PAM-1 is a puromycin sensitive aminopeptidase responsible for cleaving amino acids from the N-terminus of unknown target proteins. In our model system, a microscopic nematode known as C. elegans, functional PAM-1 is required for...
This research is focused on part of the cell cycle that involves the first cell division, otherwise known as mitosis. Regulation of mitosis is very important as mistakes can cause problems such as uncontrolled cell division...
The puromycin-sensitive aminopeptidase, PAM-1, is crucial for polarity establishment, pseudocleavage, and symmetric division, all of which are clear signs of viable development of one cell C. elegans embryos. We have found...
In order to develop into mature organisms, fertilized embryos must go through growth, DNA replication, and cell division. These phases together make up the cell cycle, and movement through the phases is facilitated by many...
PAM-1 is a puromycin sensitive aminopeptidase responsible for cleaving the amino acid from the N-terminus of unknown target proteins. In our model system, a microscopic nematode known as C. elegans, functional PAM-1 is required...
PAM-1 is a puromycin sensitive aminopeptidase responsible for cleaving the amino acid from the N-terminus of unknown target proteins. In our model system, a microscopic nematode known as C. elegans, functional PAM-1 is required...
Abstract: We investigate a speculative short-distance force, proposed to explain discrepancies observed between measurements of certain neutral current decays of B hadrons and their Standard Model predictions. The force derives...
Abstract: We investigate a speculative short-distance force, proposed to explain discrepancies observed between measurements of certain neutral current decays of B hadrons and their Standard Model predictions. The force derives...
Abstract: We investigate a speculative short-distance force, proposed to explain discrepancies observed between measurements of certain neutral current decays of B hadrons and their Standard Model predictions. The force derives...
I investigated the relationship between two developmental proteins, PAM-1 and WEE-1.3. WEE-1.3 is an inhibitory kinase that regulates a maturation promoting complex called CDK-1, and is responsible for timely oocyte development....
Abstract: We investigate a speculative short-distance force, proposed to explain discrepancies observed between measurements of certain neutral current decays of B hadrons and their Standard Model predictions. The force derives...
Caenorhabditis elegans are microscopic worms that are a great model organism for examining genes and proteins involved in the reproductive system because of their fecundity, easy manipulation, and visible gonad. The Lyczak lab...
PURPOSE: The B-MaP-C study investigated changes to breast cancer care that were necessitated by the COVID-19 pandemic. Here we present a follow-up analysis of those patients commenced on bridging endocrine therapy (BrET), whilst...
A measurement of four branching-fraction ratios for three-body decays of $B$
mesons involving two open-charm hadrons in the final state is presented. Run 1
and Run 2 $pp$ collision data are used, recorded by the LHCb experiment...
Abstract: Measurements of CP observables in B± → D(*)K± and B± → D(*)π± decays are presented, where D(∗) indicates a neutral D or D∗ meson that is an admixture of meson and anti-meson states. Decays of the D(∗) meson to the Dπ0...
Abstract: Measurements of CP observables in B± → D(*)K± and B± → D(*)π± decays are presented, where D(∗) indicates a neutral D or D∗ meson that is an admixture of meson and anti-meson states. Decays of the D(∗) meson to the Dπ0...
Abstract: We report on the calculation of the next-to-leading order QCD corrections to the production of a tt¯ pair in association with two heavy-flavour jets. We concentrate on the di-lepton tt¯ decay channel at the LHC with s...
Abstract: A search is presented for the lepton flavour violating decay B+ → K+μ−τ+ using a sample of proton-proton collisions at centre-of-mass energies of 7, 8, and 13 TeV, collected with the LHCb detector and corresponding to...
Abstract: Measurements of CP observables in B± → DK± and B± → Dπ± decays are presented, where D represents a superposition of D0 and D¯0 states. The D meson is reconstructed in the three-body final states KS0K±π∓ and KS0K∓π±....
Abstract: A search is presented for the lepton flavour violating decay B+ → K+μ−τ+ using a sample of proton-proton collisions at centre-of-mass energies of 7, 8, and 13 TeV, collected with the LHCb detector and corresponding to...
Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that...
Abstract: A measurement of CP-violating observables is performed using the decays B± → DK± and B± → Dπ±, where the D meson is reconstructed in one of the self-conjugate three-body final states KS0π+π− and KS0K+K− (commonly...
Abstract: A structure is observed in the B±K∓ mass spectrum in a sample of proton–proton collisions at centre-of-mass energies of 7, 8, and 13 TeV, collected with the LHCb detector and corresponding to a total integrated...
Abstract: Measurements of CP observables in B± → DK± and B± → Dπ± decays are presented, where D represents a superposition of D0 and D¯0 states. The D meson is reconstructed in the three-body final states KS0K±π∓ and KS0K∓π±....