda, Oleg Blyuss, Faiza Gaba, Vladimir Sergeevich Gordeev, Chris Jacobs, Matthew Burnell, Carmen Gan, Rohan Taylor, Clare Turnbull, Rosa Legood, Alexey Zaikin, Antonis C Antoniou, Usha Menon, Ian Jacobs
Jun 18, 2018
BACKGROUND: BRCA carrier identification offers opportunities for early diagnoses, targeted treatment and cancer prevention. We evaluate BRCA- carrier detection rates in general and Ashkenazi Jewish (AJ) populations across...
Myosin II Controls Junction Fluctuations to Guide Epithelial Tissue Ordering.
Scott Curran, Charlotte Strandkvist, Jasper Bathmann, Marc de Gennes, Alexandre Kabla, Guillaume Salbreux, Buzz Baum
Nov 23, 2018
Under conditions of homeostasis, dynamic changes in the length of individual adherens junctions (AJs) provide epithelia with the fluidity required to maintain tissue integrity in the face of intrinsic and extrinsic forces. While...
Benign preparation of aqueous core poly lactic-co-glycolic acid (PLGA) microcapsules.
Poly lactic-co-glycolic acid (PLGA) has attracted considerable attention as a polymer for drug delivery carriers. However, the hydrophobic property of PLGA often leads to the use of harmful organic solvents and poor...
Film deposition and consolidation during thin glove coagulant dipping
In this article, we examine the rate of film build-up and the evolution of polymer volume fraction in coagulant dipped films. The results are for nitrile and natural rubber compounds. We describe a model for the build-up of a...
Silver-Coated Colloidosomes as Carriers for an Anticancer Drug.
Small drug molecules are widely developed and used in the pharmaceutical industry. In the past few years, loading and delivering such molecules using polymer-shell colloidosomes has attracted interest. Traditional polymer...
Sandwich layering in binary nanoparticle films and effect of size ratio on stratification behavior.
HYPOTHESIS: Stratification or self-segregation of multicomponent particle mixtures during drying is an important phenomenon to understand for the development of single-step deposition processes for complex coatings. We...
Pattern formation in drying blood drops.
Patterns in dried droplets are commonly observed as rings left after spills of dirty water or coffee have evaporated. Patterns are also seen in dried blood droplets and the patterns have been shown to differ from patients...
Blood coffee ring Diagnostics droplet drying drying Blood Physiological Phenomena Blood Proteins Desiccation Dried Blood Spot Testing Erythrocytes GLASS Humans hydrodynamics In Vitro Techniques Mathematical Concepts Models Biological Point-of-care testing Surface Properties Surface Tension suspensions wettability
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