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Lysosome positioning and mTOR activity in Lowe syndrome.
Lowe syndrome is a rare, developmental disorder caused by mutations in the phosphatase, OCRL. A study in this issue of EMBO Reports shows that OCRL is required for microtubule nucleation and that mutations in this protein lead...
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.
Maria Giovanna De Leo, Leopoldo Staiano, Mariella Vicinanza, Alessandro Luciani, Annamaria Carissimo, Margherita Mutarelli, Antonella Di Campli, Elena Polishchuk, Giuseppe Di Tullio, Valentina Morra, Elena Levtchenko, Francesca Oltrabella, Tobias Starborg, Michele Santoro, Diego di Bernardo, Olivier Devuyst, Martin Lowe, Diego L Medina, Andrea Ballabio, Maria Antonietta De Matteis
Sep 03, 2019
Phosphoinositides (PtdIns) control fundamental cell processes, and inherited defects of PtdIns kinases or phosphatases cause severe human diseases, including Lowe syndrome due to mutations in OCRL, which encodes a PtdIns(4,5)P2...
“He Was the One With the Gun!” Associative Memory for White and Black Faces Seen With Weapons
Much research has found that implicit associations between Black male faces and aggression afect dispositional judgments and decision-making, but there have been few investigations into downstream efects on explicit episodic...
Published by: Digital Commons @ Texas A&M University-San Antonio
Professor and Columbia Judge-Alumna Selected as Liberty Fellows
Winthrop University
Jan 01, 0001
The 23 Liberty Fellows are described as action-oriented leaders with ambitious goals for a stronger South Carolina and were selected from more than 400 nominations from across the state. Chosen as Winthrop Fellows are: DeAndrea...
Published by: Winthrop University
Assessing general cognitive and adaptive abilities in adults with Down syndrome
Sarah Hamburg, Bryony Lowe, Carla Marie Startin, Concepcion Padilla, Antonia Coppus, Wayne Silverman, Juan Fortea, Shahid Zaman, Elizabeth Head, Benjamin L Handen, Ira Lott, Weihong Song, André Strydom
Aug 29, 2020
BACKGROUND: Measures of general cognitive and adaptive ability in adults with Down syndrome (DS) used by previous studies vary substantially. This review summarises the different ability measures used previously, focusing on...
Dance Major from Lugoff, S.C., Earned Tillman Award
Winthrop University
Jan 01, 0001
Amanda Floyd earned a Bachelor of Arts degree in dance and wants to teach dance with the ultimate goal of working in choreography. The Tillman Award is the university's highest academic honor. Established in 1940 to honor former...
Published by: Winthrop University
Reparations for Racism: Why the Persistence of Institutional Racism in America Demands More Than Equal Opportunity for Black Citizens
Alexander Lowe
Jan 01, 0001
Black Americans African Americans Distributive justice reparations John Rawls justice as fairness institutional racism reflective equilibrium difference principle equality of opportunity African American Studies Civil Rights and Discrimination Ethics and Political Philosophy Inequality and Stratification Race, Ethnicity and Post-Colonial Studies United States History
Published by: Ursinus College
Killing Kindly: Applying Jens Timmermann's Kantian Ethics of Animal Welfare to the Modern System of Livestock Farming
Alexander Lowe
Jan 01, 0001
This essay seeks to contribute to this conversation in an ethically applicable way, addressing specifically the Kantian vein of animal welfare discussed by Dr. Jens Timmermann in his essay When the Tail Wags the Dog: Animal...
Kantian ethics animal welfare Jens Timmermann Pain sentient animals food living conditions Diet slaughter Animal Husbandry animal rights Animal Studies Ethics and Political Philosophy
Published by: Ursinus College
Interview with Julia Mobley Irwin
Julia Mobley Irwin
Jan 01, 0001
In her November 9, 1976 interview with Sally Tyler, Julia Mobley Irwin details her life as a day student in the early 1900s. Irwin recalls her favorite classes, describes uniforms, insists that there was never a swimming pool at...
