Search
Results: 90
A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes.
Leire Pedrosa, Carles Foguet, Helena Oliveres, Iván Archilla, Marta García de Herreros, Adela Rodríguez, Antonio Postigo, Daniel Benítez-Ribas, Jordi Camps, Miriam Cuatrecasas, Antoni Castells, Aleix Prat, Timothy M Thomson, Joan Maurel, Marta Cascante
Sep 16, 2022
Dynamic condensation of linker histone C-terminal domain regulates chromatin structure.
The basic and intrinsically disordered C-terminal domain (CTD) of the linker histone (LH) is essential for chromatin compaction. However, its conformation upon nucleosome binding and its impact on chromatin organization remain...
Measuring the Dust Masses of Protoplanetary Disks in Lupus with ALMA
Abstract
Accurate disk mass measurements are necessary to constrain disk evolution and the timescale of planet formation, but such measurements are difficult to make and are very...
The Grizzly, March 26, 1996
Marc Ellman, Mark Leiser, Kristen Schumann, Joanna Doyle, Melissa Forbes, Jared Rakes, Chris Bowers, Melinda Albert, Erin Callahan, Jennifer Urban, Beatrice May, Colin Tucker, Joel Schofer, Mary Hearl, Charlie Weingroff, Kate Goddard, Hera Walker
Jan 01, 0001
Marijuana Incident Results in Dismissal of Two Students UC Professors to Participate in AIDS Ride Ryan Auch: The Gentle Giant Women's Week Opinions: Capitalism, Individualism and Responsibility; Scotland Fury Thoughts on...
Ursinus College Collegeville Pennsylvania newspaper lacrosse softball baseball Janetta Trecroce Baydallaye Kane Antoni Castells-Talens Berwyn Tavern honor code Women's Week Lynn H. Yeakel Ryan Auch Hugh Clark Paul Stern drug trafficking cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Semantic and phonological schema influence spoken word learning and overnight consolidation.
Viktória Havas, JSH Taylor, Lucía Vaquero, Ruth de Diego-Balaguer, Antoni Rodríguez-Fornells, Matthew H Davis
Jan 18, 2019
Determining Dust Properties in Protoplanetary Disks
Abstract
We present spectral energy distribution (SED) modeling of 338 disks around T Tauri stars from 11 star-forming regions, ranging from ∼0.5 to 10 Myr old. The disk masses we...
Anneliese M Rilinger, Catherine C Espaillat, Zihua Xin, Álvaro Ribas, Enrique Macías, Sarah Luettgen
Feb 13, 2023
Para-chloro-2-[18F]fluoroethyl-etomidate
Isabella Silins, Anders Sundin, Patrik Nordeman, Mahabuba Jahan, Sergio Estrada, Azita Monazzam, Mark Lubberink, Franklin Aigbirhio, Per Hellman, Gunnar Antoni
May 21, 2021
Introduction: [11C]Metomidate ([11C]MTO), the methyl ester analogue of etomidate, was developed as a positron emission tomography (PET) radiotracer for adrenocortical tumours and has also been suggested for imaging in primary...
18F-CETO Adrenal masses Adrenal tracer positron emission tomography primary aldosteronism Adrenal Cortex Adrenal Cortex Neoplasms Animals Drug Evaluation Preclinical Etomidate Fluorine Radioisotopes Humans hyperaldosteronism Macaca fascicularis Mice Positron-Emission Tomography Radiopharmaceuticals Rats Tissue Distribution
Chromosomal painting of the sandpiper (Actitis macularius) detects several fissions for the Scolopacidae family (Charadriiformes).
Melquizedec Luiz Silva Pinheiro, Cleusa Yoshiko Nagamachi, Talita Fernanda Augusto Ribas, Cristovam Guerreiro Diniz, Patricia Caroline Mary O Brien, Malcolm Andrew Ferguson-Smith, Fengtang Yang, Julio Cesar Pieczarka
Jan 22, 2021
BACKGROUND: The Scolopacidae family (Suborder Scolopaci, Charadriiformes) is composed of sandpipers and snipes; these birds are long-distance migrants that show great diversity in their behavior and habitat use. Cytogenetic...
Persistence of Multiple Paramyxoviruses in a Closed Captive Colony of Fruit Bats ( Eidolon helvum )
Louise Gibson, Maria Puig Ribas, James Kemp, Olivier Restif, Richard D. Suu-Ire, James L. N. Wood, Andrew A. Cunningham
Aug 26, 2021
Bats have been identified as the natural hosts of several emerging zoonotic viruses, including paramyxoviruses, such as Hendra and Nipah viruses, that can cause fatal disease in humans. Recently, African fruit bats with...
