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Results: 222
Inverse-Kinematics Proton Scattering From 42Si
Alyssa Himmelreich
Jan 01, 0001
We studied the neutron-rich isotope 42Si using inverse-kinematics proton scattering from a liquid hydrogen target at the Facility of Rare Isotope Beams at Michigan State University. We utilized a supercomputer to run multiple...
Published by: Ursinus College
Of mice and mental health
The science of mental life is critical for understanding both how we function, and impairments in our functioning. However, understanding the causal mechanisms underlying mental health disorders and developing new treatments are...
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Holcombes Establish Education Scholarship
Winthrop University
Jan 01, 0001
Betty and Milton Holcombe have established a $50,000 endowment to benefit education majors from Bamberg, S.C. Betty Holcombe created the scholarship in honor of her college roommate, Elizabeth Carter Steedly.
Published by: Winthrop University
Holcombe Gift to Support Alumni Center at Winthrop University
Winthrop University
Jan 01, 0001
Until such time as the new Morgan-Holcombe Alumni Center is built, Winthrop University will dedicate its current Office of Alumni Relations as "The Milton W. and Betty Morgan Holcombe Alumni Center." Mrs. Holcombe noted that she...
Published by: Winthrop University
Retrieval-Extinction and Relapse Prevention
Addicted individuals are highly susceptible to relapse when exposed to drug-associated conditioned stimuli (CSs; "drug cues") even after extensive periods of abstinence. Until recently, these maladaptive emotional drug memories...
Fear not
Amy L Milton
Jan 12, 2020
Fear is a highly adaptive emotion that has evolved to promote survival and reproductive fitness. However, maladaptive expression of fear can lead to debilitating stressor-related and anxiety disorders such as post-traumatic...
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To catch a memory through covert ops.
Amy L Milton
Mar 17, 2021
Disrupting reconsolidation of the maladaptive memories underlying PTSD could be transformative for treatment. However, patients cannot undergo the direct re-exposure to trauma-cues used to induce reconsolidation in animal...
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Checking responses of goal- and sign-trackers are differentially affected by threat in a rodent analog of obsessive-compulsive disorder.
In obsessive-compulsive disorder (OCD), functional behaviors such as checking that a door is locked become dysfunctional, maladaptive, and debilitating. However, it is currently unknown how aversive and appetitive motivations...
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Synthesis and Testing of an Aldehyde-Based Fluorogenic Probe for Chlorite Detection
Alyssa St. Jean
Jan 01, 0001
Chlorite is often present in water as a byproduct of the water purification process. Concentrations of chlorite above the allowed limit can cause damage to red blood cells and is therefore regularly monitored in drinking water...
Published by: Ursinus College
Computational and Literature Analysis of Photoinduced Electron Transfer in Fluorophores Containing O/S/Se-Based Donors
Alyssa St. Jean
Jan 01, 0001
Fluorescent probes have continually been an important field of study and are widely used across many fields of science, including the detection of molecules in biological systems. The most common probes work through a 'turning...
Published by: Ursinus College
Neurochemical and molecular mechanisms underlying the retrieval-extinction effect.
Emma N Cahill, Amy L Milton
Jan 17, 2019
Extinction within the reconsolidation window, or 'retrieval-extinction', has received much research interest as a possible technique for targeting the reconsolidation of maladaptive memories with a behavioural intervention....
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Ursinus Magazine, February 1972
Once a Paisley, always an Ursinus Philosophy of the game Births Weddings In memoriam Class news Mabel Pew Myrin, Board member, benefactor, dies Century II Spring calendar Spiritual life conference here Soph aids ailing...
Published by: Ursinus College
Fear not
Amy L Milton
Dec 04, 2019
Fear is a highly adaptive emotion that has evolved to promote survival and reproductive fitness. However, maladaptive expression of fear can lead to debilitating stressor-related and anxiety disorders such as post-traumatic...
Published by:
The neural correlates of working memory training in typically developing children.
Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10-14 years...
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Reconsolidation blockade for the treatment of addiction
Addiction is a chronic, relapsing disorder. The progression to pathological drug-seeking is thought to be driven by maladaptive learning processes which store and maintain associative memory, linking drug highs with cues and...
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