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INTRODUCTION: Rotator Cuff tears affect 15% of 60 year olds and carry a significant social and financial burden. Current operative techniques and repair adjuncts are associated with unacceptably high failure rates, stimulating...

Rotator cuff tendon Drug delivery electropinning mechanical properties scaffolds tissue engineering. Animals Drug Delivery Systems Humans Musculoskeletal System Rotator Cuff Tendons Tissue Engineering Tissue Scaffolds

We developed a three-dimensional, computational biomechanical model of a juvenile Nile crocodile (Crocodylus niloticus) pelvis and hindlimb, composed of 47 pelvic limb muscles, to investigate muscle function. We tested whether...

XROMM Anatomy archosaur biomechanics Locomotion musculoskeletal modelling Posture Alligators and Crocodiles Animals Female Hindlimb Locomotion Models Biological Muscle Skeletal Range of Motion Articular

All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...

activation bypass innate immunity opsonization post-ischemic inflammation Complement Activation Complement C2 Complement C3 Complement C4 Humans Lectins Mannose-Binding Protein-Associated Serine Proteases

The time-dependent reproduction number, R_t, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...

state-space model Kalman filter WAVES Gompertz curve covid-19 stochastic trend Humans Models Statistical Bayes Theorem Forecasting Epidemics covid-19 SARS-CoV-2

OBJECTIVE: To determine the diagnostic accuracy of different methods of blood pressure (BP) measurement compared with reference standards for the diagnosis of hypertension in patients with obesity with a large arm circumference....

obesity PRIMARY CARE Adult Aged Arm blood pressure Blood Pressure Determination Blood Pressure Monitoring Ambulatory Body Size Humans Hypertension Middle Aged obesity Sensitivity and Specificity Wrist

This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...

capital theory Carnegie entrepreneurial philanthropy Entrepreneurship field of power social networks

This paper focuses upon the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond...

capital theory Carnegie entrepreneurial philanthropy Entrepreneurship field of power social networks

BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...

Algorithms Arabidopsis Bayes Theorem Cluster Analysis Gene Expression Profiling Oligonucleotide Array Sequence Analysis Software Design Time Factors

In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...

Alphonse R. Dochez. Etiology of Scarlet Fever Lecture delivered January 17th, 1925 Posted with permission

scarlet fever scarlatina Streptococcus

The MendelianRandomization package is a software package written for the R software environment that implements methods for Mendelian randomization based on summarized data. In this manuscript, we describe functions that have...

Mendelian randomization causal inference genetic associations. Genetic epidemiology instrumental variable post-GWAS analysis summarized data

Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System Lecture delivered December 18th, 1915

lymphatic capillary cerebrospinal fluid Human embryo Heart blood vessels

Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...

Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...

Breast Cancer Cell Biology Molecular genetics Mouse models oncology Animals BRCA1 Protein BRCA2 Protein DNA Neoplasm Female Genetic Loci Genomic Instability Humans Mammary Neoplasms Animal Mice Mice Knockout Ovarian Neoplasms Ubiquitin-Protein Ligases

In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...

Abstract The ultra-faint dwarf galaxy Reticulum II (Ret II) exhibits a unique chemical evolution history, with

320 Interstellar Matter and the Local Universe

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