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Results: 172
Promoting Social Relationships Using a Couch Cooperative Video Game
Manuel Garcia, Vanessa Rull, Shirley Gunawardana, Dylan Bias, Roseanne Chua, Jairus Cruz, Ma.Corazon Raguro, Maria Perez
Jan 01, 2022
Social relationships are a fundamental aspect of human existence. Unsurprisingly, policymakers are incessantly devising strategies that accentuate the benefits of social relationships and diminish the risks of social isolation....
Published by: IGI Global Scientific Publishing
Interferon-γ signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes.
Katherine Warre-Cornish, Leo Perfect, Roland Nagy, Rodrigo RR Duarte, Matthew J Reid, Pooja Raval, Annett Mueller, Amanda L Evans, Amalie Couch, Cédric Ghevaert, Grainne McAlonan, Eva Loth, Declan Murphy, Timothy R Powell, Anthony C Vernon, Deepak P Srivastava, Jack Price
Sep 23, 2020
Maternal immune activation increases the risk of neurodevelopmental disorders. Elevated cytokines, such as interferon-γ (IFN-γ), in offspring's brains play a central role. IFN-γ activates an antiviral cellular state, limiting...
Stacy's Couch
Carrie DuPre
Jan 01, 0001
A poem
Magazine Literary Magazine Arts Magazine art poetry prose Creative Nonfiction Photography Creative Writing Creative Writing poetry
Published by: Winthrop University
The Lantern Vol. 68, No. 2, Spring 2001
Kirsten Mascioli, Benjamin Schuler, Alyson Jones, Sarah Napolitan, Corey Taylor, Padcha Tuntha-Obas, John Ramsey, Lori Kruk, Syreeta Dixon, Melanie Scriptunas, Thomas Lipschultz, Jeffrey Church, Daniel Gallagher, Mike Keeper, Monica Stahl, Ani Broderick, Christine Spera, Jason Fischer, Genevieve Romeo, Rosabelle Diaz, Raquel B. Pidal, Kelly Campbell
Jan 01, 0001
Eden Ginsberg Mourning On the Cusp of Winter (Woman: as Needing to be Silver and Sharp) Descended Book Unbinding Scrawlings on the Stall My Frankenstein Jazzy Avantguardia Paper Crane A Child's Valentine ...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Radio Catchup An interactive Segment-based Radio Listen Again Service
Christian Couch
May 01, 2017
The radio landscape has changed drastically over the past decade.
With the availability of the Internet, broadcasters have introduced
listen again radio services for users to catch up on programmes that
they missed....
With the availability of the Internet, broadcasters have introduced
listen again radio services for users to catch up on programmes that
they missed....
Published by: Department of Computer Science, University of Bath
Radio Catchup An interactive Segment-based Radio Listen Again Service
Christian Couch
May 01, 2017
The radio landscape has changed drastically over the past decade.
With the availability of the Internet, broadcasters have introduced
listen again radio services for users to catch up on programmes that
they missed....
With the availability of the Internet, broadcasters have introduced
listen again radio services for users to catch up on programmes that
they missed....
Published by: Department of Computer Science, University of Bath
Horses and cows might teach us about human knees
Our comparative study of the knees of horses and cows (paraphrased as highly evolved joggers and as domesticated couch-potatoes, respectively) demonstrates significant differences in the posterior sections of bovine and equine...
Horses and cows might teach us about human knees
Our comparative study of the knees of horses and cows (paraphrased as highly evolved joggers and as domesticated couch-potatoes, respectively) demonstrates significant differences in the posterior sections of bovine and equine...
The Discovery and Validation of Biomarkers for the Diagnosis of Esophageal Squamous Dysplasia and Squamous Cell Carcinoma.
