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Results: 235
Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.
David Thybert, Maša Roller, Fábio CP Navarro, Ian Fiddes, Ian Streeter, Christine Feig, David Martin-Galvez, Mikhail Kolmogorov, Václav Janoušek, Wasiu Akanni, Bronwen Aken, Sarah Aldridge, Varshith Chakrapani, William Chow, Laura Clarke, Carla Cummins, Anthony Doran, Matthew Dunn, Leo Goodstadt, Kerstin Howe, Matthew Howell, Ambre-Aurore Josselin, Robert C Karn, Christina M Laukaitis, Lilue Jingtao, Fergal Martin, Matthieu Muffato, Stefanie Nachtweide, Michael A Quail, Cristina Sisu, Mario Stanke, Klara Stefflova, Cock Van Oosterhout, Frederic Veyrunes, Ben Ward, Fengtang Yang, Golbahar Yazdanifar, Amonida Zadissa, David J Adams, Alvis Brazma, Mark Gerstein, Benedict Paten, Son Pham, Thomas M Keane, Duncan T Odom, Paul Flicek
Sep 08, 2018
Understanding the mechanisms driving lineage-specific evolution in both primates and rodents has been hindered by the lack of sister clades with a similar phylogenetic structure having high-quality genome assemblies. Here, we...
Using the <i>Mus musculus</i> hybrid zone to assess covariation and genetic architecture of limb bone lengths
Two subspecies of the house mouse, Mus musculus domesticus and Mus musculus musculus, meet in a narrow contact zone across Europe. Mice in the hybrid zone are highly admixed, representing the full range of mixed ancestry from...
Using the <i>Mus musculus</i> hybrid zone to assess covariation and genetic architecture of limb bone lengths
Two subspecies of the house mouse, Mus musculus domesticus and Mus musculus musculus, meet in a narrow contact zone across Europe. Mice in the hybrid zone are highly admixed, representing the full range of mixed ancestry from...
Measuring Ex Vivo Muscle Contraction Forces in Mus musculus
Oniel Salik
Jan 01, 0001
Skeletal muscle injuries commonly occur during exercise and are usually in the form of a contusion or strain. These mechanical stressors lead to damaged contractile components and thus decrease the magnitude of force that the...
Published by: Ursinus College
Differences in Male and Female Ex Vivo Contractile Forces and Fatigue Post-Injury in Mus musculus
Emily Megill
Jan 01, 0001
Skeletal muscle injuries usually appear in the form of a strain or contusion as a result of exercise and lead to damaged contractile components. As a result of necrosis, these damaged components limit the total magnitude of...
Skeletal muscle Sex differences Muscle repair ex vivo Skeletal muscle fatigue Biology Musculoskeletal System
Published by: Ursinus College
Active Blended Learning
This chapter focuses on the joint implementation of blended learning and active learning. The authors analysed 152 institutional websites containing definitions of these concepts. Blended learning is commonly, though arguably...
Published by: IGI Global Scientific Publishing
Extending cognitive-behavioural theory and therapy to medically unexplained symptoms and long term conditions
Paul M. Salkovskis, James D. Gregory, Alison Sedgwick-Taylor, Julie White, Simon Opher, Sigrún Ólafsdóttir
Dec 01, 2016
Medically Unexplained Symptoms (MUS) are not only common and distressing, but also are typically poorly managed in general medical settings. Those suffering from these problems tend to incur significantly higher health costs...
Functional signatures of evolutionarily young CTCF binding sites.
BACKGROUND: The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism and...
Functional signatures of evolutionarily young CTCF binding sites
Abstract: Background: The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism...
Extending cognitive-behavioural theory and therapy to medically unexplained symptoms and long term conditions
Paul M. Salkovskis, James D. Gregory, Alison Sedgwick-Taylor, Julie White, Simon Opher, Sigrún Ólafsdóttir
Dec 01, 2016
Medically Unexplained Symptoms (MUS) are not only common and distressing, but also are typically poorly managed in general medical settings. Those suffering from these problems tend to incur significantly higher health costs...
Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees.
