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Interview with Ethel Hughes Muhvich
Ethel Hughes Muhvich
Jan 01, 0001
In her November 11, 2004 interview with Lauren Weldishofer, Ethel Hughes Muhvich recalls her time in service during WWII. Muhvich describes why she enlisted, what her assignment was, and why her generation was the greatest. This...
Published by: Winthrop University
On the Hughes' model for pedestrian flow
In this paper we investigate the mathematical theory of Hughes' model for the flow of pedestrians (cf. Hughes (2002) [17]), consisting of a non-linear conservation law for the density of pedestrians coupled with an eikonal...
Wind Orchestra Records CD at Annual Convention
Winthrop University
Jan 01, 0001
The Winthrop/Carolinas Wind Orchestra completed a CD recording during the American Bandmasters Association's 76th Annual Convention. To purchase the CD, call the Department of Music at 803/323-2255.
Published by: Winthrop University
On the Hughes' model for pedestrian flow
In this paper we investigate the mathematical theory of Hughes' model for the flow of pedestrians (cf. Hughes (2002) [17]), consisting of a non-linear conservation law for the density of pedestrians coupled with an eikonal...
Unexpected Migratory Insertion Reactions of M(alkyl)<sub>2</sub> (M = Zn, Cd) and Diamidocarbenes
The electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit...
Unexpected Migratory Insertion Reactions of M(alkyl)<sub>2</sub> (M = Zn, Cd) and Diamidocarbenes
The electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit...
The one-dimensional Hughes model for pedestrian flow
This paper deals with a coupled system consisting of a scalar conservation law and an eikonal equation, called the Hughes model. Introduced in [24], this model attempts to describe the motion of pedestrians in a densely crowded...
Simple pyrazoline and pyrazole “turn on” fluorescent sensors selective for Cd<sup>2+</sup> and Zn<sup>2+</sup> in MeCN
An efficient two-step synthesis of pyrazoline ligand 1 is described which is an effective “turn on” fluorescent sensor for Cd2+ in MeCN. Oxidation to the corresponding pyrazole ligand 2 creates a “turn on”...
The one-dimensional Hughes model for pedestrian flow
This paper deals with a coupled system consisting of a scalar conservation law and an eikonal equation, called the Hughes model. Introduced in [24], this model attempts to describe the motion of pedestrians in a densely crowded...
Simple pyrazoline and pyrazole “turn on” fluorescent sensors selective for Cd<sup>2+</sup> and Zn<sup>2+</sup> in MeCN
An efficient two-step synthesis of pyrazoline ligand 1 is described which is an effective “turn on” fluorescent sensor for Cd2+ in MeCN. Oxidation to the corresponding pyrazole ligand 2 creates a “turn on”...
Perseveration and choice in Parkinson's disease
We have previously shown that patients with Parkinson's disease (PD) perseverate in their choice of action relative to healthy controls, and that this is affected by dopaminergic medication (Hughes LE, Barker RA, Owen AM, Rowe...
DSU Welcomes New Leadership to Board
Winthrop University
Jan 01, 0001
Senior Brandy Hughes (Branchville, S.C.) is the new Dinkins Student Union Board president. Hughes is a sociology/political science major.
Published by: Winthrop University
Ann Hughes. Gangraena and the Struggle for the English Revolution. Oxford
David L Smith
May 08, 2019
This is a big book about an even bigger book. Thomas Edwards’s Gangraena has featured in many works on the English Revolution, but this is the first full-length study devoted to the book in all its facets. As such it is very...
Winthrop Student Killed in Weekend Car Accident
Winthrop University
Jan 01, 0001
Hughes, 21, of Conway, S.C., was a senior majoring in special education at Winthrop. Hughes was an active member of the Winthrop Quidditch Team. Students Christian McBee and Caitlin Livingston were also injured in the accident.
Published by: Winthrop University
Mycolic Acids of Mycobacterium tuberculosis: An Achilles Heel or a Neutralizing Weapon
The Rockefeller University
Jan 01, 0001
On January 19, 2001, The Rockefeller University presented Infectious Disease Centennial Lecture by William Jacobs Jr., Ph.D. (Howard Hughes Medical Institute).
Published by: The Rockefeller University
Testing the Ecophenotype Model
Marlene Staginnus, Harriet Cornwell, Nicola Toschi, Maaike Oosterling, Michal Paradysz, Areti Smaragdi, Karen González-Madruga, Ruth Pauli, Jack C. Rogers, Anka Bernhard, Anne Martinelli, Gregor Kohls, Nora Maria Raschle, Kerstin Konrad, Christina Stadler, Christine M. Freitag, Stephane A. De Brito, Graeme Fairchild
Jun 05, 2023
Background:
Childhood maltreatment is common in youths with conduct disorder (CD), and both CD and maltreatment have been linked to neuroanatomical alterations. Nonetheless, our understanding of the contribution of...
Childhood maltreatment is common in youths with conduct disorder (CD), and both CD and maltreatment have been linked to neuroanatomical alterations. Nonetheless, our understanding of the contribution of...
antisocial behavior Brain structure Childhood maltreatment Conduct Disorder Cortical thickness surface-based morphometry /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging
Testing the Ecophenotype Model
Marlene Staginnus, Harriet Cornwell, Nicola Toschi, Maaike Oosterling, Michal Paradysz, Areti Smaragdi, Karen González-Madruga, Ruth Pauli, Jack C. Rogers, Anka Bernhard, Anne Martinelli, Gregor Kohls, Nora Maria Raschle, Kerstin Konrad, Christina Stadler, Christine M. Freitag, Stephane A. De Brito, Graeme Fairchild
Jun 05, 2023
Background:
Childhood maltreatment is common in youths with conduct disorder (CD), and both CD and maltreatment have been linked to neuroanatomical alterations. Nonetheless, our understanding of the contribution of...