George Couch, James E Redman, Lorenz Wernisch, Richard Newton, Shalini Malhotra, Sanford M Dawsey, Pierre Lao-Sirieix, Rebecca C Fitzgerald
Apr 26, 2016
UCSF ChimeraX
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Elaine C Meng, Gregory S Couch, Tristan I Croll, John H Morris, Thomas E Ferrin
Sep 07, 2020
UCSF ChimeraX is the next‐generation interactive visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX brings (i) significant performance and graphics...
LGBTQ Emerging Adults: Their Experiences with Homelessness
Using a qualitative method, this study explored the experiences of emerging adults (ages 18-24) who are LGBTQ and homeless in the Charlotte/Mecklenburg area of North Carolina. Emerging adults who are homeless and identify as...
Published by: Winthrop University
Conformal symmetries for extremal black holes with general asymptotic scalars in STU supergravity
Abstract
We present a construction of the most general BPS black holes of STU supergravity ($$...
Female Comedy: History and Practice
Claire Hughes
Jan 01, 0001
Lights go up on a living room with no one in it. A phone begins to ring. A woman runs out of another room with a toothbrush in her mouth. She frantically searches for the phone that is ringing, which is somewhere on the couch....
Female Comedy Funny Women Research annotated bibliography Play draft Arts and Humanities Theatre and Performance Studies
Published by: Ursinus College
Conformal symmetries for extremal black holes with general asymptotic scalars in STU supergravity
Abstract
We present a construction of the most general BPS black holes of STU supergravity ($$...
Genetic variation in stromal proteins decorin and lumican with breast cancer
Linda E Kelemen, Fergus J Couch, Shahana Ahmed, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Zachary S Fredericksen, Robert A Vierkant, V Shane Pankratz, Ellen L Goode, Christopher G Scott, David N Rider, Xianshu Wang, James R Cerhan, Celine M Vachon
Jun 14, 2011
INTRODUCTION: The stroma is the supportive framework of biologic tissue in the breast, consisting of various proteins such as the proteoglycans, decorin and lumican. Altered expression of decorin and lumican is associated with...
Gene-panel sequencing and the prediction of breast-cancer risk.
Douglas F Easton, Paul DP Pharoah, Antonis C Antoniou, Marc Tischkowitz, Sean V Tavtigian, Katherine L Nathanson, Peter Devilee, Alfons Meindl, Fergus J Couch, Melissa Southey, David E Goldgar, D Gareth R Evans, Georgia Chenevix-Trench, Nazneen Rahman, Mark Robson, Susan M Domchek, William D Foulkes
Mar 08, 2016
The combination of autofluorescence endoscopy and molecular biomarkers is a novel diagnostic tool for dysplasia in Barrett's oesophagus.
Massimiliano di Pietro, David F Boerwinkel, Mohammed Kareem Shariff, Xinxue Liu, Emmanouil Telakis, Pierre Lao-Sirieix, Elaine Walker, George Couch, Leanne Mills, Tara Nuckcheddy-Grant, Susan Slininger, Maria O'Donovan, Mike Visser, Sybren L Meijer, Philip V Kaye, Lorenz Wernisch, Krish Ragunath, Jacques JGHM Bergman, Rebecca C Fitzgerald
Feb 13, 2020
OBJECTIVE: Endoscopic surveillance for Barrett's oesophagus (BO) is limited by sampling error and the subjectivity of diagnosing dysplasia. We aimed to compare a biomarker panel on minimal biopsies directed by autofluorescence...
