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Delving Into the IT Governance-Management Communication Interface
This work is devoted to addressing the IT governance - management communication aspects, considering that their responsibilities are different, but complementary, in developing an IT governance framework. Our research question...
Published by: IGI Global Scientific Publishing
Efficiency and accuracy of visual search develop at different rates from early childhood through early adulthood
Abstract: Most studies of visual search across the life span have focused on classic feature and conjunction searches in which observers search for a fixed, simple shape target among relatively homogeneous distractors over a...
Population biology and phenology of the colour polymorphic damselfly
<i>Ischnura elegans</i>
at its southern range limit in Cyprus
1. Geographically widespread species provide excellent opportunities to investigate how phenotypes change across large‐scale environmental gradients. Temperature is a fundamental environmental variable and an important...
Mending the Divide
Beatriz Santos Barreto
Apr 13, 2023
Latin American has made remarkable progress in the last twenty years regarding LGBTQ+ rights. More recently, LGBTQ‐related issues have had major impacts on national and regional politics. However, most of the literature about...
Variation in Surface Ionization Potentials of Pristine and Hydrated BiVO4
Bismuth vanadate (BiVO4) is a promising material for photoelectrochemical water splitting and photocatalytic degradation of organic moieties. We evaluate the ionization potentials of the (010) surface termination of BiVO4 using...
Propelling Children’s Empathy and Friendship
Schools play a crucial role in creating supportive and safe environments, and positive feelings are key in fostering such environments. Schools as Learning Communities, based on the dialogic participation of the whole...
Susana León-Jiménez, Beatriz Villarejo-Carballido, Garazi López de Aguileta, Lídia Puigvert
Sep 06, 2020
$\textit{Myriad's}$ impact on gene patents
Three years later, the landmark $\textit{Myriad}$ decision on gene patents has led to some striking and unforeseen implications.
Statistical critical reactive maintenance characterisation for digital twin implementation in universities
Purpose: Facilities management (FM) plays a key role in the performance of businesses to ensure the comfort of users and the sustainable use of natural resources over operation and maintenance. Nevertheless, reactive...
Impact of Interactive Learning Environments on Learning and Cognitive Development of Children With Special Educational Needs
Children with special educational needs (SEN) achieve lower educational levels than their peers without special needs, leading to a higher risk of social exclusion in the future. Inclusive education aims to promote learning and...
Efficiency and accuracy of visual search develop at different rates from early childhood through early adulthood.
L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.
Beatriz Castejón-Vega, Alejandro Rubio, Antonio J Pérez-Pulido, José L Quiles, Jon D Lane, Beatriz Fernández-Domínguez, María Begoña Cachón-González, Carmen Martín-Ruiz, Alberto Sanz, Timothy M Cox, Elísabet Alcocer-Gómez, Mario D Cordero
Jan 07, 2022
AIMS: Tay-Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by...
GM2 gangliosidosis L-arginine Autophagy mTOR Arginine Autophagosomes Autophagy Cathepsins FIBROBLASTS Gangliosidoses GM2 Hexosaminidase A Hexosaminidase B Humans Lysosomes Mutation Permeability Proto-Oncogene Proteins c-akt Sandhoff Disease Signal Transduction TOR Serine-Threonine Kinases Tay-Sachs Disease Transcriptome
Statistical critical reactive maintenance characterisation for digital twin implementation in universities
Purpose: Facilities management (FM) plays a key role in the performance of businesses to ensure the comfort of users and the sustainable use of natural resources over operation and maintenance. Nevertheless, reactive...
Efficiency and accuracy of visual search develop at different rates from early childhood through early adulthood
Abstract: Most studies of visual search across the life span have focused on classic feature and conjunction searches in which observers search for a fixed, simple shape target among relatively homogeneous distractors over a...
Variation in Surface Ionization Potentials of Pristine and Hydrated BiVO4
Bismuth vanadate (BiVO4) is a promising material for photoelectrochemical water splitting and photocatalytic degradation of organic moieties. We evaluate the ionization potentials of the (010) surface termination of BiVO4 using...
