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Exploring the role of normative, financial and environmental information in promoting uptake of energy efficient technologies
The potential of normative and feedback (financial vs. environmental) information in guiding pro-environmental decision-making behaviour was explored in a 2 × 2 (plus control) choice experiment. Using the context of home...
behaviour change decision-making Energy efficient technologies Environmental behaviour Feedback frames Social Norms /dk/atira/pure/subjectarea/asjc/3200/3207 name=Social Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.
Yuteng Wu, Fabrizio Villa, Joseph Maman, Yu Heng Lau, Lina Dobnikar, Aline C Simon, Karim Labib, David R Spring, Luca Pellegrini
Apr 26, 2018
The exploitation of synthetic lethality by small-molecule targeting of pathways that maintain genomic stability is an attractive chemotherapeutic approach. The Ctf4/AND-1 protein hub, which links DNA replication, repair, and...
Ctf4 protein chemical biology chromosome stability protein-protein interactions stapled peptides Amino Acid Motifs Binding Sites Crystallography X-Ray DNA Polymerase I DNA-Binding Proteins Diazonium Compounds Fluorescence Polarization Genomic Instability Humans Molecular Dynamics Simulation Peptides Protein Interaction Domains and Motifs Protein Structure Tertiary Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins
Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions.
Sheikh Taslim Ali, Lin Wang, Eric HY Lau, Xiao-Ke Xu, Zhanwei Du, Ye Wu, Gabriel M Leung, Benjamin J Cowling
Oct 12, 2020
Studies of novel coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have reported varying estimates of epidemiological parameters, including serial interval...
Exploring the role of normative, financial and environmental information in promoting uptake of energy efficient technologies
The potential of normative and feedback (financial vs. environmental) information in guiding pro-environmental decision-making behaviour was explored in a 2 × 2 (plus control) choice experiment. Using the context of home...
behaviour change decision-making Energy efficient technologies Environmental behaviour Feedback frames Social Norms /dk/atira/pure/subjectarea/asjc/3200/3207 name=Social Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Latent infection of myeloid progenitors by human cytomegalovirus protects cells from FAS-mediated apoptosis through the cellular IL-10/PEA-15 pathway.
Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation
Betty Lau, Karen Kerr, Quan Gu, Katie Nightingale, Robin Antrobus, Nicolás M. Suárez, Richard J. Stanton, Eddie C. Y. Wang, Michael P. Weekes, Andrew J. Davison
Aug 05, 2020
Long non-coding RNAs (lncRNAs) are transcripts of >200 nucleotides that are not translated into functional proteins. Cellular lncRNAs have been shown to act as regulators by interacting with target nucleic acids or proteins and...
Response to Ruby et al
Does disruption of prefrontal cortical activity using transcranial magnetic stimulation (TMS) impair visual metacognition? An initial study supporting this idea (Rounis, Maniscalco, Rothwell, Passingham, & Lau, 2010) motivated...
Variation in the practice of tracheal intubation in Europe after traumatic brain injury
BY Gravesteijn, CA Sewalt, A Ercole, F Lecky, D Menon, EW Steyerberg, AIR Maas, HF Lingsma, M Klimek, CENTER-TBI collaborators
Aug 20, 2019
Traumatic brain injury patients frequently undergo tracheal intubation. We aimed to assess current intubation practice in Europe and identify variation in practice. We analysed data from patients with traumatic brain injury...
Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation.
Betty Lau, Karen Kerr, Quan Gu, Katie Nightingale, Robin Antrobus, Nicolás M Suárez, Richard J Stanton, Eddie CY Wang, Michael P Weekes, Andrew J Davison
Sep 09, 2020
Long non-coding RNAs (lncRNAs) are transcripts of >200 nucleotides that are not translated into functional proteins. Cellular lncRNAs have been shown to act as regulators by interacting with target nucleic acids or proteins and...
Brief screening for maternal mental health in Vietnam
HP Do, PR Baker, TV Vo, BY Luong-Thanh, LH Nguyen, S Valdebenito, M Eisner, BX Tran, TD Hoang, MP Dunne
Jan 18, 2021
Background: In many countries, there is limited consideration of the psychological wellbeing of women during antenatal and postnatal care. Among a range of contributing factors, one practical reason is that brief, valid and...
Identification and quantification of protein S-nitrosation by nitrite in the mouse heart during ischemia.
Edward T Chouchani, Andrew M James, Carmen Methner, Victoria R Pell, Tracy A Prime, Brian K Erickson, Marleen Forkink, Gigi Y Lau, Thomas P Bright, Katja E Menger, Ian M Fearnley, Thomas Krieg, Michael P Murphy
Mar 29, 2018
Nitrate (NO3-) and nitrite (NO2-) are known to be cardioprotective and to alter energy metabolism in vivo NO3- action results from its conversion to NO2- by salivary bacteria, but the mechanism(s) by which NO2- affects...
OxICAT S-nitrosation Heart Ischemia Mitochondria Nitrite Proteomics Redox Redox Regulation Affinity Labels Animals Cardiotonic Agents Cell Membrane Permeability Cysteine Disease Models Animal Female Heart Mice Mice Inbred C57BL Mitochondria Heart Mitochondria Liver Mitochondrial Swelling Myocardial Ischemia Myocardium Nitrates Nitrites Nitrosation Potassium Compounds Protein Processing Post-Translational Proteomics Rats Wistar Up-Regulation
CD154 Induces Interleukin-6 Secretion by Kidney Tubular Epithelial Cells under Hypoxic Conditions
Antoine Dewitte, Julien Villeneuve, Sébastien Lepreux, Marion Bouchecareilh, Xavier Gauthereau, Claire Rigothier, Christian Combe, Alexandre Ouattara, Jean Ripoche
Mar 26, 2020
Inflammation is a major contributor to tubular epithelium injury in kidney disorders, and the involvement of blood platelets in driving inflammation is increasingly stressed. CD154, the ligand of CD40, is one of the mediators...
