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Micromechanics of soft materials using microfluidics
Abstract
Micron-scale soft materials are finding a wide range of applications in bioengineering and molecular medicine, while also increasingly emerging...
Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Stephen W Scally, Brandon McLeod, Alexandre Bosch, Kazutoyo Miura, Qi Liang, Sean Carroll, Sini Reponen, Ngan Nguyen, Eldar Giladi, Sebastian Rämisch, Vidadi Yusibov, Allan Bradley, Franck Lemiale, William R Schief, Daniel Emerling, Paul Kellam, C Richter King, Jean-Philippe Julien
Oct 14, 2020
The Plasmodium falciparum Pfs25 protein (Pfs25) is a leading malaria transmission-blocking vaccine antigen. Pfs25 vaccination is intended to elicit antibodies that inhibit parasite development when ingested by Anopheles...
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
David Oyen, Jonathan L Torres, Phillip C Aoto, Yevel Flores-Garcia, Špela Binter, Tossapol Pholcharee, Sean Carroll, Sini Reponen, Rachael Wash, Qi Liang, Franck Lemiale, Emily Locke, Allan Bradley, C Richter King, Daniel Emerling, Paul Kellam, Fidel Zavala, Andrew B Ward, Ian A Wilson
Apr 20, 2020
Lasting protection has long been a goal for malaria vaccines. The major surface antigen on Plasmodium falciparum sporozoites, the circumsporozoite protein (PfCSP), has been an attractive target for vaccine development and most...
Biodynamic modelling of seated human subjects exposed to uncouples vertical and fore-and-aft whole-body vibration
In this article, the biodynamic responses of seated human subjects (SHS) exposed to whole-body vibration (WBV) in both vertical and fore-and-aft directions are modelled. The mathematical model can be used to obtain a better...
Biodynamic modelling of seated human subjects exposed to uncouples vertical and fore-and-aft whole-body vibration
In this article, the biodynamic responses of seated human subjects (SHS) exposed to whole-body vibration (WBV) in both vertical and fore-and-aft directions are modelled. The mathematical model can be used to obtain a better...