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers
KB Kuchenbaecker, L McGuffog, D Barrowdale, A Lee, P Soucy, J Dennis, SM Domchek, M Robson, AB Spurdle, SJ Ramus, N Mavaddat, MB Terry, SL Neuhausen, RK Schmutzler, J Simard, PDP Pharoah, K Offit, FJ Couch, G Chenevix-Trench, DF Easton, AC Antoniou
Feb 10, 2017
Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk
Celine M Vachon, Christopher G Scott, Rulla M Tamimi, Deborah J Thompson, Peter A Fasching, Jennifer Stone, Melissa C Southey, Stacey Winham, Sara Lindström, Jenna Lilyquist, Graham G Giles, Roger L Milne, Robert J Macinnis, Laura Baglietto, Jingmei Li, Kamila Czene, Manjeet K Bolla, Qin Wang, Joe Dennis, Lothar Haeberle, Mikael Eriksson, Peter Kraft, Robert Luben, Nick Wareham, Janet E Olson, Aaron Norman, Eric C Polley, Gertraud Maskarinec, Loic Le Marchand, Christopher A Haiman, John L Hopper, Fergus J Couch, Douglas F Easton, Per Hall, Nilanjan Chatterjee, Montse Garcia-Closas
May 28, 2019
breast cancer risk Breast Density genetic variation polygenic risk score Risk models Adult Aged Algorithms Biomarkers Tumor Body Mass Index Breast Density Breast Neoplasms Case-Control Studies Female Humans Middle Aged Models Biological Multifactorial Inheritance Odds Ratio Polymorphism Single Nucleotide Risk Assessment Risk Factors
Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma.
Annemieke WJ Opstal-van Winden, Hugoline G de Haan, Michael Hauptmann, Marjanka K Schmidt, Annegien Broeks, Nicola S Russell, Cécile PM Janus, Augustinus DG Krol, Frederieke H van der Baan, Marie L De Bruin, Anna M van Eggermond, Joe Dennis, Hoda Anton-Culver, Christopher A Haiman, Elinor J Sawyer, Angela Cox, Peter Devilee, Maartje J Hooning, Julian Peto, Fergus J Couch, Paul Pharoah, Nick Orr, Douglas F Easton, Berthe MP Aleman, Louise C Strong, Smita Bhatia, Rosie Cooke, Leslie L Robison, Anthony J Swerdlow, Flora E van Leeuwen
Feb 20, 2019
Female Hodgkin lymphoma (HL) patients treated with chest radiotherapy (RT) have a very high risk of breast cancer. The contribution of genetic factors to this risk is unclear. We therefore examined 211 155 germline...
Adult Aged Aged 80 and over Breast Neoplasms Cancer Survivors Case-Control Studies Female Genetic Predisposition to Disease Genotype Hodgkin Disease Humans Middle Aged Neoplasms Radiation-Induced Neoplasms Second Primary Odds Ratio Polymorphism Single Nucleotide Quality Control Radiotherapy Dosage Regression Analysis risk Young Adult
The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.
Britta Weigelt, Rui Bi, Rahul Kumar, Pedro Blecua, Diana L Mandelker, Felipe C Geyer, Fresia Pareja, Paul A James, kConFab Investigators, Fergus J Couch, Diana M Eccles, Fiona Blows, Paul Pharoah, Anqi Li, Pier Selenica, Raymond S Lim, Gowtham Jayakumaran, Nic Waddell, Ronglai Shen, Larry Norton, Hannah Y Wen, Simon N Powell, Nadeem Riaz, Mark E Robson, Jorge S Reis-Filho, Georgia Chenevix-Trench
Jul 26, 2018
Alleles Phenotype Mutation ataxia-telangiectasia hormone receptors brcal protein DNA DNA Damage Genes brcal gene tp53 gene Germ-Line Mutation Loss of Heterozygosity protein p53 Recombination Genetic Genetics Neoplasms Breast Cancer Somatic mutation biopharmaceutics classification system infiltrates cell cycle checkpoint Exome datasets
Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.