Childhood maltreatment is common in youths with conduct disorder (CD), and both CD and maltreatment have been linked to neuroanatomical alterations. Nonetheless, our understanding of the contribution of...
antisocial behavior Brain structure Childhood maltreatment Conduct Disorder Cortical thickness surface-based morphometry /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/2700/2741 name=Radiology Nuclear Medicine and imaging
Positive and Negative Parenting in Conduct Disorder with High versus Low Levels of Callous-Unemotional Traits
Ruth Pauli, Peter Tino, Jack C. Rogers, Rosalind Baker, Roberta Clanton, Philippa Birch, Abigail Brown, Gemma Daniel, Lisandra Ferreira, Liam Grisley, Gregor Kohls, Christina Stadler, Aranzazu Fernandez-Rivas, Graeme Fairchild, Arne Popma, Dimitris Dikeos, Beate Herpertz-Dahlmann, Kerstin Konrad, Christine M. Freitag, Pia Rotshtein, Stephane A. De Brito
Aug 31, 2021
Less is known about the relationship between conduct disorder (CD), callous-unemotional (CU) traits and positive and negative parenting in adolescence compared to early childhood. We combined traditional univariate analyses with...
Mapping the structural organization of the brain in conduct disorder
Graeme Fairchild, Nicola Toschi, Kate Sully, Edmund Sonuga-Barke, Cindy Hagan, Stefano Diciotti, Ian Goodyer, Andrew Calder, Luca Passamonti
Aug 18, 2016
BACKGROUND: Neuroimaging methods that allow researchers to investigate structural covariance between brain regions are increasingly being used to study psychiatric disorders. Structural covariance analyses are particularly well...
Cortical thickness, surface area, and folding alterations in male youths with conduct disorder and varying levels of callous-unemotional traits
Graeme Fairchild, Nicola Toschi, Cindy Hagan, Ian Goodyer, Andrew Calder, Luca Passamonti
Apr 30, 2015
PURPOSE: Previous studies have reported changes in gray matter volume in youths with conduct disorder (CD), although these differences are difficult to interpret as they may have been driven by alterations in cortical thickness...
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
D Klenerman, M Iljina, L Hong, MH Horrocks, MH Ludtmann, ML Choi, CD Hughes, FS Ruggeri, T Guilliams, AK Buell, J-E Lee, S Gandhi, SF Lee, CE Bryant, M Vendruscolo, TPJ Knowles, CM Dobson, E De Genst, D Klenerman
Jul 04, 2017
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk
Anka Bernhard, Marietta Kirchner, Anne Martinelli, Katharina Ackermann, Gregor Kohls, Karen Gonzalez-Madruga, Amy Wells, Aranzazu Fernández-Rivas, Maider Gonzalez De Artaza-Lavesa, Nora Maria Raschle, Angeliki Konsta, Réka Siklósi, Amaia Hervás, Beate Herpertz-Dahlmann, Stephane A. De Brito, Arne Popma, Christina Stadler, Kerstin Konrad, Graeme Fairchild, Christine M. Freitag
Aug 31, 2021
Conduct Disorder (CD) is characterized by severe aggressive and antisocial behavior. The stress hormone system has frequently been investigated as a neurobiological correlate of CD, while other interacting neuroendocrine...
Conduct Disorder Environmental risk factors FEMNAT-CD Neuropeptides Sex differences Steroid hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2800/2808 name=Neurology /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Predicting budesonide performance in healthy subjects and patients with Crohn's disease using biorelevant in vitro dissolution testing and PBPK modeling
Objectives: Drug product performance might be affected in Crohn's disease (CD) patients compared to healthy subjects due to pathophysiological changes. Since a low number of clinical studies is performed in this patient...
Investigating Sex Differences in Emotion Recognition, Learning, and Regulation among Youths with Conduct Disorder
Gregor Kohls, Sarah Baumann, Malou Gundlach, Wolfgang Scharke, Anka Bernhard, Anne Martinelli, Katharina Ackermann, Linda Kersten, Martin Prätzlich, Helena Oldenhof, Lucres Jansen, Lisette van den Boogaard, Areti Smaragdi, Karen Gonzalez-Madruga, Harriet Cornwell, Jack Rogers, Ruth Pauli, Roberta Clanton, Rosalind Baker, Aitana Bigorra Gualba, Beate Herpertz-Dahlmann, Aranzazu Fernández-Rivas, Arne Popma, Christina Stadler, Stephane De Brito, James Blair, Christine M. Freitag, Graeme Fairchild, Kerstin Konrad
Feb 01, 2020
Objective: Conduct disorder (CD) is a serious neurodevelopmental disorder marked by notably higher prevalence rates for boys than girls. Converging evidence suggests that CD is associated with impairments in emotion...
FEMNAT-CD Callous-unemotional traits Conduct Disorder emotion processing Sex differences /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Neuroendocrine Stress Response in Female and Male Youths With Conduct Disorder and Associations With Early Adversity
Anka Bernhard, Katharina Ackermann, Anne Martinelli, Andreas G. Chiocchetti, Leonora Vllasaliu, Karen González-Madruga, Molly Batchelor, Nora M. Raschle, Helena Oldenhof, Lucres M.C. Jansen, Gregor Kohls, Kerstin Konrad, Arne Popma, Christina Stadler, Graeme Fairchild, Christine M. Freitag
May 31, 2022
Objective: Conduct disorder (CD) involves aggressive and antisocial behavior and is associated with blunted cortisol stress response in male youths. Far less is known about cortisol stress responsivity in female youths with...
Conduct Disorder Cortisol Oxytocin Stress response Testosterone /dk/atira/pure/subjectarea/asjc/3200/3204 name=Developmental and Educational Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
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