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Results: 6054
Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution.
Tobias Messmer, Ferdinand von Meyenn, Aurora Savino, Fátima Santos, Hisham Mohammed, Aaron Tin Long Lun, John C Marioni, Wolf Reik
Mar 19, 2019
Conventional human embryonic stem cells are considered to be primed pluripotent but can be induced to enter a naive state. However, the transcriptional features associated with naive and primed pluripotency are still not fully...
Interview with Jean Ishbel Long Dowty
Jean Long Dowty
Jan 01, 0001
Interview with Jean Ishbel Long Dowty, mother of 2007 South Carolina Mother of the Year, Judith Dowty Pittard.
Published by: Winthrop University
Finite element analysis of the microstructure of AlN-TiN composites
Finite element modelling (FEM) is performed on AlN-TiN composites. The structure-property relationships are studied for 5 and 10vol.% TiN composites in view of thermal and thermo-mechanical properties. Thermal stresses are...
Scater
MOTIVATION: Single-cell RNA sequencing (scRNA-seq) is increasingly used to study gene expression at the level of individual cells. However, preparing raw sequence data for further analysis is not a straightforward process....
beachmat
Biological experiments involving genomics or other high-throughput assays typically yield a data matrix that can be explored and analyzed using the R programming language with packages from the Bioconductor project. Improvements...
Aaron Eichelberger Named to the 2013 Class of Newman Civic Fellows
Winthrop University
Jan 01, 0001
Aaron Eichelberger is a junior economics major form Columbia, S.C. After graduation, he plans to pursue a master's degree in urban development.
Published by: Winthrop University
Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.
Large-scale single-cell RNA sequencing (scRNA-seq) data sets that are produced in different laboratories and at different times contain batch effects that may compromise the integration and interpretation of the data. Existing...
Finite element analysis of the microstructure of AlN-TiN composites
Finite element modelling (FEM) is performed on AlN-TiN composites. The structure-property relationships are studied for 5 and 10vol.% TiN composites in view of thermal and thermo-mechanical properties. Thermal stresses are...
A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor.
Single-cell RNA sequencing (scRNA-seq) is widely used to profile the transcriptome of individual cells. This provides biological resolution that cannot be matched by bulk RNA sequencing, at the cost of increased technical noise...
Cellulose Nanocrystal-Templated Tin Dioxide Thin Films for Gas Sensing.
Alesja Ivanova, Bruno Frka-Petesic, Andrej Paul, Thorsten Wagner, Askhat N Jumabekov, Yury Vilk, Johannes Weber, Jörn Schmedt Auf der Günne, Silvia Vignolini, Michael Tiemann, Dina Fattakhova-Rohlfing, Thomas Bein
Jan 15, 2020
Porous tin dioxide is an important low-cost semiconductor applied in electronics, gas sensors, and biosensors. Here, we present a versatile template-assisted synthesis of nanostructured tin dioxide thin films using cellulose...
Detection and removal of barcode swapping in single-cell RNA-seq data.
Barcode swapping results in the mislabelling of sequencing reads between multiplexed samples on patterned flow-cell Illumina sequencing machines. This may compromise the validity of numerous genomic assays; however, the severity...
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division.
Lovorka Stojic, Aaron T L Lun, Patrice Mascalchi, Christina Ernst, Aisling M Redmond, Jasmin Mangei, Alexis R Barr, Vicky Bousgouni, Chris Bakal, John C Marioni, Duncan T Odom, Fanni Gergely
May 17, 2020
Genome stability relies on proper coordination of mitosis and cytokinesis, where dynamic microtubules capture and faithfully segregate chromosomes into daughter cells. With a high-content RNAi imaging screen targeting more than...
Published by: Nature Communications
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division
Lovorka Stojic, Aaron T. L. Lun, Patrice Mascalchi, Christina Ernst, Aisling M. Redmond, Jasmin Mangei, Alexis R. Barr, Vicky Bousgouni, Chris Bakal, John C. Marioni, Duncan T. Odom, Fanni Gergely
Apr 15, 2021
Abstract: Genome stability relies on proper coordination of mitosis and cytokinesis, where dynamic microtubules capture and faithfully segregate chromosomes into daughter cells. With a high-content RNAi imaging screen targeting...