Mustapha Abubakar, Jenny Chang-Claude, H Raza Ali, Nilanjan Chatterjee, Penny Coulson, Frances Daley, Fiona Blows, Javier Benitez, Roger L Milne, Hermann Brenner, Christa Stegmaier, Arto Mannermaa, Anja Rudolph, Peter Sinn, Fergus J Couch, Peter Devilee, Rob AEM Tollenaar, Caroline Seynaeve, Jonine Figueroa, Jolanta Lissowska, Stephen Hewitt, Maartje J Hooning, Antoinette Hollestelle, Renée Foekens, Linetta B Koppert, kConFab Investigators, Manjeet K Bolla, Qin Wang, Michael E Jones, Minouk J Schoemaker, Renske Keeman, Douglas F Easton, Anthony J Swerdlow, Mark E Sherman, Marjanka K Schmidt, Paul D Pharoah, Montserrat Garcia-Closas
Apr 13, 2018
Limited epidemiological evidence suggests that the etiology of hormone receptor positive (HR+) breast cancer may differ by levels of histologic grade and proliferation. We pooled risk factor and pathology data on 5,905 HR+...
Ki67 Breast Cancer EPIDEMIOLOGY grade hormone therapy nulliparity obesity Proliferation Adult Aged Biomarkers Tumor Body Mass Index Breast Neoplasms Case-Control Studies Cell Proliferation Contraceptives Oral Hormonal Female Humans Ki-67 Antigen Middle Aged Neoplasm Grading obesity Parity Receptors Estrogen Receptors Progesterone Risk Factors
Gene-environment interactions involving functional variants
M Barrdahl, A Rudolph, JL Hopper, MC Southey, A Broeks, PA Fasching, MW Beckmann, M Gago-Dominguez, JE Castelao, P Guénel, T Truong, SE Bojesen, SM Gapstur, MM Gaudet, H Brenner, V Arndt, H Brauch, U Hamann, A Mannermaa, D Lambrechts, L Jongen, D Flesch-Janys, K Thoene, FJ Couch, GG Giles, J Simard, MS Goldberg, J Figueroa, K Michailidou, MK Bolla, J Dennis, Q Wang, U Eilber, S Behrens, K Czene, P Hall, A Cox, S Cross, A Swerdlow, MJ Schoemaker, AM Dunning, R Kaaks, PDP Pharoah, M Schmidt, M Garcia-Closas, DF Easton, RL Milne, J Chang-Claude
Aug 16, 2017
A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density.
Anja Rudolph, Peter A Fasching, Sabine Behrens, Ursula Eilber, Manjeet K Bolla, Qin Wang, Deborah Thompson, Kamila Czene, Judith S Brand, Jingmei Li, Christopher Scott, V Shane Pankratz, Kathleen Brandt, Emily Hallberg, Janet E Olson, Adam Lee, Matthias W Beckmann, Arif B Ekici, Lothar Haeberle, Gertraud Maskarinec, Loic Le Marchand, Fredrick Schumacher, Roger L Milne, Julia A Knight, Carmel Apicella, Melissa C Southey, Miroslav K Kapuscinski, John L Hopper, Irene L Andrulis, Graham G Giles, Christopher A Haiman, Kay-Tee Khaw, Robert Luben, Per Hall, Paul DP Pharoah, Fergus J Couch, Douglas F Easton, Isabel dos-Santos-Silva, Celine Vachon, Jenny Chang-Claude
Sep 03, 2015
Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer.
Kirsten GM Aspros, Jodi M Carter, Tanya L Hoskin, Vera J Suman, Malayannan Subramaniam, Michael J Emch, Zhenqing Ye, Zhifu Sun, Jason P Sinnwell, Kevin J Thompson, Xiaojia Tang, Esther PB Rodman, Xiyin Wang, Adam W Nelson, Igor Chernukhin, Feda H Hamdan, Elizabeth S Bruinsma, Jason S Carroll, Martin E Fernandez-Zapico, Steven A Johnsen, Krishna R Kalari, Haojie Huang, Roberto A Leon-Ferre, Fergus J Couch, James N Ingle, Matthew P Goetz, John R Hawse
Mar 21, 2022
Triple Negative Breast Cancer (TNBC) accounts for 15-20% of all breast cancer cases, yet is responsible for a disproportionately high percentage of breast cancer mortalities. Thus, there is an urgent need to identify novel...
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