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Huntington's Disease
Huntington's disease is a late-onset neurodegenerative disease caused by a CAG trinucleotide repeat in the gene encoding the huntingtin protein. Despite its well-defined genetic origin, the molecular and cellular mechanisms...
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Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation.
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer's disease (AD). The use of primary microglial cell cultures has proved to be a valuable...
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Attitudes of Costa Rican individuals towards donation of personal genetic data for research
Aim: We explore attitudes from the public in Costa Rica regarding willingness to donate DNA data for research. Materials & methods: A total of 224 Costa Rican individuals answered the anonymous online survey ‘Your DNA, Your...
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Attitudes of Costa Rican individuals towards donation of personal genetic data for research
Aim: We explore attitudes from the public in Costa Rica regarding willingness to donate DNA data for research. Materials & methods: A total of 224 Costa Rican individuals answered the anonymous online survey ‘Your DNA, Your...
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Active Blended Learning
This chapter focuses on the joint implementation of blended learning and active learning. The authors analysed 152 institutional websites containing definitions of these concepts. Blended learning is commonly, though arguably...
Black Imagination: The World and Me
Livia M Nocito
Jan 01, 0001
This is a presentation regarding black imagination as a tool for reclaiming agency out of hardship or hatred. It is focused on two poems: "Malcolm" by Sonia Sanchez and "The Moongazer Speaks on Longing" by Saida Agostini and how...
Published by: Ursinus College
Lead-Free Polycrystalline Ferroelectric Nanowires with Enhanced Curie Temperature
Ferroelectrics are important technological materials with wide-ranging applications in electronics, communication, health, and energy. While lead-based ferroelectrics have remained the predominant mainstay of industry for...
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Design Thinking and Compliance as Drivers for Decision Support System Adoption in Agriculture
To respond to increasing demands for good agricultural practices (GAP) and food safety, governments globally are introducing stringent regulations to govern agricultural compliance that affect production, storage, and sales...
COVID-19 Mitigation Measures and Their Impact on Subjective Wellbeing
This study assesses the actual magnitude and scope of the impacts of the COVID-19 mitigation measures at the individual level, with special interest in subjective well-being (SWB), its relevance and how these negative effects...
Neural Mechanisms that Control an Innate Foraging Behavior in Caenorhabditis Elegans
Alejandro Lopez-Cruz
Jan 01, 0001
The ability to efficiently locate food is critical for survival. Thus, animals modify their foraging patterns based on recent experience and current conditions to increase their likelihood of finding food. One highly conserved...
Published by: Rockefeller University
On the Interactions of Augmin with Microtubules and the Mechanics of the Cross-Linker PRC1
Alejandro Dottore
Jan 01, 0001
Cell division in eukaryotes requires the assembly and maintenance of a structure, the bipolar spindle, self-organized from microtubules and their associated proteins. A multitude of components have been identified to be involved...
Published by: Rockefeller University
The infrastructures of internal colonialism:
This article explores the relation between infrastructures, labour and internal colonialism in Lerma, Mexico. Drawing on archival and ethnographic research of two hydraulic projects there, the article argues that infrastructures...
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The infrastructures of internal colonialism:
This article explores the relation between infrastructures, labour and internal colonialism in Lerma, Mexico. Drawing on archival and ethnographic research of two hydraulic projects there, the article argues that infrastructures...
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