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Results: 97
Professional duties are now considered legal duties of care within genomic medicine.
Middleton Anna, Patch Christine, Roberts Jonathan, Milne Richard, Costa Alessia, Robarts Lauren, Atutornu Jerome
Jun 22, 2020
The legal duty to protect patient confidentiality is common knowledge amongst healthcare professionals. However, what may not be widely known, is that this duty is not always absolute. In the United Kingdom, both the General...
Digital phenotyping and the (data) shadow of Alzheimer's disease.
In this paper, we examine the practice and promises of digital phenotyping. We build on work on the 'data self' to focus on a medical domain in which the value and nature of knowledge and relations with data have been played out...
Published by: Big data & society
Understanding 'passivity' in digital health through imaginaries and experiences of coronavirus disease 2019 contact tracing apps.
Growing interest is being directed to the health applications of so-called 'passive data' collected through wearables and sensors without active input by users. High promises are attached to passive data and their potential to...
Understanding 'passivity' in digital health through imaginaries and experiences of coronavirus disease 2019 contact tracing apps.
Growing interest is being directed to the health applications of so-called 'passive data' collected through wearables and sensors without active input by users. High promises are attached to passive data and their potential to...
Published by: Big data & society
Online information on face masks
OBJECTIVE: Countries have major differences in the acceptance of face mask use for the prevention of COVID-19. This work aims at studying the information online in different countries in terms of information quality and content....
Investigations by AFM of Ageing Mechanisms in PLA-Flax Fibre Composites during Garden Composting.
Alessia Melelli, Delphin Pantaloni, Eric Balnois, Olivier Arnould, Frédéric Jamme, Christophe Baley, Johnny Beaugrand, Darshil U Shah, Alain Bourmaud
Aug 26, 2021
PLA-flax non-woven composites are promising materials, coupling high performance and possible degradation at their end of life. To explore their ageing mechanisms during garden composting, microstructural investigations were...
Published by: Polymers
Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury.
Review of Terahertz Pulsed Imaging for Pharmaceutical Film Coating Analysis
Décio Alves-Lima, Jun Song, Xiaoran Li, Alessia Portieri, Yaochun Shen, J. Axel Zeitler, Hungyen Lin
Mar 10, 2020
Terahertz pulsed imaging (TPI) was introduced approximately fifteen years ago and has attracted a lot of interest in the pharmaceutical industry as a fast, non-destructive modality for quantifying film coatings on pharmaceutical...
Changing the game of time resolved X-ray diffraction on the mechanochemistry playground by downsizing.
Giulio I Lampronti, Adam AL Michalchuk, Paolo P Mazzeo, Ana Belenguer, Jeremy Sanders, Alessia Bacchi, Franziska Emmerling
Dec 15, 2021
Time resolved in situ (TRIS) monitoring has revolutionised the study of mechanochemical transformations but has been limited by available data quality. Here we report how a combination of miniaturised grinding jars together with...
Constitutive regulation of mitochondrial morphology by Aurora A kinase depends on a predicted cryptic targeting sequence at the N-terminus.
Rhys Grant, Ahmed Abdelbaki, Alessia Bertoldi, Maria P Gavilan, Jörg Mansfeld, David M Glover, Catherine Lindon
Oct 05, 2018
An inhibitor of oxidative phosphorylation exploits cancer vulnerability.
Jennifer R Molina, Yuting Sun, Marina Protopopova, Sonal Gera, Madhavi Bandi, Christopher Bristow, Timothy McAfoos, Pietro Morlacchi, Jeffrey Ackroyd, Ahmed-Noor A Agip, Gheath Al-Atrash, John Asara, Jennifer Bardenhagen, Caroline C Carrillo, Christopher Carroll, Edward Chang, Stefan Ciurea, Jason B Cross, Barbara Czako, Angela Deem, Naval Daver, John Frederick de Groot, Jian-Wen Dong, Ningping Feng, Guang Gao, Jason Gay, Mary Geck Do, Jennifer Greer, Virginia Giuliani, Jing Han, Lina Han, Verlene K Henry, Judy Hirst, Sha Huang, Yongying Jiang, Zhijun Kang, Tin Khor, Sergej Konoplev, Yu-Hsi Lin, Gang Liu, Alessia Lodi, Timothy Lofton, Helen Ma, Mikhila Mahendra, Polina Matre, Robert Mullinax, Michael Peoples, Alessia Petrocchi, Jaime Rodriguez-Canale, Riccardo Serreli, Thomas Shi, Melinda Smith, Yoko Tabe, Jay Theroff, Stefano Tiziani, Quanyun Xu, Qi Zhang, Florian Muller, Ronald A DePinho, Carlo Toniatti, Giulio F Draetta, Timothy P Heffernan, Marina Konopleva, Philip Jones, M Emilia Di Francesco, Joseph R Marszalek
Jun 21, 2018
Metabolic reprograming is an emerging hallmark of tumor biology and an actively pursued opportunity in discovery of oncology drugs. Extensive efforts have focused on therapeutic targeting of glycolysis, whereas drugging...
