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Interview with Anthony DiGiorgio
Anthony Joseph DiGiorgio
Jan 01, 0001
In his February 20, 2015 interview with Daniel Lee, Anthony DiGiorgio recollects the impact Hurricane Hugo had on Winthrop University and the Rock Hill Community. DiGiorgio discusses weather reports leading up to the hurricane...
President Hurricane power outage Tillman Stewart House Trees Breazeale Hall environmental damage Oral History
Published by: Winthrop University
POMC
Pro-opiomelanocortin (POMC) is the archetypal polypeptide precursor of hormones and neuropeptides. In this review, we examine the variability in the individual peptides produced in different tissues and the impact of the...
Reminiscences of Anthony J. Campo
The Rockefeller University
Jan 01, 0001
OCCASIONAL PAPERS by the faculty and staff of The Rockefeller University are published at irregular intervals by The Rockefeller University Press, New York, N. Y. This is Occasional Paper Fifteen of which five hundred have been...
Published by: The Rockefeller University Press
Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care.
Lia Bally, Hood Thabit, Sara Hartnell, Eveline Andereggen, Yue Ruan, Malgorzata E Wilinska, Mark L Evans, Maria M Wertli, Anthony P Coll, Christoph Stettler, Roman Hovorka
Sep 20, 2018
BACKGROUND: In patients with diabetes, hospitalization can complicate the achievement of recommended glycemic targets. There is increasing evidence that a closed-loop delivery system (artificial pancreas) can improve glucose...
Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons.
Erika Harno, Charlotte Sefton, Jonathan R Wray, Tiffany-Jayne Allen, Alison Davies, Anthony P Coll, Anne White
Jun 08, 2021
Closed-loop insulin delivery in inpatients with type 2 diabetes
Hood Thabit, Sara Hartnell, Janet M Allen, Andrea Lake, Malgorzata E Wilinska, Yue Ruan, Mark L Evans, Anthony P Coll, Roman Hovorka
Nov 10, 2016
Neuroarthropathy in diabetes
Charcot neuroarthropathy is a rare but serious complication of diabetes, causing progressive destruction of the bones and joints of the foot leading to deformity, altered biomechanics and an increased risk of ulceration....
Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.
Zoi Michailidou, Anthony P Coll, Christopher J Kenyon, Nicholas M Morton, Stephen O'Rahilly, Jonathan R Seckl, Karen E Chapman
Jan 18, 2021
Proopiomelanocortin (POMC) deficiency causes severe obesity through hyperphagia of hypothalamic origin. However, low glucocorticoid levels caused by adrenal insufficiency mitigate against insulin resistance, hyperphagia and fat...
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome.
Joseph Polex-Wolf, Brian YH Lam, Rachel Larder, John Tadross, Debra Rimmington, Fàtima Bosch, Verónica Jiménez Cenzano, Eduard Ayuso, Marcella Kl Ma, Kara Rainbow, Anthony P Coll, Stephen O'Rahilly, Giles SH Yeo
Mar 20, 2018
Profound hyperphagia is a major disabling feature of Prader-Willi syndrome (PWS). Characterization of the mechanisms that underlie PWS-associated hyperphagia has been slowed by the paucity of animal models with increased food...
Fully closed-loop insulin delivery in inpatients receiving nutritional support
Charlotte K Boughton, Lia Bally, Franco Martignoni, Sara Hartnell, David Herzig, Andreas Vogt, Maria M Wertli, Malgorzata E Wilinska, Mark L Evans, Anthony P Coll, Christoph Stettler, Roman Hovorka
Feb 18, 2019
BACKGROUND: Glucose management is challenging in patients who require nutritional support in hospital. We aimed to assess whether fully closed-loop insulin delivery would improve glycaemic control compared with conventional...
Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice.
Charlotte Sefton, Erika Harno, Alison Davies, Helen Small, Tiffany-Jayne Allen, Jonathan R Wray, Catherine B Lawrence, Anthony P Coll, Anne White
Nov 29, 2016
Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is...
Fully closed-loop insulin delivery improves glucose control of inpatients with type 2 diabetes receiving hemodialysis.
Lia Bally, Philipp Gubler, Hood Thabit, Sara Hartnell, Yue Ruan, Malgorzata E Wilinska, Mark L Evans, Mariam Semmo, Bruno Vogt, Anthony P Coll, Christoph Stettler, Roman Hovorka
Mar 11, 2019
Inpatient diabetes management of those on hemodialysis poses a major challenge. In a post hoc analysis of a randomized controlled clinical trial, we compared the efficacy of fully automated closed-loop insulin delivery vs. usual...
Artificial Pancreas closed-loop insulin delivery Glucose control hemodialysis Aged Aged 80 and over Blood Glucose Diabetes mellitus Type 2 Drug Therapy Computer-Assisted Female Hospitalization Humans Hypoglycemic Agents Infusion Pumps Implantable Insulin Aspart Insulin Infusion Systems Insulin Lispro Kidney Failure Chronic Male Middle Aged Monitoring Physiologic Renal Dialysis Treatment Outcome
FTO is necessary for the induction of leptin resistance by high-fat feeding.
