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The ubiquitin family meets the Fanconi anemia proteins.
Fanconi anaemia (FA) is a hereditary disorder characterized by bone marrow failure, developmental defects, predisposition to cancer and chromosomal abnormalities. FA is caused by biallelic mutations that inactivate genes...
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Bayesian computing with INLA
The INLA approach for approximate Bayesian inference for latent Gaussian models has been shown to give fast and accurate estimates of posterior marginals and also to be a valuable tool in practice via the R-package R-INLA. New...
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Mind the Gap
The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades...
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Metabolic rewiring in mutant Kras lung cancer.
Lung cancer is the leading cause of cancer-related death worldwide, reflecting an unfortunate combination of very high prevalence and low survival rates, as most cases are diagnosed at advanced stages when treatment efficacy is...
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COVID-19 and stroke-Understanding the relationship and adapting services. A global World Stroke Organisation perspective.
A year ago the World Stroke Organisation (WSO) highlighted the enormous global impact of the COVID-19 pandemic on stroke care. In this review, we consider a year later where we are now, what the future holds, and what the...
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KRAS Allelic Imbalance
The identification of therapeutic vulnerabilities in mutant KRAS tumors has proven difficult to achieve. Burgess and colleagues recently reported in Cell that mutant/wild-type Kras allelic dosage determines clonal fitness and...
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Information extraction in emergency management missions
Abstract: With increasing demands for autonomous agents to work alongside
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
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Normalizing and denoising protein expression data from droplet-based single cell profiling.
Multimodal single-cell profiling methods that measure protein expression with oligo-conjugated antibodies hold promise for comprehensive dissection of cellular heterogeneity, yet the resulting protein counts have substantial...
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Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease
Abstract: Alzheimer’s disease is the most common age-related neurodegenerative disorder. Familial forms of Alzheimer’s disease associated with the accumulation of a toxic form of amyloid-β (Aβ) peptides are linked to...
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Bore collapse and wave run-up on a sandy beach

Wave run-up on beaches and coastal structures is initiated and driven by collapsing incident bores, this process is often considered to define the seaward limit of the swash zone. It is hence a key feature in nearshore wave...

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Information extraction in emergency management missions
Abstract: With increasing demands for autonomous agents to work alongside
humans in emergency management response (EMR), considerations of
translations of human to machine language (and the converse) are timely....
Published by:
Monitoring individual wave characteristics in the inner surf with a 2-Dimensional laser scanner (LiDAR)
This paper presents an investigation into the use of a 2-dimensional laser scanner (LiDAR) to obtain measurements of wave processes in the inner surf and swash zones of a microtidal beach (Rousty, Camargue, France). The bed is...
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Monitoring individual wave characteristics in the inner surf with a 2-Dimensional laser scanner (LiDAR)
This paper presents an investigation into the use of a 2-dimensional laser scanner (LiDAR) to obtain measurements of wave processes in the inner surf and swash zones of a microtidal beach (Rousty, Camargue, France). The bed is...
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