Published by: Mediators of inflammation
Radiation-driven acceleration in the expanding WR140 dust shell.
The Wolf-Rayet (WR) binary system WR140 is a close (0.9-16.7 mas; ref. 1) binary star consisting of an O5 primary and WC7 companion2 and is known as the archetype of episodic dust-producing WRs. Dust in WR binaries is known to...
Selectively Interfering With Intrusive but Not Voluntary Memories of a Trauma Film
Intrusive memories of a traumatic event can be reduced by a subsequent interference procedure, seemingly sparing voluntary memory for that event. This selective-interference effect has potential therapeutic benefits (e.g., for...
How to produce a systematic review
When looking for an answer to a question, in most cases, hundreds, if not thousands of research papers have been published in that area. A systematic review attempts ‘to collate all empirical evidence that fits pre-specified...
Inferring time-varying generation time, serial interval, and incubation period distributions for COVID-19.
Dongxuan Chen, Yiu-Chung Lau, Xiao-Ke Xu, Lin Wang, Zhanwei Du, Tim K Tsang, Peng Wu, Eric HY Lau, Jacco Wallinga, Benjamin J Cowling, Sheikh Taslim Ali
Dec 14, 2022
The generation time distribution, reflecting the time between successive infections in transmission chains, is a key epidemiological parameter for describing COVID-19 transmission dynamics. However, because exact infection times...
A Bamboo-inspired Exoskeleton (BiEXO) Based on Carbon Fiber for Shoulder and Elbow Joints
This paper presents a novel cable-driven exoskeleton (BiEXO) for the upper limb including shoulder and elbow joints. BiEXO is made of carbon fiber that is inspired by the Bamboo structure. The key components of BiEXO are...
Bamboo cable-driven mechanism Carbon Carbon Fiber Elbow Electron tubes exoskeleton Exoskeletons Optical fiber cables Optical fiber sensors rehabilitation robots Shoulder upper limb /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/1700/1709 name=Human-Computer Interaction /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/subjectarea/asjc/2600/2606 name=Control and Optimization /dk/atira/pure/subjectarea/asjc/1700/1702 name=Artificial Intelligence
Selectively Interfering With Intrusive but Not Voluntary Memories of a Trauma Film
Intrusive memories of a traumatic event can be reduced by a subsequent interference procedure, seemingly sparing voluntary memory for that event. This selective-interference effect has potential therapeutic benefits (e.g., for...
Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes
We have studied the control and significance of IL-1 production in human leukocyte cultures during accessory cell-dependent, T lymphocyte mitogenesis using sensitive bioassays and immunolabeling techniques. In primary...
Published by: Rockefeller University
A Bamboo-inspired Exoskeleton (BiEXO) Based on Carbon Fiber for Shoulder and Elbow Joints
This paper presents a novel cable-driven exoskeleton (BiEXO) for the upper limb including shoulder and elbow joints. BiEXO is made of carbon fiber that is inspired by the Bamboo structure. The key components of BiEXO are...
Bamboo cable-driven mechanism Carbon Carbon Fiber Elbow Electron tubes exoskeleton Exoskeletons Optical fiber cables Optical fiber sensors rehabilitation robots Shoulder upper limb /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/1700/1709 name=Human-Computer Interaction /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/subjectarea/asjc/2600/2606 name=Control and Optimization /dk/atira/pure/subjectarea/asjc/1700/1702 name=Artificial Intelligence
Inferring time-varying generation time, serial interval, and incubation period distributions for COVID-19.
Dongxuan Chen, Yiu-Chung Lau, Xiao-Ke Xu, Lin Wang, Zhanwei Du, Tim K Tsang, Peng Wu, Eric HY Lau, Jacco Wallinga, Benjamin J Cowling, Sheikh Taslim Ali
Jan 11, 2023
The generation time distribution, reflecting the time between successive infections in transmission chains, is a key epidemiological parameter for describing COVID-19 transmission dynamics. However, because exact infection times...
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine B. Cadogan, Alan Lau, Frances M. Richards, Duncan I. Jodrell
Oct 27, 2020
Abstract: Background: Personalised medicine strategies may improve outcomes in pancreatic ductal adenocarcinoma (PDAC), but validation of predictive biomarkers is required. Having developed a clinical trial to assess the ATR...
Enhanced detection of early hepatocellular carcinoma by serum SELDI-TOF proteomic signature combined with alpha-fetoprotein marker.
Lei Chen, David WY Ho, Nikki PY Lee, Stella Sun, Brian Lam, Kwong-Fai Wong, Xin Yi, George K Lau, Eddy WY Ng, Terence CW Poon, Paul BS Lai, Zongwei Cai, Jirun Peng, Xisheng Leng, Ronnie TP Poon, John M Luk
Mar 08, 2021
BACKGROUND: Biomarkers for accurate diagnosis of early hepatocellular carcinoma (HCC) are limited in number and clinical validation. We applied SELDI-TOF-MS ProteinChip technology to identify serum profile for distinguishing HCC...
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