FOXA1 is a key determinant of estrogen receptor function and endocrine response.
Estrogen receptor-α (ER) is the key feature of most breast cancers and binding of ER to the genome correlates with expression of the Forkhead protein FOXA1 (also called HNF3α). Here we show that FOXA1 is a key determinant that...
Chromosomal painting in Charadrius collaris Vieillot, 1818 and Vanellus chilensis Molina, 1782 and an analysis of chromosomal signatures in Charadriiformes.
Melquizedec Luiz Silva Pinheiro, Cleusa Yoshiko Nagamachi, Talita Fernanda Augusto Ribas, Cristovam Guerreiro Diniz, Patricia Caroline Mary O Brien, Malcolm Andrew Ferguson-Smith, Fengtang Yang, Julio Cesar Pieczarka
Sep 10, 2022
Charadriiformes represent one of the largest orders of birds; members of this order are diverse in morphology, behavior and reproduction, making them an excellent model for studying evolution. It is accepted that the avian...
Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
Arun Mouli Kolinjivadi, Vincenzo Sannino, Anna De Antoni, Karina Zadorozhny, Mairi Kilkenny, Hervé Técher, Giorgio Baldi, Rong Shen, Alberto Ciccia, Luca Pellegrini, Lumir Krejci, Vincenzo Costanzo
Sep 03, 2019
BRCA2 DNA Replication Mre11 RAD51 Xenopus laevis fork protection Animals BRCA2 Protein Binding Sites DNA DNA Helicases DNA Polymerase I DNA Polymerase III DNA Replication DNA-Binding Proteins Endodeoxyribonucleases Exodeoxyribonucleases Female Genomic Instability Humans MRE11 Homologue Protein Male Mutation Protein Binding Rad51 Recombinase Replication Origin Saccharomyces cerevisiae Proteins Time Factors Xenopus Proteins Xenopus laevis
Chromosomal painting in Charadrius collaris Vieillot, 1818 and Vanellus chilensis Molina, 1782 and an analysis of chromosomal signatures in Charadriiformes.
Melquizedec Luiz Silva Pinheiro, Cleusa Yoshiko Nagamachi, Talita Fernanda Augusto Ribas, Cristovam Guerreiro Diniz, Patricia Caroline Mary O Brien, Malcolm Andrew Ferguson-Smith, Fengtang Yang, Julio Cesar Pieczarka
Aug 10, 2022
Charadriiformes represent one of the largest orders of birds; members of this order are diverse in morphology, behavior and reproduction, making them an excellent model for studying evolution. It is accepted that the avian...
Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection.
Margarita-Maria Panou, Emma L Prescott, Daniel L Hurdiss, Gemma Swinscoe, Michael Hollinshead, Laura G Caller, Ethan L Morgan, Louisa Carlisle, Marietta Müller, Michelle Antoni, David Kealy, Neil A Ranson, Colin M Crump, Andrew Macdonald
Sep 26, 2018
BK polyomavirus (BKPyV; hereafter referred to as BK) causes a lifelong chronic infection and is associated with debilitating disease in kidney transplant recipients. Despite its importance, aspects of the virus life cycle remain...
agnoprotein polyomavirus virus exit Animals BK Virus Cell Nucleus Chlorocebus aethiops Gene Expression Regulation Viral Nuclear Envelope Polyomavirus Infections Protein Binding Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins Transcription Genetic Vero Cells Viral Regulatory and Accessory Proteins Virion
Major milestones in translational oncology.
Tommaso A Dragani, Antoni Castells, Vathany Kulasingam, Eleftherios P Diamandis, Helena Earl, Wade T Iams, Christine M Lovly, JP Michiel Sedelaar, Jack A Schalken
Sep 29, 2016
Translational oncology represents a bridge between basic research and clinical practice in cancer medicine. Today, translational research in oncology benefits from an abundance of knowledge resulting from genome-scale studies...
Biomarkers Breast Cancer vaccines Colorectal Early Diagnosis Genetic profile Immunotherapy Individual risk Liquid biopsy Lung Mutational landscape Next generation sequencing Ovarian Prostate Tumorigenesis Biomarkers Tumor Humans Medical Oncology Molecular Targeted Therapy Translational Research Biomedical
Analysis of multiple chromosomal rearrangements in the genome of Willisornis vidua using BAC-FISH and chromosome painting on a supposed conserved karyotype.
