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Assessing Sox2 Expression in the Spinal Cord of Ambystoma mexicanum During Single and Multiple Regenerations
Adam G Dykie
Jan 01, 0001
A major participant in neural regeneration is Sox2, expressed in neural stem cells, which differentiate into neurons and neuroglia, contributing to central nervous system restoration. The axolotl, Ambystoma mexicanum, exhibits...
Published by: Ursinus College
Assessing Sox2 Expression in the Spinal Cord of Ambystoma mexicanum During Single and Multiple Regeneration Periods
Adam G Dykie
Jan 01, 0001
A major participant in neural regeneration is the transcription factor Sox2. It is expressed in neural stem cells, likely contributing to central nervous system restoration. The axolotl, Ambystoma mexicanum, exhibits extensive...
Published by: Ursinus College
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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THE CONCISE GUIDE TO PHARMACOLOGY 2019/20
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Studies of G Protein-Coupled Receptor Stability and Dimerization Using Novel Fluorescence and Crosslinking Approaches
Adam Knepp
Jan 01, 0001
G protein-coupled receptors (GPCRs) comprise a large family of related seventransmembrane- helical membrane proteins that bind to specific extracellular ligands, such as hormones or neuromodulators. The active receptor-ligand...
Published by: Rockefeller University
Evaluating the Evidence for Enclothed Cognition

Enclothed cognition refers to the systematic influence that clothes can have on the wearer’s feelings, thoughts, and behaviors through their symbolic meaning. It has attracted considerable academic and nonacademic interest...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

Published by:
Evaluating the Evidence for Enclothed Cognition

Enclothed cognition refers to the systematic influence that clothes can have on the wearer’s feelings, thoughts, and behaviors through their symbolic meaning. It has attracted considerable academic and nonacademic interest...

Published by:

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