The Carnegie RR Lyrae Program
Tatiana Muraveva, Alessia Garofalo, Victoria Scowcroft, Gisella Clementini, Wendy L. Freedman, Barry F. Madore, Andrew J. Monson
Nov 30, 2018
We analysed 30 RR Lyrae stars (RRLs) located in the Large Magellanic Cloud (LMC) globular cluster Reticulum that were observed in the 3.6 and 4.5 $\mu$m passbands with the Infrared Array Camera (IRAC) on board of the Spitzer...
Terahertz-Based Porosity Measurement of Pharmaceutical Tablets
Prince Bawuah, Daniel Markl, Daniel Farrell, Mike Evans, Alessia Portieri, Andrew Anderson, Daniel Goodwin, Ralph Lucas, J. Axel Zeitler
Jun 06, 2020
Abstract: Porosity, one of the important quality attributes of pharmaceutical tablets, directly affects the mechanical properties, the mass transport and hence tablet disintegration, dissolution and ultimately the...
article Terahertz Spectroscopy Pharmaceutical tablet Porosity Effective medium approximation Refractive index Optical path length
Published by: Springer US
Optimal Prandial Timing of Insulin Bolus in Youths with Type 1 Diabetes
Enza Mozzillo, Roberto Franceschi, Francesca Di Candia, Alessia Ricci, Letizia Leonardi, Martina Girardi, Francesco Maria Rosanio, Maria Loredana Marcovecchio
Jan 25, 2023
The aim of this systematic review was to report the evidence on optimal prandial timing of insulin bolus in youths with type 1 diabetes. A systematic search was performed including studies published in the last 20 years...
The Carnegie RR Lyrae Program
Tatiana Muraveva, Alessia Garofalo, Victoria Scowcroft, Gisella Clementini, Wendy L. Freedman, Barry F. Madore, Andrew J. Monson
Nov 30, 2018
We analysed 30 RR Lyrae stars (RRLs) located in the Large Magellanic Cloud (LMC) globular cluster Reticulum that were observed in the 3.6 and 4.5 $\mu$m passbands with the Infrared Array Camera (IRAC) on board of the Spitzer...
Investigations by AFM of Ageing Mechanisms in PLA-Flax Fibre Composites during Garden Composting
Alessia Melelli, Delphin Pantaloni, Eric Balnois, Olivier Arnould, Frédéric Jamme, Christophe Baley, Johnny Beaugrand, Darshil U. Shah, Alain Bourmaud
Jul 28, 2021
PLA-flax non-woven composites are promising materials, coupling high performance and possible degradation at their end of life. To explore their ageing mechanisms during garden composting, microstructural investigations were...
Hydroxide Salts in the Clouds of Venus
Paul B. Rimmer, Sean Jordan, Tereza Constantinou, Peter Woitke, Oliver Shorttle, Richard Hobbs, Alessia Paschodimas
Jul 28, 2021
Abstract: The depletion of SO2 and H2O in and above the clouds of Venus (45–65 km) cannot be explained by known gas-phase chemistry and the observed composition of the atmosphere. We apply a full-atmosphere model of Venus to...
Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation.
Michèle Brocard, Valentina Iadevaia, Philipp Klein, Belinda Hall, Glenys Lewis, Jia Lu, James Burke, Margaret M Willcocks, Roy Parker, Ian G Goodfellow, Alessia Ruggieri, Nicolas Locker
Jan 31, 2020
Viral infections impose major stress on the host cell. In response, stress pathways can rapidly deploy defence mechanisms by shutting off the protein synthesis machinery and triggering the accumulation of mRNAs into stress...
Animals Caliciviridae Infections Cell Line Cytoplasmic Granules DNA Helicases Eukaryotic Initiation Factor-2 Humans Mice Mice Inbred C57BL Norovirus Poly-ADP-Ribose Binding Proteins Protein Biosynthesis RAW 264.7 Cells RNA RNA Helicases RNA Recognition Motif Proteins Signal Transduction Virus Replication
Review of Terahertz Pulsed Imaging for Pharmaceutical Film Coating Analysis.
Décio Alves-Lima, Jun Song, Xiaoran Li, Alessia Portieri, Yaochun Shen, J Axel Zeitler, Hungyen Lin
May 26, 2020
Terahertz pulsed imaging (TPI) was introduced approximately fifteen years ago and has attracted a lot of interest in the pharmaceutical industry as a fast, non-destructive modality for quantifying film coatings on pharmaceutical...
Terahertz-Based Porosity Measurement of Pharmaceutical Tablets
Prince Bawuah, Daniel Markl, Daniel Farrell, Mike Evans, Alessia Portieri, Andrew Anderson, Daniel Goodwin, Ralph Lucas, J. Axel Zeitler
Jan 10, 2021
Abstract: Porosity, one of the important quality attributes of pharmaceutical tablets, directly affects the mechanical properties, the mass transport and hence tablet disintegration, dissolution and ultimately the...
article Terahertz Spectroscopy Pharmaceutical tablet Porosity Effective medium approximation Refractive index Optical path length
Published by: Springer US
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