Assessing the reliability of spike-in normalization for analyses of single-cell RNA sequencing data.
Aaron TL Lun, Fernando J Calero-Nieto, Liora Haim-Vilmovsky, Berthold Göttgens, John C Marioni
Apr 11, 2018
Tin(IV) chalcogenide complexes
A family of tin(IV) bis(hexamethylsilylamide) complexes 2–9 have been synthesized by reaction of [Sn{N(SiMe3)2}2] (1) with the diphenyl dichalcogenanes...
Tin(IV) chalcogenide complexes
A family of tin(IV) bis(hexamethylsilylamide) complexes 2–9 have been synthesized by reaction of [Sn{N(SiMe3)2}2] (1) with the diphenyl dichalcogenanes...
T cell cytolytic capacity is independent of initial stimulation strength.
Arianne C Richard, Aaron TL Lun, Winnie WY Lau, Berthold Göttgens, John C Marioni, Gillian M Griffiths
Sep 08, 2018
How cells respond to myriad stimuli with finite signaling machinery is central to immunology. In naive T cells, the inherent effect of ligand strength on activation pathways and endpoints has remained controversial, confounded...
Tin(II) Ureide Complexes
Thomas Wildsmith, James D. Parish, Ibbi Y. Ahmet, Kieran C. Molloy, Michael S. Hill, Andrew L. Johnson
Nov 15, 2021
In an attempt to tailor precursors for application in the deposition of phase pure SnO, we have evaluated a series of tin (1-6) ureide complexes. The complexes were successfully synthesized by employing...
Palladium-tin catalysts for the direct synthesis of H2O2 with high selectivity
Simon J Freakley, Qian He, Jonathan H Harrhy, Li Lu, David A Crole, David J Morgan, Edwin N Ntainjua, Jennifer K Edwards, Albert F Carley, Albina Y Borisevich, Christopher J. Kiely, Graham J. Hutchings
Feb 26, 2016
The direct synthesis of hydrogen peroxide (H2O2) from H2 and O2 represents a potentially atom-efficient alternative to the current industrial indirect process. We show that the...
Tin(II) Ureide Complexes
Thomas Wildsmith, James D. Parish, Ibbi Y. Ahmet, Kieran C. Molloy, Michael S. Hill, Andrew L. Johnson
Nov 15, 2021
In an attempt to tailor precursors for application in the deposition of phase pure SnO, we have evaluated a series of tin (1-6) ureide complexes. The complexes were successfully synthesized by employing...
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division.
Lovorka Stojic, Aaron TL Lun, Patrice Mascalchi, Christina Ernst, Aisling M Redmond, Jasmin Mangei, Alexis R Barr, Vicky Bousgouni, Chris Bakal, John C Marioni, Duncan T Odom, Fanni Gergely
Feb 11, 2020
Genome stability relies on proper coordination of mitosis and cytokinesis, where dynamic microtubules capture and faithfully segregate chromosomes into daughter cells. With a high-content RNAi imaging screen targeting more than...
From Verbal-static to Visual-dynamic
Jiuquan Han
Mar 27, 2018
Starting off from Makeham’s (2003) differentiation between historical meaning and scriptural meaning, Huang’s (2011) citation of coherence theories and Xu’s (2002; 2004a; 2004b) embodimental reading by rejecting Western logos...
Published by: Cambridge Journal of China Studies
Local Structure and Dynamics in Methylammonium, Formamidinium, and Cesium Tin(II) Mixed-Halide Perovskites from 119Sn Solid-State NMR.
Dominik J Kubicki, Daniel Prochowicz, Elodie Salager, Aydar Rakhmatullin, Clare P Grey, Lyndon Emsley, Samuel D Stranks
Apr 06, 2020
Organic-inorganic tin(II) halide perovskites have emerged as promising alternatives to lead halide perovskites in optoelectronic applications. While they suffer from considerably poorer performance and stability in comparison to...
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