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Blockade of chemokine-induced signalling inhibits CCR5-dependent HIV infection in vitro without blocking gp120/CCR5 interaction.
BACKGROUND: Cellular infection with human immunodeficiency virus (HIV) both in vitro and in vivo requires a member of the chemokine receptor family to act as a co-receptor for viral entry. However, it is presently unclear to...
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Andrew Carnegie and the foundations of contemporary entrepreneurial philanthropy
This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, W Jason Cummings, Larry W Tjoelker, Teizo Fujita, Steven Sacks, Peter Garred, Peter Andrew, Robert B Sim, Peter J Lachmann, Russell Wallis, Nicholas Lynch, Wilhelm J Schwaeble
Aug 05, 2019
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...
Bone Marrow Lesions and Magnetic Resonance Imaging-Detected Structural Abnormalities in Patients With Midfoot Pain and Osteoarthritis
John B Arnold, Jill Halstead, Carmen Martín-Hervás, Andrew J Grainger, Anne-Maree Keenan, Catherine L Hill, Philip G Conaghan, Dennis McGonagle, Anthony C Redmond
Dec 08, 2022
OBJECTIVE: To compare magnetic resonance imaging (MRI)-detected structural abnormalities in patients with symptomatic midfoot osteoarthritis (OA), patients with persistent midfoot pain, and asymptomatic controls, and to explore...
Conrad Russell, Richard Cust, and Andrew Thrush, eds. King James VI/I and His English Parliaments. New York
David L Smith
May 08, 2019
This book is a revised and extended version of the six Trevelyan Lectures that Conrad Russell delivered at Cambridge University in the Lent Term of 1995. Between then and his death in October 2004, Russell developed the lectures...
IPR Policy Brief - Extending working life
Andrew Weyman
Mar 01, 2013
Despite recently announced rises in the minimum age at which the State Pension is claimable, many people continue to leave the labour market before their State Pension age (SPA).
Indeed, although a significant...
Indeed, although a significant...
Published by: University of Bath
IPR Policy Brief - Extending working life
Andrew Weyman
Mar 01, 2013
Despite recently announced rises in the minimum age at which the State Pension is claimable, many people continue to leave the labour market before their State Pension age (SPA).
Indeed, although a significant...
Indeed, although a significant...
Published by: University of Bath
Correction to
Jonathan M Lawton, Mariam Habib, Bingkui Ma, Roger A Brooks, Serena M Best, Andrew L Lewis, Neil Rushton, William Bonfield
Jun 11, 2018
The article "The effect of cationically modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo", written by Jonathan M. Lawton, Mariam Habib, Bingkui Ma, Roger A. Brooks...
Effectively Measuring Exercise-Related Variations in T1ρ and T2 Relaxation Times of Healthy Articular Cartilage.
Dimitri A Kessler, James W Mackay, Scott McDonald, Stephen McDonnell, Andrew J Grainger, Alexandra R Roberts, Robert L Janiczek, Martin J Graves, Joshua D Kaggie, Fiona J Gilbert
Jun 23, 2020
LGBTQ Emerging Adults: Their Experiences with Homelessness
Using a qualitative method, this study explored the experiences of emerging adults (ages 18-24) who are LGBTQ and homeless in the Charlotte/Mecklenburg area of North Carolina. Emerging adults who are homeless and identify as...
Published by: Winthrop University
"I Don't Fit in a Box; No One Does:" Intersectionality and Gay Male Identity
Using an intersectionality framework, this qualitative study explores how stigma affects identity development and how intersecting identities can compound to either foster resiliency or create health concerns for 11 men who are...
intersectionality gay identity HIV resiliency homelessness Lesbian, Gay, Bisexual, and Transgender Studies Social Work
Published by: Winthrop University
Cannabinoids, cannabis and cannabis-based medicine for pain management
Emma Fisher, R Andrew Moore, Alex Fogarty, David Finn, Nanna B. Finnerup, Ian Gilron, Simon Haroutounian, Elliot Krane, Andrew S.C. Rice, Michael Rowbotham, M Wallace, Christopher Eccleston
Jul 31, 2021
ABSTRACT: Cannabinoids, cannabis, and cannabis-based medicines (CBMs) are increasingly used to manage pain, with limited understanding of their efficacy and safety. We summarised efficacy and adverse events (AEs) of these...
Chlamydia Uses K+ Electrical Signalling to Orchestrate Host Sensing, Inter-Bacterial Communication and Differentiation.
Prokaryotic communities coordinate quorum behaviour in response to external stimuli to control fundamental processes including inter-bacterial communication. The obligate intracellular bacterial pathogen Chlamydia adopts two...
Improving IT Project Outcomes With the Deming Management Method
Introducing technological change into an organization is a difficult undertaking, so it is not unexpected that firms struggle in their pursuit to achieve the desired level of quality for IT project outcomes. The purpose of this...
Published by: IGI Global Scientific Publishing
Cannabinoids, cannabis and cannabis-based medicine for pain management
Emma Fisher, R Andrew Moore, Alex Fogarty, David Finn, Nanna B. Finnerup, Ian Gilron, Simon Haroutounian, Elliot Krane, Andrew S.C. Rice, Michael Rowbotham, M Wallace, Christopher Eccleston
Jul 31, 2021
ABSTRACT: Cannabinoids, cannabis, and cannabis-based medicines (CBMs) are increasingly used to manage pain, with limited understanding of their efficacy and safety. We summarised efficacy and adverse events (AEs) of these...
Chlamydia Uses K + Electrical Signalling to Orchestrate Host Sensing, Inter-Bacterial Communication and Differentiation
Prokaryotic communities coordinate quorum behaviour in response to external stimuli to control fundamental processes including inter-bacterial communication. The obligate intracellular bacterial pathogen Chlamydia adopts two...
Using the Value of Information to improve conservation decision making.
Friederike C Bolam, Matthew J Grainger, Kerrie L Mengersen, Gavin B Stewart, William J Sutherland, Michael C Runge, Philip JK McGowan
Dec 12, 2018
Conservation decisions are challenging, not only because they often involve difficult conflicts among outcomes that people value, but because our understanding of the natural world and our effects on it is fraught with...
Theatre Department's ''Oklahoma'' Opens This Week
Winthrop University
Jan 01, 0001
Presented by the Department of Theatre and Dance, "Oklahoma" will run Feb. 21-24 and Feb. 25. Theatre and Dance Chair Andrew Vorder Bruegge will direct the production.
Published by: Winthrop University
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