Search

Results: 118
Possible Impacts of Climate Changes on Freshwater in Coastal Aquifers
Groundwater resources in coastal aquifers constitute a main source of freshwater in many regions around the globe. This is typically true in arid and semi-arid regions where rainfall is scarce and infrequent and the surface...
Possible Impacts of Climate Changes on Freshwater in Coastal Aquifers
Groundwater resources in coastal aquifers constitute a main source of freshwater in many regions around the globe. This is typically true in arid and semi-arid regions where rainfall is scarce and infrequent and the surface...
Recent molecularly imprinted polymers applications in bioanalysis.
Molecular imprinted polymers (MIPs) as extraordinary compounds with unique features have presented a wide range of applications and benefits to researchers. In particular when used as a sorbent in sample preparation methods for...
Published by:
Germ cell specification and pluripotency in mammals
Germ cells are unique cell types that generate a totipotent zygote upon fertilization, giving rise to the next generation in mammals and many other multicellular organisms. How germ cells acquire this ability has been of...
Published by:
Energy Efficiency Standards
Abdel Alshadafan
Jan 01, 2020
The decrease in the regulative power of states has generated a governance gap that has been filled by, among others, international standard-setting bodies. In these bodies, private technical experts shape the rules that govern...
On the origin of the human germline.
In mice, primordial germ cells (PGCs), the precursors of eggs and sperm, originate from pregastrulation postimplantation embryos. By contrast, the origin of human PGCs (hPGCs) has been less clear and has been difficult to study...
Published by:
The unfolding body plan of primate embryos in culture.
Improved culture of non-human primate embryos reveals the establishment of the crucial framework for subsequent development of bodily tissues and the germline in fetuses, bringing us closer to comprehending the elusive...
Published by:
Recombination and Excision: DNA Repair Proteins in Prokaryotic Host-Virus Conflicts
Amer Azim Hossain
Jan 01, 0001
Bacteriophages, or simply phages, are viruses that infect bacteria. They are the most abundant biological entity on our planet and outnumber bacteria 10:1 in the ocean. In response to this threat, bacteria have evolved a diverse...
Published by: Rockefeller University
In retrospect
M Azim Surani
Nov 27, 2019
Pluripotent cells have the potential to differentiate into any cell type in the body. Their isolation and propagation from mouse embryos was pivotal for advances in understanding human development and disease.
Published by:
Conserved features of non-primate bilaminar disc embryos and the germline.
Post-implantation embryo development commences with a bilaminar disc in most mammals, including humans. Whereas access to early human embryos is limited and subject to greater ethical scrutiny, studies on non-primate embryos...
Published by:
Batched Bayesian Optimization for Drug Design in Noisy Environments.
The early stages of the drug design process involve identifying compounds with suitable bioactivities via noisy assays. As databases of possible drugs are often very large, assays can only be performed on a subset of the...
Published by:
A simple spatial extension to the extended connectivity interaction features for binding affinity prediction.
The representation of the protein-ligand complexes used in building machine learning models play an important role in the accuracy of binding affinity prediction. The Extended Connectivity Interaction Features (ECIF) is one such...
Published by:
Specification and epigenetic programming of the human germ line.
Primordial germ cells (PGCs), the precursors of sperm and eggs, are established in perigastrulation-stage embryos in mammals. Signals from extra-embryonic tissues induce a unique gene regulatory network in germline-competent...
Published by:
Batched Bayesian Optimization for Drug Design in Noisy Environments.
The early stages of the drug design process involve identifying compounds with suitable bioactivities via noisy assays. As databases of possible drugs are often very large, assays can only be performed on a subset of the...
Published by:
Developmental Competence for Primordial Germ Cell Fate.
During mammalian embryonic development, the trophectoderm and primitive endoderm give rise to extraembryonic tissues, while the epiblast differentiates into all somatic lineages and the germline. Remarkably, only a few classes...
Published by:

|<

<

1

2

3

4

5

>

>|