YC Loraine Tung, Pawan Gulati, Che-Hsiung Liu, Debra Rimmington, Rowena Dennis, Marcella Ma, Vladimir Saudek, Stephen O'Rahilly, Anthony P Coll, Giles SH Yeo
Apr 22, 2015
FTO FaT mass and Obesity related Fto GWAS Genome-wide association studies HFD high-fat diet High-fat diet Hypothalamus ICV intracerebroventricular injection Irx3 Iroquois Homeobox 3 Leptin resistance MEF Mouse embryonic fibroblasts NFкB Ob-R leptin receptor PTPs protein-tyrosine phosphatase SNPs single nucleotide polymorphisms SOCS3 SOCS3 suppressor of cytokine signalling TRIP4 Tlr4 Toll-like receptor 4 WAT white adipose tissue Y2H Yeast two-hybrid
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.
Georgina KC Dowsett, Brian YH Lam, John A Tadross, Irene Cimino, Debra Rimmington, Anthony P Coll, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, Giles SH Yeo
Apr 26, 2021
Metabolic Abnormalities of Chronic High-Dose Glucocorticoids Are Not Mediated by Hypothalamic AgRP in Male Mice.
Charlotte Sefton, Alison Davies, Tiffany-Jayne Allen, Jonathan R Wray, Rosemary Shoop, Antony Adamson, Neil Humphreys, Anthony P Coll, Anne White, Erika Harno
Feb 27, 2019
Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.
Sasha R Howard, Leonardo Guasti, Ariel Poliandri, Alessia David, Claudia P Cabrera, Michael R Barnes, Karoliina Wehkalampi, Stephen O'Rahilly, Catherine E Aiken, Anthony P Coll, Marcella Ma, Debra Rimmington, Giles SH Yeo, Leo Dunkel
Feb 05, 2018
CONTEXT: Self-limited delayed puberty (DP) is often associated with a delay in physical maturation, but although highly heritable the causal genetic factors remain elusive. Genome-wide association studies of the timing of...
Global Transcriptomic Analysis of the Arcuate Nucleus following Chronic Glucocorticoid Treatment
Jonathan R Wray, Alison Davies, Charlotte Sefton, Tiffany-Jayne Allen, Antony Adamson, Philip Chapman, Brian YH Lam, Giles SH Yeo, Anthony P Coll, Erika Harno, Anne White
May 23, 2019
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells.
Ming Yang, Tamana Darwish, Pierre Larraufie, Debra Rimmington, Irene Cimino, Deborah A Goldspink, Benjamin Jenkins, Albert Koulman, Cheryl A Brighton, Marcella Ma, Brian YH Lam, Anthony P Coll, Stephen O'Rahilly, Frank Reimann, Fiona M Gribble
Jan 06, 2021
Interview with Gwen P. Howell
Gwen P. Howell
Jan 01, 0001
Interview with Gwen P. Howell, member of the South Carolina Mothers Association.
Published by: Winthrop University
Day-to-day variability of insulin requirements in the inpatient setting
Charlotte K Boughton, Aideen Daly, Hood Thabit, Sara Hartnell, David Herzig, Andreas Vogt, Yue Ruan, Malgorzata E Wilinska, Mark L Evans, Anthony P Coll, Lia Bally, Roman Hovorka
Apr 01, 2021
continuous glucose monitoring (CGM) Diabetes Complications insulin pump therapy insulin therapy Observational study Type 2 diabetes Adult Blood Glucose Cross-Over Studies Diabetes mellitus Type 1 Diabetes mellitus Type 2 Humans Hypoglycemic Agents Inpatients Insulin Insulin Infusion Systems Retrospective Studies
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity
Irene Cimino, Debra Rimmington, Y. C. Loraine Tung, Katherine Lawler, Pierre Larraufie, Richard G. Kay, Samuel Virtue, Brian Y. H. Lam, Luca Fagnocchi, Marcella K. L. Ma, Vladimir Saudek, Ilona Zvetkova, Antonio Vidal-Puig, Giles S. H. Yeo, I. Sadaf Farooqi, J. Andrew Pospisilik, Fiona M. Gribble, Frank Reimann, Stephen O’Rahilly, Anthony P. Coll
Sep 02, 2021
Abstract: Neuronatin (Nnat) has previously been reported to be part of a network of imprinted genes downstream of the chromatin regulator Trim28. Disruption of Trim28 or of members of this network, including neuronatin, results...
Mixed Small-Molecule Matrices Improve Nanoparticle Dispersibility in Organic Semiconductor-Nanoparticle Films.
Daniel TW Toolan, Michael P Weir, Rachel C Kilbride, John E Anthony, Neil C Greenham, Richard H Friend, Akshay Rao, Oleksandr O Mykhaylyk, Richard AL Jones, Anthony J Ryan
Apr 05, 2023
Controlling the dispersibility of nanocrystalline inorganic quantum dots (QDs) within organic semiconductor (OSC):QD nanocomposite films is critical for a wide range of optoelectronic devices. This work demonstrates how small...
PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
Published by: IGI Global Scientific Publishing
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