Wuming Gong, Alejandro A Granados, Jingyuan Hu, Matthew G Jones, Ofir Raz, Irepan Salvador-Martínez, Hanrui Zhang, Ke-Huan K Chow, Il-Youp Kwak, Renata Retkute, Alidivinas Prusokas, Augustinas Prusokas, Alex Khodaverdian, Richard Zhang, Suhas Rao, Robert Wang, Phil Rennert, Vangala G Saipradeep, Naveen Sivadasan, Aditya Rao, Thomas Joseph, Rajgopal Srinivasan, Jiajie Peng, Lu Han, Xuequn Shang, Daniel J Garry, Thomas Yu, Verena Chung, Michael Mason, Zhandong Liu, Yuanfang Guan, Nir Yosef, Jay Shendure, Maximilian J Telford, Ehud Shapiro, Michael B Elowitz, Pablo Meyer
Jun 25, 2021
The recent advent of CRISPR and other molecular tools enabled the reconstruction of cell lineages based on induced DNA mutations and promises to solve the ones of more complex organisms. To date, no lineage reconstruction...
Design Thinking and Compliance as Drivers for Decision Support System Adoption in Agriculture
To respond to increasing demands for good agricultural practices (GAP) and food safety, governments globally are introducing stringent regulations to govern agricultural compliance that affect production, storage, and sales...
Published by: IGI Global Scientific Publishing
COVID-19 Mitigation Measures and Their Impact on Subjective Wellbeing
This study assesses the actual magnitude and scope of the impacts of the COVID-19 mitigation measures at the individual level, with special interest in subjective well-being (SWB), its relevance and how these negative effects...
Published by: IGI Global Scientific Publishing
Neural Mechanisms that Control an Innate Foraging Behavior in Caenorhabditis Elegans
Alejandro Lopez-Cruz
Jan 01, 0001
The ability to efficiently locate food is critical for survival. Thus, animals modify their foraging patterns based on recent experience and current conditions to increase their likelihood of finding food. One highly conserved...
Published by: Rockefeller University
Designing services for frequent attenders to the emergency department
Frequent attendance to the emergency department (ED) is a growing public health concern. Designing services for frequent attenders poses challenges, given the heterogeneous nature of this group. This was a two-part observational...
Automated Nuclear Cartography Reveals Conserved Sperm Chromosome Territory Localization across 2 Million Years of Mouse Evolution.
Benjamin Matthew Skinner, Joanne Bacon, Claudia Cattoni Rathje, Erica Lee Larson, Emily Emiko Konishi Kopania, Jeffrey Martin Good, Nabeel Ahmed Affara, Peter James Ivor Ellis
Feb 12, 2019
Measurements of nuclear organization in asymmetric nuclei in 2D images have traditionally been manual. This is exemplified by attempts to measure chromosome position in sperm samples, typically by dividing the nucleus into...
Functional signatures of evolutionarily young CTCF binding sites
Abstract: Background: The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism...
On the Interactions of Augmin with Microtubules and the Mechanics of the Cross-Linker PRC1
Alejandro Dottore
Jan 01, 0001
Cell division in eukaryotes requires the assembly and maintenance of a structure, the bipolar spindle, self-organized from microtubules and their associated proteins. A multitude of components have been identified to be involved...
Published by: Rockefeller University
The infrastructures of internal colonialism:
Alejandro De Coss-Corzo
May 01, 2023
This article explores the relation between infrastructures, labour and internal colonialism in Lerma, Mexico. Drawing on archival and ethnographic research of two hydraulic projects there, the article argues that infrastructures...
The infrastructures of internal colonialism:
Alejandro De Coss-Corzo
May 01, 2023
This article explores the relation between infrastructures, labour and internal colonialism in Lerma, Mexico. Drawing on archival and ethnographic research of two hydraulic projects there, the article argues that infrastructures...
Genetic diversity of Phytophthora infestans in the Northern Andean region.
Brain-to-Brain Coupling in the Gamma-Band as a Marker of Shared Intentionality
Cooperation and competition are two ways of social interaction keys to life in society. Recent EEG-based hyperscanning studies reveal that cooperative and competitive interactions induce an increase in interbrain coupling....
Time Enough At Last: Identification and Analysis of Core-Clock Proteins and the Evolution of ARNT and PERIOD in the Lower Bilateria
Daniel Stanton
Jan 01, 0001
The circadian rhythm is important to all organisms and plays a key role in physiology. Although much is known about the genetic regulation of the circadian clock in Drosophila melanogaster and in Mus musculus, less is known...
Published by: Winthrop University
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