Day Student uniforms Latin Class Winthrop Training School Graduation Swimming Pool Benjamin Tillman Class of 1904 Oral History
Published by: Winthrop University
Business Major Tapped as Tillman Award Recipient
Winthrop University
Jan 01, 0001
The Tillman Award is the university's highest academic honor. Established in 1940 to honor former S.C. Governor Benjamin Ryan Tillman, the award recognizes the graduate who has most consistently met the demands of academic...
Published by: Winthrop University
Reparations for Racism: Why the Persistence of Institutional Racism in America Demands More Than Equal Opportunity for Black Citizens
Alexander Lowe
Jan 01, 0001
This essay seeks to expose the causational effects of various forms of distributive justice on wealth inequality within the United States of America. Herein, several frameworks of distributive justice are assessed through John...
Racism Distributive justice reflective equilibrium reparations Rawls slavery egalitarianism desert-based Black Americans wealth inequality African American Studies Arts and Humanities Inequality and Stratification Philosophy race and ethnicity
Published by: Ursinus College
GHG assessment of Bore Hill Farm Biodigester
This study takes the Bore Hill Farm Biodigester (BHFB) facility as a case study to explore the sources of Greenhouse Gas (GHG) emissions associated with commercial Anaerobic Digestion (AD), and some of the factors affecting...
Does Exposure to Noise During Military Service Affect the Progression of Hearing Loss with Increasing Age?
It is traditionally believed that the effects of exposure to noise cease once the exposure itself has ceased. If this is the case, exposure to noise relatively early in life, for example during military service, should...
Ben Hammond Featured at Artists Programs
Winthrop News Service
Jan 01, 0001
Benjamin Franklin Hammond [1883-1970] worked as a cartoonist for the Wichita Eagle from 1912 to 1965. In addition to editorial and historical drawings, he is best-known for his cartoon characters, "Hoots" and "Quacks" which...
Newspaper Cartoonist Winthrop Training School "Hoots and Quacks" B. F. Hammond illustration Journalism Studies
Published by: Winthrop University
Guidelines for Diagnosing and Quantifying Noise-Induced Hearing Loss
This paper makes recommendations for the diagnosis and quantification of noise-induced hearing loss (NIHL) in a medico-legal context. A distinction is made between NIHL produced by: steady broadband noise, as occurs in some...
Guidelines for Diagnosing and Quantifying Noise-Induced Hearing Loss.
This paper makes recommendations for the diagnosis and quantification of noise-induced hearing loss (NIHL) in a medico-legal context. A distinction is made between NIHL produced by: steady broadband noise, as occurs in some...
Advancing tephrochronology as a global dating tool
Layers of far-travelled volcanic ash (tephra) from explosive volcanic eruptions provide stratigraphic and numerical dating horizons in sedimentary and volcanic sequences. Such tephra layers may be dispersed over tens to...
Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins.
Consensus-designed tetratricopeptide repeat proteins are highly stable, modular proteins that are strikingly amenable to rational engineering. They therefore have tremendous potential as building blocks for biomaterials and...
A comparison of analytical techniques and the products formed during the decomposition of biodiesel under accelerated conditions
Christopher J Chuck, Christopher D Bannister, Rhodri W Jenkins, John P Lowe, Matthew G Davidson
Jun 01, 2012
Biodiesel is a renewable fuel synthesised from plant, waste or algal oils. Though biodiesel can be used as a replacement for diesel fuel, a number of technical issues, including the reduced oxidative stability, limit the...
Practical aspects of real-time reaction monitoring using multi-nuclear high resolution FlowNMR spectroscopy
Andrew M. R. Hall, Jonathan C. Chouler, Anna Codina, Peter T. Gierth, John P. Lowe, Ulrich Hintermair
Dec 21, 2016
FlowNMR spectroscopy is an excellent technique for non-invasive real-time reaction monitoring under relevant conditions that avoids many of the limitations that bedevil other reaction monitoring techniques. With the recent...
Student-Athlete and Biology Major Hannah Hadaway Receives Tillman Award
Winthrop University
Jan 01, 0001
The Rural Retreat, Va., resident was among more than 600 students who received degrees including 38 student-athletes at the ceremony at the Winthrop Coliseum. The Tillman Award, established in 1940 to honor former S.C. Governor...
Published by: Winthrop University
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