Talita Fernanda Augusto Ribas, Julio Cesar Pieczarka, Darren K Griffin, Lucas G Kiazim, Cleusa Yoshiko Nagamachi, Patricia Caroline Mary O Brien, Malcolm Andrew Ferguson-Smith, Fengtang Yang, Alexandre Aleixo, Rebecca E O'Connor
May 10, 2021
BACKGROUND: Thamnophilidae birds are the result of a monophyletic radiation of insectivorous Passeriformes. They are a diverse group of 225 species and 45 genera and occur in lowlands and lower montane forests of Neotropics....
First-in-human evaluation of [18F]CETO
Isabella Silins, Anders Sundin, Mark Lubberink, Lleah O'Sullivan, Mark Gurnell, Franklin Aigbirhio, Morris Brown, Anders Wall, Tobias Åkerström, Sara Roslin, Per Hellman, Gunnar Antoni
Jan 05, 2023
The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen.
Shixiong Wang, Venkata S Somisetty, Baoyan Bai, Igor Chernukhin, Henri Niskanen, Minna U Kaikkonen, Meritxell Bellet, Jason S Carroll, Antoni Hurtado
Nov 30, 2020
Tamoxifen is the most prescribed selective estrogen receptor (ER) modulator in patients with ER-positive breast cancers. Tamoxifen requires the transcription factor paired box 2 protein (PAX2) to repress the transcription of...
Antineoplastic Agents Hormonal Apoptosis Breast Breast Neoplasms Cell Line Tumor Cell Proliferation Chromatin Immunoprecipitation Sequencing Drug Resistance Neoplasm Estrogens Female Gene Expression Regulation Neoplastic Humans Interferon Regulatory Factor-1 Neoplasm Recurrence Local PAX2 Transcription Factor Prognosis Promoter Regions Genetic Receptor ErbB-2 Receptors Estrogen Signal Transduction Tamoxifen Transcriptional Activation Up-Regulation
Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting.
Paloma Navarro Negredo, James R Edgar, Antoni G Wrobel, Nathan R Zaccai, Robin Antrobus, David J Owen, Margaret S Robinson
Sep 11, 2018
Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. To find acidic cluster sorting machinery, we performed a gene-trap...
Adaptor Protein Complex 1 Adaptor Protein Complex mu Subunits CRISPR-Cas Systems Clathrin-Coated Vesicles Flow Cytometry Gene Knockdown Techniques Genotype HEK293 Cells HIV-1 HeLa Cells Histocompatibility Antigens Class I Host-Pathogen Interactions Humans Models Molecular Mutation Phenotype Protein Binding Protein Interaction Domains and Motifs Protein Transport Structure-Activity Relationship Time Factors Transfection nef Gene Products Human Immunodeficiency Virus
Nicola De Franceschi, Antti Arjonen, Nadia Elkhatib, Konstantin Denessiouk, Antoni G Wrobel, Thomas A Wilson, Jeroen Pouwels, Guillaume Montagnac, David J Owen, Johanna Ivaska
Jan 08, 2016
ADHD Remote Technology study of cardiometabolic risk factors and medication adherence (ART-CARMA)
Hayley Denyer, J Antoni Ramos-Quiroga, Amos Folarin, Carolina Ramos, Petra Nemeth, Andrea Bilbow, Euan Woodward, Susannah Whitwell, Ulrich Müller-Sedgwick, Henrik Larsson, Richard JB Dobson, Jonna Kuntsi
Dec 20, 2022
BACKGROUND: Emerging evidence points at substantial comorbidity between adult attention deficit hyperactivity disorder (ADHD) and cardiometabolic diseases, but our understanding of the comorbidity and how to manage...
Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Li Ma, Perunthottathu K Umasankar, Antoni G Wrobel, Anastasia Lymar, Airlie J McCoy, Sachin S Holkar, Anupma Jha, Tirthadipa Pradhan-Sundd, Simon C Watkins, David J Owen, Linton M Traub
Jun 23, 2016
Adaptor Protein Complex 2 Adaptor Proteins Signal Transducing Amino Acid Motifs Amino Acid Sequence Animals Clathrin Clathrin-Coated Vesicles Endocytosis Fatty Acid-Binding Proteins HeLa Cells Humans Membrane Proteins Models Biological Models Molecular Protein Binding Protein Domains Protein Interaction Maps Rats Transfection
Giant barocaloric effects over a wide temperature range in superionic conductor AgI.
Araceli Aznar, Pol Lloveras, Michela Romanini, María Barrio, Josep-Lluís Tamarit, Claudio Cazorla, Daniel Errandonea, Neil D Mathur, Antoni Planes, Xavier Moya, Lluís Mañosa
Jan 25, 2018
Current interest in barocaloric effects has been stimulated by the discovery that these pressure-driven thermal changes can be giant near ferroic phase transitions in materials that display magnetic or electrical order. Here we...
|
|< |
< |
1 |