The effect of a change in co-payment on prescription drug demand in a National Health System
Cristina Hernández-Izquierdo, Beatriz González López-Valcárcel, Stephen Morris, Mariya Melnychuk, Ignacio Abásolo Alessón
Feb 24, 2020
OBJECTIVES: To test the heterogeneity of the effect of a change in pharmaceutical cost-sharing by therapeutic groups in a Spanish region. METHODS: Data: random sample (provided by the Canary Islands Health Service) of 40,471...
Modelling and Coordination of Building design
Marcio Presente de Souza, Beatriz Campos Fialho, Rita Cristina Ferreira, Marcio Minto Fabricio, Ricardo Codinhoto
Jan 31, 2023
The implementation of Building Information Modelling (BIM) in the Architecture, Engineering, Construction and Operations (AECO) industry requires multidisciplinary teams equipped with new technical and managerial skills....
Electronic excitations in molecular solids
Jonathan M. Skelton, E. Lora Da Silva, Rachel Crespo-Otero, Lauren E. Hatcher, Paul R. Raithby, Stephen C. Parker, Aron Walsh
Apr 01, 2015
As the spatial and temporal resolution accessible to experiment and theory converge, computational chemistry is an increasingly powerful tool for modelling and interpreting spectroscopic data. However, the study of molecular...
L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation
Beatriz Castejón-Vega, Alejandro Rubio, Antonio J. Pérez-Pulido, José L. Quiles, Jon D. Lane, Beatriz Fernández-Domínguez, María Begoña Cachón-González, Carmen Martín-Ruiz, Alberto Sanz, Timothy M. Cox, Elísabet Alcocer-Gómez, Mario D. Cordero
Nov 22, 2021
Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by...
Pharmaceutical Manufacturing and Health Information Technology
Pharmaceutical companies are seen as slow in adopting principles of operation excellence and advanced technologies. This article aims to explore the reasons why an industry, recognized as profitable and intensive in capital and...
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
Characterizing hippocampal dynamics with MEG
The hippocampus, a hub of activity for a variety of important cognitive processes, is a target of increasing interest for researchers and clinicians. Magnetoencephalography (MEG) is an attractive technique for imaging...
Resolving Recent Plant Radiations
Mario Fernández-Mazuecos, Greg Mellers, Beatriz Vigalondo, Llorenç Sáez, Pablo Vargas, Beverley J Glover
Mar 29, 2018
Disentangling species boundaries and phylogenetic relationships within recent evolutionary radiations is a challenge due to the poor morphological differentiation and low genetic divergence between species, frequently...
Amphioxus functional genomics and the origins of vertebrate gene regulation.
Ferdinand Marlétaz, Panos N Firbas, Ignacio Maeso, Juan J Tena, Ozren Bogdanovic, Malcolm Perry, Christopher DR Wyatt, Elisa de la Calle-Mustienes, Stephanie Bertrand, Demian Burguera, Rafael D Acemel, Simon J van Heeringen, Silvia Naranjo, Carlos Herrera-Ubeda, Ksenia Skvortsova, Sandra Jimenez-Gancedo, Daniel Aldea, Yamile Marquez, Lorena Buono, Iryna Kozmikova, Jon Permanyer, Alexandra Louis, Beatriz Albuixech-Crespo, Yann Le Petillon, Anthony Leon, Lucie Subirana, Piotr J Balwierz, Paul Edward Duckett, Ensieh Farahani, Jean-Marc Aury, Sophie Mangenot, Patrick Wincker, Ricard Albalat, Èlia Benito-Gutiérrez, Cristian Cañestro, Filipe Castro, Salvatore D'Aniello, David EK Ferrier, Shengfeng Huang, Vincent Laudet, Gabriel AB Marais, Pierre Pontarotti, Michael Schubert, Hervé Seitz, Ildiko Somorjai, Tokiharu Takahashi, Olivier Mirabeau, Anlong Xu, Jr-Kai Yu, Piero Carninci, Juan Ramon Martinez-Morales, Hugues Roest Crollius, Zbynek Kozmik, Matthew T Weirauch, Jordi Garcia-Fernàndez, Ryan Lister, Boris Lenhard, Peter WH Holland, Hector Escriva, Jose Luis Gómez-Skarmeta, Manuel Irimia
Feb 11, 2019
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications. Here we sequence the genome of the Mediterranean amphioxus...
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