Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common and best known monogenic small vessel disease. Here, we review the clinical, neuroimaging...
Online proctoring generally refers to the practice of proctors monitoring an exam over the internet, usually through a webcam. This technology has gained relevance during the current COVID-19 pandemic, given that the social...
Historical masonry structures are vulnerable to differential settlements of the ground. This vulnerability is potentially higher for historic buildings on wooden pile foundations, which can have their bearing capacity reduced by...
Historical masonry structures are vulnerable to differential settlements of the ground. This vulnerability is potentially higher for historic buildings on wooden pile foundations, which can have their bearing capacity reduced by...
Vascular smooth muscle cells (SMCs) arise from multiple origins during development, raising the possibility that differences in embryological origins between SMCs could contribute to site-specific localization of vascular...
MOTIVATION: Diverse applications-particularly in tumour subtyping-have demonstrated the importance of integrative clustering techniques for combining information from multiple data sources. Cluster Of Clusters Analysis (COCA) is...
OBJECTIVE: To determine whether there is evidence that mass-media campaigns can be effective in reducing illicit drug consumption and the intent to consume. DESIGN: Systematic review of randomised and non-randomised studies....
One family of designs that can noticeably improve efficiency in later stages of drug development are multi-arm multi-stage (MAMS) designs. They allow several arms to be studied concurrently and gain efficiency by dropping poorly...
Requirements elicitation is a highly relevant part of the software development process. Due to the several techniques that exist to perform it, it is necessary to understand the complexity of this activity for it to be well...
Repetitive stresses and movements on the shoulder in the volleyball spike expose this joint to overuse injuries, bringing athletes to a career threatening injury. Assuming that specific spike techniques play an important role in...
BACKGROUND: Evidence for the importance of accumulating sufficient physical activity in the early years is mounting. This study aimed to determine the relationship between maternal and infant objectively measured physical...
Repetitive stresses and movements on the shoulder in the volleyball spike expose this joint to overuse injuries, bringing athletes to a career threatening injury. Assuming that specific spike techniques play an important role in...
Eosinophilic esophagitis (EoE) is a leading cause of dysphagia and food impaction in children and adults. The diagnosis relies on histological examination of esophageal mucosal biopsies and requires the presence of > 15...
α-Synuclein (αS) is an intrinsically disordered and highly dynamic protein involved in dopamine release at presynaptic terminals. The abnormal aggregation of αS as mature fibrils into intraneuronal inclusion bodies is directly...